(Q35069689)

6 August 2017

Effects of direct Renin inhibition on myocardial fibrosis and cardiac fibroblast function (English)

1 reference

6 August 2017

2

Ivan Luptak

1 reference

6 August 2017

Hui Zhi

1

1 reference

6 August 2017

Gaurav Alreja

3

1 reference

6 August 2017

Jianru Shi

4

1 reference

6 August 2017

Jian Guan

5

1 reference

6 August 2017

Nicole Metes-Kosik

6

1 reference

6 August 2017

Jacob Joseph

7

1 reference

6 August 2017

language of work or name

English

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publication date

11 December 2013

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6 August 2017

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6 August 2017

8

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6 August 2017

12

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6 August 2017

e81612

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Creative Commons CC0 License

6 August 2017

start time

11 December 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

Homocysteine enhances MMP-9 production in murine macrophages via ERK and Akt signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859492

Homocysteine-induced macrophage inflammatory protein-2 production by glomerular mesangial cells is mediated by PI3 Kinase and p38 MAPK

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859492

Quo vadis: whither homocysteine research?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859492

Cross-sectional relations of multiple biomarkers representing distinct biological pathways to plasma markers of collagen metabolism in the community

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859492

Irbesartan in patients with heart failure and preserved ejection fraction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859492

Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859492

Trends in prevalence and outcome of heart failure with preserved ejection fraction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859492

Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859492

Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859492

Modulation of angiotensin II signaling for GATA4 activation by homocysteine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859492

Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859492

Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Renin inhibition improves cardiac function and remodeling after myocardial infarction independent of blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Effect of anti-oxidant treatment on hyperhomocysteinemia-induced myocardial fibrosis and diastolic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Hyperhomocysteinemia leads to adverse cardiac remodeling in hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Cardiovascular effects of hyperhomocysteinemia in conscious unrestrained rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Effect of long-term hyperhomocysteinemia on myocardial structure and function in hypertensive rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Reversal of endocardial endothelial dysfunction by folic acid in homocysteinemic hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Plasma homocysteine and risk for congestive heart failure in adults without prior myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Chronic methionine load-induced hyperhomocysteinemia enhances rat carotid responsiveness for angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Small artery mechanics in hyperhomocysteinemic mice: effects of angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Captopril Restores Endothelium-Dependent Relaxation of Rat Aortic Rings After Exposure to Homocysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

A reduction of endogenous asymmetric dimethylarginine contributes to the effect of captopril on endothelial dysfunction induced by homocysteine in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Dyrk1A, a serine/threonine kinase, is involved in ERK and Akt activation in the brain of hyperhomocysteinemic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Evidence that AKT and GSK-3β pathway are involved in acute hyperhomocysteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Homocysteine induces smooth muscle cell proliferation through differential regulation of cyclins A and D1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Homocysteine enhances cell proliferation in hepatic myofibroblastic stellate cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Role of NMDA receptor in homocysteine-induced activation of mitogen-activated protein kinase and phosphatidyl inositol 3-kinase pathways in cultured human vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Targeting TGF-β overexpression in renal disease: Maximizing the antifibrotic action of angiotensin II blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081612

Matrix metalloproteinases/tissue inhibitors of metalloproteinases: relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease

21 January 2018

1 reference

12 December 2020

Inhibition of renin/prorenin receptor attenuated mesangial cell proliferation and reduced associated fibrotic factor release

1 reference

12 December 2020

Double antibody radioimmunoassay of renin activity and angiotensin II in human peripheral plasma

1 reference

12 December 2020

The perindopril in elderly people with chronic heart failure (PEP-CHF) study

1 reference

12 December 2020

Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via epidermal growth factor receptor-mediated extracellular signal-regulated kinase and Akt activation pathway

1 reference

12 December 2020

Renal protective effects of aliskiren beyond its antihypertensive property in a mouse model of progressive fibrosis

1 reference

12 December 2020

A noninvasive computerized tail-cuff system for measuring blood pressure in mice

1 reference

12 December 2020

Impairment of cerebrovascular reactivity by methionine-induced hyperhomocysteinemia and amelioration by quinapril treatment

1 reference

12 December 2020

Aliskiren in combination with valsartan exerts synergistic protective effects against ventricular remodeling after myocardial infarction in mice

1 reference

12 December 2020

Renin is an angiotensin-independent profibrotic mediator: role in pulmonary fibrosis

1 reference

12 December 2020

Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0081612

Identifiers

DOI

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6 August 2017

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6 August 2017

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