(Q35072867)

6 August 2017

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title

Human class IV alcohol dehydrogenase: kinetic mechanism, functional roles and medical relevance (English)

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6 August 2017

Shih-Jiun Yin

1

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6 August 2017

Chu-Fang Chou

2

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6 August 2017

Ching-Long Lai

3

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6 August 2017

Shou-Lun Lee

4

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6 August 2017

Chih-Li Han

5

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6 August 2017

publication date

1 February 2003

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Chemico-biological Interactions

6 August 2017

published in

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6 August 2017

volume

143-144

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6 August 2017

page(s)

219-227

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Pharmacogenetics of the alcohol dehydrogenase system

6 August 2017

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7 January 2021

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Regulation of the mammalian alcohol dehydrogenase genes

7 January 2021

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Organization of six functional mouse alcohol dehydrogenase genes on two overlapping bacterial artificial chromosomes

7 January 2021

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Alcohol and aldehyde dehydrogenases in human esophagus: comparison with the stomach enzyme activities

7 January 2021

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Expression and activities of class IV alcohol dehydrogenase and class III aldehyde dehydrogenase in human mouth

7 January 2021

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Genetic polymorphism and activities of human colon alcohol and aldehyde dehydrogenases: no gender and age differences

7 January 2021

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Alcohol dehydrogenase in human tissues: localisation of transcripts coding for five classes of the enzyme.

7 January 2021

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Human stomach alcohol and aldehyde dehydrogenases: comparison of expression pattern and activities in alimentary tract.

7 January 2021

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Lack of alcohol dehydrogenase isoenzyme activities in the stomach of Japanese subjects

7 January 2021

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Ethnic differences in gastric sigma-alcohol dehydrogenase activity and ethanol first-pass metabolism

7 January 2021

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Regulation of human alcohol dehydrogenase gene ADH7: importance of an AP-1 site

7 January 2021

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Alcohol dehydrogenase of human and rat blood vessels. Role in ethanol metabolism.

7 January 2021

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Class IV alcohol/retinol dehydrogenase localization in epidermal basal layer: potential site of retinoic acid synthesis during skin development

7 January 2021

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Regional distribution of mammalian corneal aldehyde dehydrogenase and alcohol dehydrogenase

7 January 2021

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Regional restriction of alcohol/retinol dehydrogenases along the mouse gastrointestinal epithelium

7 January 2021

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Localization of class I and class IV alcohol dehydrogenases in mouse testis and epididymis: potential retinol dehydrogenases for endogenous retinoic acid synthesis

7 January 2021

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Expression patterns of class I and class IV alcohol dehydrogenase genes in developing epithelia suggest a role for alcohol dehydrogenase in local retinoic acid synthesis

7 January 2021

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Expression, activities, and kinetic mechanism of human stomach alcohol dehydrogenase. Inference for first-pass metabolism of ethanol in mammals

7 January 2021

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Contribution to first-pass metabolism of ethanol and inhibition by ethanol for retinol oxidation in human alcohol dehydrogenase family--implications for etiology of fetal alcohol syndrome and alcohol-related diseases

7 January 2021

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Retinoids in embryonal development

7 January 2021

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Retinoic acid synthesis in mouse embryos during gastrulation and craniofacial development linked to class IV alcohol dehydrogenase gene expression

7 January 2021

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Initiation of retinoid signaling in primitive streak mouse embryos: spatiotemporal expression patterns of receptors and metabolic enzymes for ligand synthesis

7 January 2021

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Impaired retinol utilization in Adh4 alcohol dehydrogenase mutant mice

7 January 2021

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Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice

7 January 2021

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Impaired locomotion and dopamine signaling in retinoid receptor mutant mice.

7 January 2021

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An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression

7 January 2021

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X-ray structure of human class IV sigmasigma alcohol dehydrogenase. Structural basis for substrate specificity

7 January 2021

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cDNA sequence and catalytic properties of a chick embryo alcohol dehydrogenase that oxidizes retinol and 3beta,5alpha-hydroxysteroids

7 January 2021

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Molecular modelling of human gastric alcohol dehydrogenase (class IV) and substrate docking: differences towards the classical liver enzyme (class I)

7 January 2021

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Molecular docking studies on interaction of diverse retinol structures with human alcohol dehydrogenases predict a broad role in retinoid ligand synthesis

7 January 2021

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Molecular basis for differential substrate specificity in class IV alcohol dehydrogenases: a conserved function in retinoid metabolism but not in ethanol oxidation

7 January 2021

1 reference

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PRODUCT INHIBITION STUDIES ON YEAST AND LIVER ALCOHOL DEHYDROGENASES

7 January 2021

1 reference

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Kinetic mechanism of human class IV alcohol dehydrogenase functioning as retinol dehydrogenase

7 January 2021

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Genetic dissection of retinoid dehydrogenases

7 January 2021

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Alcohol, vitamin A, and beta-carotene: adverse interactions, including hepatotoxicity and carcinogenicity

7 January 2021

1 reference

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Chronic alcohol intake reduces retinoic acid concentration and enhances AP-1 (c-Jun and c-Fos) expression in rat liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900167-9

High blood alcohol levels in women. The role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism

7 January 2021

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The time-course of the effects of ethanol on the redox and phosphorylation states of rat liver

7 January 2021

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State of oxidation-reduction and state of binding in the cytosolic NADH-system as disclosed by equilibration with extracellular lactate-pyruvate in hemoglobin-free perfused rat liver

7 January 2021

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Rate-limiting factors in ethanol oxidation by isolated rat-liver parenchymal cells. Effect of ethanol concentration, fructose, pyruvate and pyrazole.

7 January 2021

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Identification of endogenous retinoids, enzymes, binding proteins, and receptors during early postimplantation development in mouse: important role of retinal dehydrogenase type 2 in synthesis of all-trans-retinoic acid

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900167-9

Mouse alcohol dehydrogenase 4: kinetic mechanism, substrate specificity and simulation of effects of ethanol on retinoid metabolism

7 January 2021

1 reference

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10.1016/S0009-2797(02)00167-9

7 January 2021

Identifiers

DOI

1 reference

6 August 2017

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