(Q35077861)

English

Expansion of CD27high plasmablasts in transverse myelitis patients that utilize VH4 and JH6 genes and undergo extensive somatic hypermutation.

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28 February 2020

Expansion of CD27high plasmablasts in transverse myelitis patients that utilize VH4 and JH6 genes and undergo extensive somatic hypermutation (English)

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28 February 2020

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28 February 2020

Benjamin M. Greenberg

9

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28 February 2020

author name string

A J Ligocki

1

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28 February 2020

W H Rounds

2

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28 February 2020

E M Cameron

3

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28 February 2020

C T Harp

4

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28 February 2020

E M Frohman

5

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28 February 2020

A M Courtney

6

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28 February 2020

L G Cowell

8

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28 February 2020

N L Monson

10

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28 February 2020

publication date

18 April 2013

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28 February 2020

Genes and Immunity

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28 February 2020

14

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28 February 2020

5

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28 February 2020

291-301

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28 February 2020

B cell exchange across the blood-brain barrier in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Plasmablast frequency and trafficking receptor expression are altered in pediatric ulcerative colitis

1 reference

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8 July 2018

B-cell numbers and phenotype at clinical relapse following rituximab therapy differ in SLE patients according to anti-dsDNA antibody levels

1 reference

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8 July 2018

Assessing the value of spinal cord lesions in predicting development of multiple sclerosis in patients with clinically isolated syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Blood memory B cells are disturbed and predict the response to rituximab in patients with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Alternative mechanisms of receptor editing in autoreactive B cells

1 reference

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8 July 2018

Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Brainstem lesions in clinically isolated syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Significantly higher percentage of circulating CD27(high) plasma cells in systemic lupus erythematosus patients with infection than with disease flare-up

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

A unique antibody gene signature is prevalent in the central nervous system of patients with multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Depletion of B lymphocytes from cerebral perivascular spaces by rituximab

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Potential of a unique antibody gene signature to predict conversion to clinically definite multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

CSF IgG heavy-chain bias in patients at the time of a clinically isolated syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

B-cell depletion with rituximab in relapsing-remitting multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Evidence for preferential Ig gene usage and differential TdT and exonuclease activities in human naïve and memory B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Cerebrospinal fluid B cells from multiple sclerosis patients are subject to normal germinal center selection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Rituximab reduces B cells and T cells in cerebrospinal fluid of multiple sclerosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

AN ELECTROPHORETIC STUDY OF THE PROTEIN COMPONENTS IN CEREBROSPINAL FLUID AND THEIR RELATIONSHIP TO THE SERUM PROTEINS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Multiple sclerosis--the plaque and its pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Immune surveillance of the human central nervous system (CNS): different migration pathways of immune cells through the blood-brain barrier and blood-cerebrospinal fluid barrier in healthy persons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

B-cell differentiation in the CNS of patients with multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Clinically isolated syndromes suggestive of multiple sclerosis, part I: natural history, pathogenesis, diagnosis, and prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Cortical lesions in multiple sclerosis: combined postmortem MR imaging and histopathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

CSF B-cell expansion in opsoclonus-myoclonus syndrome: a biomarker of disease activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Predominant autoantibody production by early human B cell precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Immunopathogenesis of acute transverse myelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Patterns of cerebrospinal fluid pathology correlate with disease progression in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

IMGT, the international ImMunoGeneTics database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Immunoglobulin heavy chain variable region gene replacement As a mechanism for receptor revision in rheumatoid arthritis synovial tissue B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Multiple sclerosis: in situ evidence for antibody- and complement-mediated demyelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Restricted use of VH4 germline segments in an acute multiple sclerosis brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Axonal transection in the lesions of multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Human autoantibody recognition of DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

Immunoglobulin-containing cells in multiple-sclerosis plaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

8 July 2018

High-throughput antibody sequencing reveals genetic evidence of global regulation of the naïve and memory repertoires that extends across individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Axonal and oligodendrocyte-localized IgM and IgG deposits in MS lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Immunological markers of optimal response to natalizumab in multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Natalizumab treatment perturbs memory- and marginal zone-like B-cell homing in secondary lymphoid organs in multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

A plasmablast biomarker for nonresponse to antibody therapy to CD20 in rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

B cells undergo unique compartmentalized redistribution in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Repeated treatment with rituximab based on the assessment of peripheral circulating memory B cells in patients with relapsing neuromyelitis optica over 2 years

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

B cell biomarkers of rituximab responses in systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Somatic hypermutation and antigen-driven selection of B cells are altered in autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Central memory CD4+ T cells dominate the normal cerebrospinal fluid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Assessment of outcome predictors in first-episode acute myelitis: a retrospective study of 53 cases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Value of the peripheral blood B-cells subsets in patients with ankylosing spondylitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Memory and naïve B-cell subsets in patients with multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Quantitative estimation of the albumin and gamma globulin in normal and pathologic cerebrospinal fluid by immunochemical methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

B and T cell imbalances in CSF of patients with Hu-antibody associated PNS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Accumulation of class switched IgD-IgM- memory B cells in the cerebrospinal fluid during neuroinflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Short-lived plasma blasts are the main B cell effector subset during the course of multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

A study of the crystalline albumin, gamma globulin and total protein in the cerebrospinal fluid of 100 cases of multiple sclerosis and in other diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Contribution of Vh gene replacement to the primary B cell repertoire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Correlation between circulating CD27high plasma cells and disease activity in patients with systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Demyelination in primate autoimmune encephalomyelitis and acute multiple sclerosis lesions: a case for antigen-specific antibody mediation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Identification of autoantibodies associated with myelin damage in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Lymphocyte phenotype and subset distribution in normal cerebrospinal fluid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326094

27 September 2018

A three-year, multi-parametric MRI study in patients at presentation with CIS

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2013.18

21 January 2018

Most Patients With Multiple Sclerosis or a Clinically Isolated Demyelinating Syndrome Should Be Treated at the Time of Diagnosis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2013.18

21 January 2018

Longitudinal studies of the association between peripheral CD27++ plasma cells and systemic lupus erythematosus disease activity: preliminary results

1 reference

https://pubmed.ncbi.nlm.nih.gov/23594958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diminished peripheral blood memory B cells and accumulation of memory B cells in the salivary glands of patients with Sjögren's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23594958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor revision and atypical mutational characteristics in clonally expanded B cells from the cerebrospinal fluid of recently diagnosed multiple sclerosis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23594958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paraneoplastic neurological disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/23594958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/23594958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VH4 gene segments dominate the intrathecal humoral immune response in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23594958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23594958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous cytometric analysis of (auto)antigen-reactive T and B cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23594958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23594958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical, magnetic resonance imaging, cerebrospinal fluid and electrophysiological characteristics of the earliest multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23594958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primed status of transitional B cells associated with their presence in the cerebrospinal fluid in early phases of multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23594958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/GENE.2013.18

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23594958%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23594958%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23594958%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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