(Q35083415)

English

Up-regulation of the redox mediators thioredoxin and apurinic/apyrimidinic excision (APE)/Ref-1 in hypoxic microregions of invasive cervical carcinomas, mapped using multispectral, wide-field fluorescence image analysis

scientific article published in February 2004

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Up-regulation of the redox mediators thioredoxin and apurinic/apyrimidinic excision (APE)/Ref-1 in hypoxic microregions of invasive cervical carcinomas, mapped using multispectral, wide-field fluorescence image analysis (English)

1 reference

Europe PubMed Central

6 August 2017

0 references

0 references

object named as

Anthony Fyles

7

0 references

object named as

David Hedley

1

0 references

Michael Milosevic

object named as

Michael Milosevic

8

0 references

author name string

Melania Pintilie

2

1 reference

Europe PubMed Central

6 August 2017

Jennifer Woo

3

1 reference

Europe PubMed Central

6 August 2017

Trudey Nicklee

4

1 reference

Europe PubMed Central

6 August 2017

Andrew Morrison

5

1 reference

Europe PubMed Central

6 August 2017

Diana Birle

6

1 reference

Europe PubMed Central

6 August 2017

Richard Hill

9

1 reference

Europe PubMed Central

6 August 2017

language of work or name

0 references

publication date

1 February 2004

1 reference

Europe PubMed Central

6 August 2017

The American Journal of Pathology

1 reference

Europe PubMed Central

6 August 2017

164

1 reference

Europe PubMed Central

6 August 2017

2

1 reference

Europe PubMed Central

6 August 2017

557-565

1 reference

Europe PubMed Central

6 August 2017

Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

GLUT-1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix: relationship to pimonidazole binding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Modulation of cell death in the tumor microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Structure, mechanism and regulation of peroxiredoxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Preconditioning-mediated neuroprotection: role of nitric oxide, cGMP, and new protein expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Hypoxia--a key regulatory factor in tumour growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Biological consequences of tumor hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Up-regulation of thioredoxin and thioredoxin reductase in human malignant pleural mesothelioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Properties and biological activities of thioredoxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

From cytoprotection to tumor suppression: the multifactorial role of peroxiredoxins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Antioxidant function of thioredoxin and glutaredoxin systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Hypoxia-inducible expression of tumor-associated carbonic anhydrases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Going APE over ref-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Physiological functions of thioredoxin and thioredoxin reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Microenvironment-induced cancer metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Thioredoxin reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Levels of the DNA repair enzyme human apurinic/apyrimidinic endonuclease (APE1, APEX, Ref-1) are associated with the intrinsic radiosensitivity of cervical cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Apurinic endonuclease (Ref-1) is induced in mammalian cells by oxidative stress and involved in clastogenic adaptation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Redox regulation of cellular activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Redox control of resistance to cis-diamminedichloroplatinum (II) (CDDP): protective effect of human thioredoxin against CDDP-induced cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

8 July 2018

Carbonic anhydrase IX expression, hypoxia, and prognosis in patients with uterine cervical carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

27 September 2018

Hypoxia-ischemia induces thioredoxin expression and nitrotyrosine formation in new-born rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

27 September 2018

The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

27 September 2018

Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

27 September 2018

Apurinic/apyrimidinic endonuclease activity is elevated in human adult gliomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

27 September 2018

Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

27 September 2018

Interstitial fluid pressure predicts survival in patients with cervix cancer independent of clinical prognostic factors and tumor oxygen measurements.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

27 September 2018

Nuclear expression of human apurinic/apyrimidinic endonuclease (HAP1/Ref-1) in head-and-neck cancer is associated with resistance to chemoradiotherapy and poor outcome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

27 September 2018

Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

27 September 2018

Thioredoxin-dependent redox regulation of p53-mediated p21 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

27 September 2018

Expression of nuclear redox factor ref-1 in the rat hippocampus following global ischemia induced by cardiac arrest.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

27 September 2018

Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1602260

16 November 2018

AP endonucleases and the many functions of Ref-1

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963145-8

7 January 2021

Improved treatment for cervical cancer--concurrent chemotherapy and radiotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963145-8

7 January 2021

Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963145-8

7 January 2021

Antioxidant function of the mitochondrial protein SP-22 in the cardiovascular system

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963145-8

7 January 2021

Alterations in the expression of the DNA repair/redox enzyme APE/ref-1 in epithelial ovarian cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/14742261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Widespread expression of thioredoxin and thioredoxin reductase in non-small cell lung carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14742261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA repair-redox enzyme apurinic endonuclease in cervical cancer: evaluation of redox control of HIF-1alpha and prognostic significance

1 reference

https://pubmed.ncbi.nlm.nih.gov/14742261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioredoxin expression is associated with lymph node status and prognosis in early operable non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/14742261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14742261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14742261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix

1 reference

https://pubmed.ncbi.nlm.nih.gov/14742261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/S0002-9440(10)63145-8

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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