(Q35081895)

6 August 2017

title

Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice (English)

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6 August 2017

1 reference

Susan A Charman

21

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Diana Caridha

5

object named as

Diana Caridha

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6 August 2017

Geoffrey S Dow

1

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6 August 2017

Erin Milner

2

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6 August 2017

Ian Bathurst

3

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6 August 2017

Jayendra Bhonsle

4

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6 August 2017

Sean Gardner

6

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6 August 2017

Lucia Gerena

7

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6 August 2017

Michael Kozar

8

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6 August 2017

Charlotte Lanteri

9

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6 August 2017

Anne Mannila

10

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6 August 2017

William McCalmont

11

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6 August 2017

Jay Moon

12

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6 August 2017

Kevin D Read

13

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6 August 2017

Suzanne Norval

14

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6 August 2017

Norma Roncal

15

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6 August 2017

David M Shackleford

16

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6 August 2017

Jason Sousa

17

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6 August 2017

Jessica Steuten

18

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6 August 2017

Karen L White

19

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6 August 2017

Qiang Zeng

20

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6 August 2017

publication date

6 June 2011

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6 August 2017

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6 August 2017

volume

10

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6 August 2017

page(s)

150

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Creative Commons Attribution 2.0 Generic

6 August 2017

copyright license

start time

6 June 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

How to improve R&D productivity: the pharmaceutical industry's grand challenge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

Structure-activity relationships amongst 4-position quinoline methanol antimalarials that inhibit the growth of drug sensitive and resistant strains of Plasmodium falciparum

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

Clinical development of new prophylactic antimalarial drugs after the 5th Amendment to the Declaration of Helsinki

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

Mefloquine-induced disruption of calcium homeostasis in mammalian cells is similar to that induced by ionomycin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

Central nervous system drug disposition: the relationship between in situ brain permeability and brain free fraction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

The IPTi Consortium: research for policy and action

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

Mefloquine induces dose-related neurological effects in a rat model

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

Unexpected frequency, duration and spectrum of adverse events after therapeutic dose of mefloquine in healthy adults

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

Atovaquone-proguanil versus mefloquine for malaria prophylaxis in nonimmune travelers: results from a randomized, double-blind study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

Drug-like properties and the causes of poor solubility and poor permeability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

In vitro activities of and mechanisms of resistance to antifol antimalarial drugs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

A nuclear magnetic resonance study of the interactions of the antimalarials chloroquine, quinacrine, quinine and mefloquine with dipalmitoylphosphatidylcholine bilayers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

Drug-free holidays: pre-travel versus during travel malaria chemoprophylaxis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

Influence of nonspecific brain and plasma binding on CNS exposure: implications for rational drug discovery.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128011

Thermodynamics of partitioning of the antimalarial drug mefloquine in phospholipid bilayers and bulk solvents

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21645370

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1475-2875-10-150

1 reference

Dimensions Publication ID

6 August 2017

0 references

1 reference

6 August 2017

1 reference