(Q35066769)

6 August 2017

title

Synergistic induction of apoptosis in A549 cells by dihydroartemisinin and gemcitabine (English)

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6 August 2017

Chubiao Zhao

1

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6 August 2017

Weijie Gao

series ordinal

2

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6 August 2017

Tongsheng Chen

series ordinal

3

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6 August 2017

publication date

1 April 2014

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6 August 2017

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6 August 2017

volume

19

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6 August 2017

issue

4

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6 August 2017

page(s)

668-681

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Dihydroartemisinin inactivates NF-kappaB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo.

6 August 2017

cites work

1 reference

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Proteasome inhibition sensitizes non-small-cell lung cancer to gemcitabine-induced apoptosis

21 January 2018

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Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death

21 January 2018

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A kinome screen identifies checkpoint kinase 1 (CHK1) as a sensitizer for RRM1-dependent gemcitabine efficacy

21 January 2018

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Role of mitochondrial uncoupling protein 2 in cancer cell resistance to gemcitabine

21 January 2018

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Experimental Therapy of Hepatoma with Artemisinin and Its Derivatives: In vitro and In vivo Activity, Chemosensitization, and Mechanisms of Action

21 January 2018

1 reference

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Ionizing radiation potentiates dihydroartemisinin-induced apoptosis of A549 cells via a caspase-8-dependent pathway

21 January 2018

1 reference

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First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases

21 January 2018

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Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy

21 January 2018

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Histone deacetylase inhibitors facilitate dihydroartemisinin-induced apoptosis in liver cancer in vitro and in vivo

21 January 2018

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In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents

21 January 2018

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The antimalarial agent artesunate possesses anticancer properties that can be enhanced by combination strategies.

21 January 2018

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Artesunate induces oxidative DNA damage, sustained DNA double-strand breaks, and the ATM/ATR damage response in cancer cells

21 January 2018

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Amplification activation loop between caspase-8 and -9 dominates artemisinin-induced apoptosis of ASTC-a-1 cells

21 January 2018

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Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

21 January 2018

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Artesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells

21 January 2018

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Death receptors: signaling and modulation

21 January 2018

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Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.

21 January 2018

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Molecular biology of Bax and Bak activation and action

21 January 2018

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ROS stress in cancer cells and therapeutic implications

21 January 2018

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Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine.

21 January 2018

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Single-cell analysis of dihydroartemisinin–induced apoptosis through reactive oxygen species–mediated caspase-8 activation and mitochondrial pathway in ASTC-a-1 cells using fluorescence imaging techniques

21 January 2018

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The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells.

21 January 2018

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Dihydroartemisinin inhibits growth of pancreatic cancer cells in vitro and in vivo

21 January 2018

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Dihydroartemisinin inhibits angiogenesis in pancreatic cancer by targeting the NF-κB pathway.

21 January 2018

1 reference

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Extracellular signal-regulated kinase activation and Bcl-2 downregulation mediate apoptosis after gemcitabine treatment partly via a p53-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0953-0

Phosphorylation status of heat shock protein 27 plays a key role in gemcitabine-induced apoptosis of pancreatic cancer cells

21 January 2018

1 reference

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Long circulation and cytotoxicity of PEGylated gemcitabine and its potential for the treatment of pancreatic cancer

21 January 2018

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Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells

21 January 2018

1 reference

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The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials

21 January 2018

1 reference

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Anticancer activities of artemisinin and its bioactive derivatives

21 January 2018

1 reference

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Cytochrome c release from mitochondria proceeds by a two-step process

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0953-0

The JNK inhibitor SP600125 enhances dihydroartemisinin-induced apoptosis by accelerating Bax translocation into mitochondria in human lung adenocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0953-0

Multistep and multitask Bax activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0953-0

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0953-0

Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0953-0

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0953-0

Dihydroartemisinin Induces Apoptosis by a Bak-Dependent Intrinsic Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0953-0

Life and death in peripheral T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0953-0

Evidence for the Involvement of Carbon-centered Radicals in the Induction of Apoptotic Cell Death by Artemisinin Compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-013-0953-0

10.1007/S10495-013-0953-0

21 January 2018

Identifiers

DOI

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6 August 2017

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