(Q35084061)

6 August 2017

title

Targeting a c-MYC G-quadruplex DNA with a fragment library (English)

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6 August 2017

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G-quadruplex DNA

3 January 2024

Hamid R Nasiri

1

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6 August 2017

Neil M Bell

2

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6 August 2017

Keith I E McLuckie

3

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6 August 2017

Jarmila Husby

4

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6 August 2017

Chris Abell

5

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6 August 2017

Stephen Neidle

6

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6 August 2017

Shankar Balasubramanian

7

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6 August 2017

language of work or name

English

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publication date

1 February 2014

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6 August 2017

published in

Chemical Communications

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6 August 2017

volume

50

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6 August 2017

issue

14

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6 August 2017

page(s)

1704-1707

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Monovalent cation-induced structure of telomeric DNA: the G-quartet model

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine-guanine base pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

Solution structure of a parallel-stranded G-quadruplex DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

Prevalence of quadruplexes in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

Highly prevalent putative quadruplex sequence motifs in human DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

G-quadruplexes in promoters throughout the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

G-quadruplexes: the beginning and end of UTRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

Small-molecule-induced DNA damage identifies alternative DNA structures in human genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

Putative DNA quadruplex formation within the human c-kit oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

Drug targeting of the c-MYC promoter to repress gene expression via a G-quadruplex silencer element

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

A small molecule that disrupts G-quadruplex DNA structure and enhances gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

G-quadruplex nucleic acids as therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

Anticancer activity of CX-3543: a direct inhibitor of rRNA biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

A fragment-based approach to identifying ligands for riboswitches

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

Thiazole orange as the fluorescent intercalator in a high resolution fid assay for determining DNA binding affinity and sequence selectivity of small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

A ‘Rule of Three’ for fragment-based lead discovery?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

Anticancer activity and cellular repression of c-MYC by the G-quadruplex-stabilizing 11-piperazinylquindoline is not dependent on direct targeting of the G-quadruplex in the c-MYC promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

A sodium-potassium switch in the formation of four-stranded G4-DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC48390H

21 January 2018

Identifiers

DOI

10.1039/C3CC48390H

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6 August 2017

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