(Q35070682)

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Autoreactive cytotoxic T lymphocytes acquire higher expression of cytotoxic effector markers in the islets of NOD mice after priming in pancreatic lymph nodes

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Europe PubMed Central

PubMed publication ID

6 August 2017

Autoreactive cytotoxic T lymphocytes acquire higher expression of cytotoxic effector markers in the islets of NOD mice after priming in pancreatic lymph nodes (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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author name string

Kate L Graham

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Balasubramanian Krishnamurthy

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Stacey Fynch

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Zia U Mollah

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Robyn Slattery

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Pere Santamaria

6

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Thomas W Kay

7

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Helen E Thomas

8

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Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

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publication date

1 June 2011

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Europe PubMed Central

PubMed publication ID

6 August 2017

The American Journal of Pathology

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Europe PubMed Central

PubMed publication ID

6 August 2017

178

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Europe PubMed Central

PubMed publication ID

6 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

2716-2725

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

In situ recognition of autoantigen as an essential gatekeeper in autoimmune CD8+ T cell inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Prevention of diabetes by FTY720-mediated stabilization of peri-islet tertiary lymphoid organs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Finding a way out: lymphocyte egress from lymphoid organs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

IL-2 regulates perforin and granzyme gene expression in CD8+ T cells independently of its effects on survival and proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Effector CD8+ T cells recovered from an influenza pneumonia differentiate to a state of focused gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Activation, differentiation, and migration of naive virus-specific CD8+ T cells during pulmonary influenza virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Beta cell MHC class I is a late requirement for diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Single-cell perforin and granzyme expression reveals the anatomical localization of effector CD8+ T cells in influenza virus-infected mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Unlocking the secrets of cytotoxic granule proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Herpes simplex virus type 1-specific cytotoxic T-lymphocyte arming occurs within lymph nodes draining the site of cutaneous infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

IFN-gamma action on pancreatic beta cells causes class I MHC upregulation but not diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

8 July 2018

Evolution of ectopic lymphoid neogenesis and in situ autoantibody production in autoimmune nonobese diabetic mice: cellular and molecular characterization of tertiary lymphoid structures in pancreatic islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

27 September 2018

CD8(+) T cells specific for beta cells encounter their cognate antigens in the islets of NOD mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

27 September 2018

Cutting edge: local recall responses by memory T cells newly recruited to peripheral nonlymphoid tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

27 September 2018

Cell cycle-related acquisition of cytotoxic mediators defines the progressive differentiation to effector status for virus-specific CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

27 September 2018

Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

27 September 2018

B-cells promote intra-islet CD8+ cytotoxic T-cell survival to enhance type 1 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

27 September 2018

Increased NF-kappa B activity in B cells and bone marrow-derived dendritic cells from NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

27 September 2018

Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

27 September 2018

Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

27 September 2018

NF-kappa B hyperactivation has differential effects on the APC function of nonobese diabetic mouse macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

27 September 2018

Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

27 September 2018

Elevated NF-kappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

27 September 2018

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

27 September 2018

Dendritic Cell-Induced Memory T Cell Activation in Nonlymphoid Tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

16 November 2018

Cytotoxic T-Cells From T-Cell Receptor Transgenic NOD8.3 Mice Destroy β-Cells via the Perforin and Fas Pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124028

16 November 2018

Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21641394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-21 promotes differentiation of naive CD8 T cells to a unique effector phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/21641394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic cells from nonobese diabetic mice exhibit a defect in NF-kappa B regulation due to a hyperactive I kappa B kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21641394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21641394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoreactive alpha-interferon in insulin-secreting beta cells in type 1 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21641394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21641394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21641394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21641394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant

1 reference

https://pubmed.ncbi.nlm.nih.gov/21641394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of insulitis and diabetes in beta 2-microglobulin-deficient non-obese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21641394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon expression in the pancreases of patients with type I diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21641394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new method for isolation of murine islets with markedly improved yields

1 reference

https://pubmed.ncbi.nlm.nih.gov/21641394

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.AJPATH.2011.02.015

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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