(Q35085094)

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Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21576240%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells (English)

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1 February 2020

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1 February 2020

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Ravinder Tammali

1

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1 February 2020

Ashish Saxena

2

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1 February 2020

Satish K Srivastava

3

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1 February 2020

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16 May 2011

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1 February 2020

Journal of Biological Chemistry

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1 February 2020

286

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1 February 2020

27

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1 February 2020

24089-24100

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1 February 2020

A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis

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8 July 2018

Inhibition of angiogenesis by quercetin in tamoxifen-resistant breast cancer cells

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Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells.

1 reference

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8 July 2018

Aldose reductase and cardiovascular diseases, creating human-like diabetic complications in an experimental model.

1 reference

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8 July 2018

Inhibition of aldose reductase prevents growth factor-induced G1-S phase transition through the AKT/phosphoinositide 3-kinase/E2F-1 pathway in human colon cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129190

8 July 2018

(-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cells

1 reference

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8 July 2018

Up-regulation of pro-inflammatory genes as adaptation to hypoxia in MCF-7 cells and in human mammary invasive carcinoma microenvironment

1 reference

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1 reference

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8 July 2018

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1 reference

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1 reference

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8 July 2018

Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formation

1 reference

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8 July 2018

Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells

1 reference

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8 July 2018

Resveratrol inhibits hypoxia-induced metastasis potential enhancement by restricting hypoxia-induced factor-1 alpha expression in colon carcinoma cells

1 reference

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8 July 2018

Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy

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8 July 2018

Hypoxia enhances LPA-induced HIF-1alpha and VEGF expression: their inhibition by resveratrol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129190

8 July 2018

Imatinib inhibits colorectal cancer cell growth and suppresses stromal-induced growth stimulation, MT1-MMP expression and pro-MMP2 activation.

1 reference

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8 July 2018

Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129190

8 July 2018

Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia

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Mitogenic responses of vascular smooth muscle cells to lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (HNE): role of aldose reductase-catalyzed reduction of the HNE-glutathione conjugates in regulating cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129190

8 July 2018

Natural product-based inhibitors of hypoxia-inducible factor-1 (HIF-1).

1 reference

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8 July 2018

From traditional Ayurvedic medicine to modern medicine: identification of therapeutic targets for suppression of inflammation and cancer.

1 reference

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8 July 2018

Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation

1 reference

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8 July 2018

Mechanisms of disease: Inflammatory mediators and cancer prevention

1 reference

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8 July 2018

A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression

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8 July 2018

A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129190

8 July 2018

Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options

1 reference

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8 July 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129190

8 July 2018

Arsenite induces HIF-1a and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells

1 reference

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1 reference

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Investigating hypoxic tumor physiology through gene expression patterns

1 reference

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8 July 2018

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1 reference

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8 July 2018

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1 reference

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8 July 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129190

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Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells.

1 reference

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1 reference

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21 January 2018

Aldose reductase regulates growth factor-induced cyclooxygenase-2 expression and prostaglandin E2 production in human colon cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.219733

21 January 2018

Aldose reductase inhibitor fidarestat prevents retinal oxidative stress and vascular endothelial growth factor overexpression in streptozotocin-diabetic rats.

1 reference

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21 January 2018

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1 reference

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21 January 2018

Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells

1 reference

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21 January 2018

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1 reference

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12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21576240

12 December 2020

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Curcumin inhibits hypoxia-induced angiogenesis via down-regulation of HIF-1

1 reference

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12 December 2020

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Aldose reductase inhibition: emerging drug target for the treatment of cardiovascular complications

1 reference

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12 December 2020

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Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/21576240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.219733

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21576240%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21576240%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21576240%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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