(Q35079447)

6 August 2017

1 reference

title

The many forks in FOXO's road (English)

1 reference

6 August 2017

Hien Tran

1

1 reference

6 August 2017

Anne Brunet

series ordinal

2

1 reference

6 August 2017

Eric C Griffith

series ordinal

3

1 reference

6 August 2017

Michael E Greenberg

series ordinal

4

1 reference

6 August 2017

4 March 2003

1 reference

Science's STKE : signal transduction knowledge environment

6 August 2017

1 reference

6 August 2017

2003

1 reference

6 August 2017

RE5

1 reference

6 August 2017

172

1 reference

The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo

6 August 2017

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The fork head domain: a novel DNA binding motif of eukaryotic transcription factors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Signalling through the lipid products of phosphoinositide-3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Role of translocation in the activation and function of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Direct control of the Forkhead transcription factor AFX by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Negative regulation of the forkhead transcription factor FKHR by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Cell cycle and hormonal control of nuclear-cytoplasmic localization of the serum- and glucocorticoid-inducible protein kinase, Sgk, in mammary tumor cells. A novel convergence point of anti-proliferative and proliferative cell signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Epithelial sodium channel regulated by aldosterone-induced protein sgk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Regulation of the Forkhead transcription factor AFX by Ral-dependent phosphorylation of threonines 447 and 451

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The structural basis for 14-3-3:phosphopeptide binding specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Nuclear transport and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Forkhead transcription factors contribute to execution of the mitotic programme in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Ras and Rho regulation of the cell cycle and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Forkhead family transcription factor FKHRL1 is expressed in human megakaryocytes. Regulation of cell cycling as a downstream molecule of thrombopoietin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

p27(Kip1): regulation and function of a haploinsufficient tumor suppressor and its misregulation in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

FOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Regulation of APC activity by phosphorylation and regulatory factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Regulation of the APC and the exit from mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Polo-like kinases: a team that plays throughout mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Aging and resistance to oxidative damage in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-C and clk-1 mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Understanding Ras: 'it ain't over 'til it's over'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Pten is essential for embryonic development and tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Structural characterization of the FKHR gene and its rearrangement in alveolar rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Genetic pathways that regulate ageing in model organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Extended longevity in mice lacking the insulin receptor in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

A C. elegans mutant that lives twice as long as wild type

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Oxidants, oxidative stress and the biology of ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The p66shc adaptor protein controls oxidative stress response and life span in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Regulation of glucose-6-phosphatase gene expression by protein kinase Balpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

Gene- and activation-specific mechanisms for insulin inhibition of basal and glucocorticoid-induced insulin-like growth factor binding protein-1 and phosphoenolpyruvate carboxykinase transcription. Roles of forkhead and insulin response sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2003.172.RE5

10.1126/STKE.2003.172.RE5

21 January 2018

Identifiers

DOI

1 reference

6 August 2017

1 reference