(Q35083765)

6 August 2017

Metabolic pathways of 7,12-dimethylbenz[a]anthracene in hepatic microsomes (English)

1 reference

6 August 2017

S. K. Yang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A809767

30 July 2022

W. V. Dower

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A809767

30 July 2022

language of work or name

English

0 references

publication date

1 July 1975

1 reference

full work available at URL

6 August 2017

https://europepmc.org/articles/PMC432817

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A809767

https://europepmc.org/articles/PMC432817?pdf=render

30 July 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A809767

Proceedings of the National Academy of Sciences of the United States of America

30 July 2022

published in

1 reference

6 August 2017

72

1 reference

6 August 2017

7

1 reference

6 August 2017

2601-2605

1 reference

Selective adrenal necrosis and apoplexy induced by 7, 12-dimethylbenz(a)anthracene

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

METABOLISM OF POLYCYCLIC COMPOUNDS. THE METABOLISM OF 7,12-DIMETHYLBENZ[α]ANTHRACENE BY RAT-LIVER HOMOGENATES

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

INDUCED PROTECTION OF ADRENAL CORTEX AGAINST 7,12-DIMETHYLBENZ(ALPHA)ANTHRACENE. INFLUENCE OF ETHIONINE. INDUCTION OF MENADIONE REDUCTASE. INCORPORATION OF THYMIDINE-H3.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

The effect of pretreatment with adrenal-protecting compounds on the metabolism of 7,12-dimethylbenz[a]anthracene and related compounds by rat-liver homogenates

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

The metabolism of 7- and 12-methylbenz[a]-anthracene and their derivatives

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Studies on the metabolism of 7-methylbenz-[a]anthracene and 7,12-dimethylbenz[a]-anthracene and its hydroxymethyl derivatives in rat liver and adrenal homogenates

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Mutagenicity to mammalian cells of epoxides and other derivatives of polycyclic hydrocarbons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Reactivity of the K-region epoxides of some polycyclic hydrocarbons towards the nucleic acids and proteins of BHK 21 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Malignant transformation of cells derived from mouse prostate by epoxides and other derivatives of polycyclic hydrocarbons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different species, tissues, strains, and developmental and hormonal states.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Quantitative studies on the malignant transformation of mouse prostate cells by carcinogenic hydrocarbonsin vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Arene oxides: a new aspect of drug metabolism.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Malignant transformationin vitro of mouse fibroblasts by 7, 12-dimethylbenz(A)anthracene and 7-hydroxymethylbenz(A)anthracene and by their K-region derivatives

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Mammalian Epoxide Hydrases: Inducible Enzymes Catalysing the Inactivation of Carcinogenic and Cytotoxic Metabolites Derived from Aromatic and Olefinic Compounds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Epoxides of Carcinogenic Polycyclic Hydrocarbons Are Frameshift Mutagens

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Metabolism of 7,12-dimethylbenz(a)anthracene by hamster liver homogenates.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

An epoxide is an intermediate in the microsomal metabolism of the chemical carcinogen, dibenz(a,h)anthracene.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Substrate-inducible microsomal aryl hydroxylase in mammalian cell culture. I. Assay and properties of induced enzyme

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Pharmacological implications of microsomal enzyme induction.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Carcinogens, enzyme induction, and gene action

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Arene oxides and the NIH shift: the metabolism, toxicity and carcinogenicity of aromatic compounds.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Transformation of hamster embryo cells by epoxides and other derivatives of polycyclic hydrocarbons.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

In vitro transformation of rodent cells by K-region derivatives of polycyclic hydrocarbons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Comparison of the efficacy of pretreatment protection against adrenal necrosis induced by 7-hydroxymethyl-12-methylbenz(a)anthracene and by 7-methyl-12-methylbenz(a)anthracene in rats.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Mammary cancer induced by a single feeding of polymucular hydrocarbons, and its suppression.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Quantitative aspects of the metabolism of 7, 12-dimethylbenz[a]anthracene by liver homogenates from animals of different age, sex and species

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Mutagenicity of epoxides of polycyclic hydrocarbons correlates with carcinogenicity of parent hydrocarbons.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=432817

Induction of Adrenal Damage and Cancer with Metabolites of 7,12-Dimethylbenz(a)Anthracene

27 September 2018

1 reference

12 December 2020

The formation of "K-region" epoxides as hepatic microsomal metabolites of 7-methylbenz(a)anthracene and 7,12-dimethylbenz(a)anthracene and their 7-hydroxymethyl derivatives

1 reference

12 December 2020

Stimulatory effect of polycyclic hydrocarbons and aromatic azo derivatives on the metabolism of 7,12-dimethylbenz(alpha)anthracene

1 reference

12 December 2020

Induction of hepatic 7,12-dimethylbenz(alpha)anthracene metabolism by polycyclic aromatic hydrocarbons and aromatic azo derivatives

1 reference

12 December 2020

High-pressure liquid chromatographic analysis of benzo(alpha)pyrene metabolism and covalent binding and the mechanism of action of 7,8-benzoflavone and 1,2-epoxy-3,3,3-trichloropropane

1 reference

12 December 2020

Cell-mediated mutagenesis of mammalian cells with chemical carcinogens

1 reference

12 December 2020

Formation of glutathione conjugates as metabolites of 7,12-dimethylbenz-[a] anthracene by rat-liver homogenates

1 reference

12 December 2020

K-region and non-K-region metabolism of benzo(a)pyrene by rat liver microsomes

1 reference

12 December 2020

Formation of K-region epoxides as microsomal metabolites of pyrene and benzo(a)pyrene

1 reference

12 December 2020

Qualitative and quantitative studies on the metabolism of a series of aromatic hydrocarbons by rat-liver preparations

1 reference

12 December 2020

Dimethylbenzanthracene Tumorigenesis and Aryl Hydrocarbon Hydroxylase in Mouse Skin: Inhibition by 7,8-Benzoflavone

1 reference

12 December 2020

1,2-Naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene. V

1 reference

12 December 2020

Syntheses of Metabolites of 7,12-Dimethylbenz[a]anthracene. 4-Hydroxy-7,12-dimethylbenz[a]anthracene, 7-Hydroxymethyl-12-methylbenz[a]anthracene, Their Methyl Ethers, and Acetoxy Derivatives

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.72.7.2601

1 reference

6 August 2017

0 references

1 reference

6 August 2017

1 reference