(Q35067810)

English

Nucleation capacity and presence of centrioles define a distinct category of centrosome abnormalities that induces multipolar mitoses in cancer cells

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

6 August 2017

Nucleation capacity and presence of centrioles define a distinct category of centrosome abnormalities that induces multipolar mitoses in cancer cells (English)

1 reference

Europe PubMed Central

6 August 2017

author name string

Michael J Difilippantonio

1

1 reference

Europe PubMed Central

6 August 2017

B Michael Ghadimi

2

1 reference

Europe PubMed Central

6 August 2017

Tamara Howard

3

1 reference

Europe PubMed Central

6 August 2017

Jordi Camps

4

1 reference

Europe PubMed Central

6 August 2017

Quang Tri Nguyen

5

1 reference

Europe PubMed Central

6 August 2017

Douglas K Ferris

6

1 reference

Europe PubMed Central

6 August 2017

Dan L Sackett

7

1 reference

Europe PubMed Central

6 August 2017

Thomas Ried

8

1 reference

Europe PubMed Central

6 August 2017

publication date

1 October 2009

1 reference

Europe PubMed Central

6 August 2017

Environmental and Molecular Mutagenesis

1 reference

Europe PubMed Central

6 August 2017

50

1 reference

Europe PubMed Central

6 August 2017

8

1 reference

Europe PubMed Central

6 August 2017

672-696

1 reference

Europe PubMed Central

6 August 2017

Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Introduction to microarray technology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Generations of sequencing technologies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

The centrosome is a polyfunctional multiprotein cell complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Chromosomal breakpoints in primary colon cancer cluster at sites of structural variants in the genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Centrin 2 localizes to the vertebrate nuclear pore and plays a role in mRNA and protein export

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Cooperation between mitotic kinesins controls the late stages of cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Cell division: timing the machine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Xeroderma pigmentosum group C protein possesses a high affinity binding site to human centrin 2 and calmodulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

GCP5 and GCP6: two new members of the human gamma-tubulin complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Centrosome duplication. a centriolar pas de deux

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Managing the centrosome numbers game: from chaos to stability in cancer cell division

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

The mitotic machinery as a source of genetic instability in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Genomic changes defining the genesis, progression, and malignancy potential in solid human tumors: a phenotype/genotype correlation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Association of polo-like kinase with alpha-, beta- and gamma-tubulins in a stable complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Genetic instabilities in human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Tubulin as a target for anticancer drugs: agents which interact with the mitotic spindle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Activated polo-like kinase Plx1 is required at multiple points during mitosis in Xenopus laevis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Multicolor Spectral Karyotyping of Human Chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Abnormal centrosome amplification in the absence of p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Microtubule nucleation by gamma-tubulin-containing rings in the centrosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Pericentrin, a highly conserved centrosome protein involved in microtubule organization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Centrin, centrosomes, and mitotic spindle poles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Centrosomal kinases, HsAIRK1 and HsAIRK3, are overexpressed in primary colorectal cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

8 July 2018

Ultrastructural Studies of Surface Features of Human Normal and Tumor Cells in Tissue Culture by Scanning and Transmission Electron Microscopy2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

28 July 2018

Polo-like Kinase 1 Triggers the Initiation of Cytokinesis in Human Cells by Promoting Recruitment of the RhoGEF Ect2 to the Central Spindle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

27 September 2018

A feedback loop in the polo-like kinase activation pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

27 September 2018

XMAP215 is required for the microtubule-nucleating activity of centrosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

27 September 2018

Purification and cloning of a protein kinase that phosphorylates and activates the polo-like kinase Plx1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

27 September 2018

Polar organization of gamma-tubulin in acentriolar mitotic spindles of Drosophila melanogaster cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322947

27 September 2018

Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/19768832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

1 reference

https://pubmed.ncbi.nlm.nih.gov/19768832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between centrosome abnormalities and chromosomal instability in human pancreatic cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19768832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polo-like kinase is a cell cycle-regulated kinase activated during mitosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19768832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Supernumerary centrosomes and cancer: Boveri's hypothesis resurrected

1 reference

https://pubmed.ncbi.nlm.nih.gov/19768832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Centrosome defects and genetic instability in malignant tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19768832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Centrosomal deployment of gamma-tubulin and pericentrin: evidence for a microtubule-nucleating domain and a minus-end docking domain in certain mouse epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19768832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

1 reference

https://api.crossref.org/works/10.1002%2FEM.20532

7 January 2021

based on heuristic

inferred from DOI database lookup

Planting the seeds of biotechnology

1 reference

https://api.crossref.org/works/10.1002%2FEM.20532

7 January 2021

based on heuristic

inferred from DOI database lookup

Homage to Theodor Boveri (1862-1915): Boveri's theory of cancer as a disease of the chromosomes, and the landscape of genomic imbalances in human carcinomas.

1 reference

https://api.crossref.org/works/10.1002%2FEM.20532

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/EM.20532

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q35067810&oldid=1448278525"