(Q35057345)

6 August 2017

1 reference

title

Agonist induction and conformational selection during activation of a G-protein-coupled receptor (English)

1 reference

G protein-coupled receptor

6 August 2017

0 references

author name string

László Hunyady

series ordinal

1

1 reference

PubMed ID

12559772

6 August 2017

Georges Vauquelin

series ordinal

2

1 reference

PubMed ID

12559772

6 August 2017

Patrick Vanderheyden

series ordinal

3

1 reference

6 August 2017

1 February 2003

1 reference

Trends in Pharmacological Sciences

6 August 2017

1 reference

6 August 2017

24

1 reference

6 August 2017

2

1 reference

6 August 2017

81-86

1 reference

Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Activation of the alpha1b-adrenergic receptor is initiated by disruption of an interhelical salt bridge constraint

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Mutagenesis and modelling of the alpha(1b)-adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Rhodopsin: insights from recent structural studies.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Lessons from constitutively active mutants of G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

The active state of the AT1 angiotensin receptor is generated by angiotensin II induction

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Mutation of Asn111 in the third transmembrane domain of the AT1A angiotensin II receptor induces its constitutive activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

The conformational change responsible for AT1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Identification of a conserved switch residue responsible for selective constitutive activation of the beta2-adrenergic receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Alanine exchanges of polar amino acids in the transmembrane domains of a platelet-activating factor receptor generate both constitutively active and inactive mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Constitutive activation of the human bradykinin B2 receptor induced by mutations in transmembrane helices III and VI.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Constitutively active mutants of rhodopsin

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Interaction of biphenylimidazole and imidazoleacrylic acid nonpeptide antagonists with valine 108 in TM III of the AT1 angiotensin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Mechanism of constitutive activation of the AT1 receptor: influence of the size of the agonist switch binding residue Asn(111).

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Angiotensin IV is a potent agonist for constitutive active human AT1 receptors. Distinct roles of the N-and C-terminal residues of angiotensin II during AT1 receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

The docking of Arg2 of angiotensin II with Asp281 of AT1 receptor is essential for full agonism

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

G protein-coupled receptors. II. Mechanism of agonist activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

The ligand paradox between affinity and efficacy: can you be there and not make a difference?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Agonist-induced phosphorylation of the angiotensin II (AT(1A)) receptor requires generation of a conformation that is distinct from the inositol phosphate-signaling state

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Rhodopsin: structural basis of molecular physiology

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Mutational analysis of the interaction of the N- and C-terminal ends of angiotensin II with the rat AT(1A) receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Interaction of Phe8 of angiotensin II with Lys199 and His256 of AT1 receptor in agonist activation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

The ligand binding site of the angiotensin AT1 receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

Amino acids of the third transmembrane domain of the AT1A angiotensin II receptor are involved in the differential recognition of peptide and nonpeptide ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900050-0

7 January 2021

10.1016/S0165-6147(02)00050-0

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12559772