(Q35085222)

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Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

colon carcinoma

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

author name string

Quan Lin

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Raymond Lai

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Lucian R Chirieac

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Changping Li

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Vilmos A Thomazy

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Ioannis Grammatikakis

6

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

George Z Rassidakis

7

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Wei Zhang

8

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Yasushi Fujio

9

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Keita Kunisada

10

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Stanley R Hamilton

11

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Hesham M Amin

12

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Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

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publication date

1 October 2005

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

The American Journal of Pathology

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Europe PubMed Central

PubMed publication ID

6 August 2017

167

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

969-980

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Production of interleukin 15 by human colon cancer cells is associated with induction of mucosal hyperplasia, angiogenesis, and metastasis

1 reference

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8 July 2018

Fibronectin Protects Prostate Cancer Cells from Tumor Necrosis Factor-α-induced Apoptosis via the AKT/Survivin Pathway

1 reference

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8 July 2018

STAT proteins: From normal control of cellular events to tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

1 reference

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8 July 2018

Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck

1 reference

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8 July 2018

Cancer statistics, 2003.

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8 July 2018

Signal transducer and activator of transcription proteins in leukemias.

1 reference

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8 July 2018

Downregulation of survivin expression by induction of the effector cell protease receptor-1 reduces tumor growth potential and results in an increased sensitivity to anticancer agents in human colon cancer

1 reference

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8 July 2018

Opposite regulation of myc and p21waf1 transcription by STAT3 proteins

1 reference

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8 July 2018

Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

STAT3 down-regulates the expression of cyclin D during liver development

1 reference

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8 July 2018

Signaling through the JAK/STAT pathway, recent advances and future challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

JAKs, STATs and Src kinases in hematopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

Interleukin-7 receptor expression and activation in nonhaematopoietic neoplastic cell lines

1 reference

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8 July 2018

The molecular basis and potential role of survivin in cancer diagnosis and therapy

1 reference

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8 July 2018

Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3-activation, interleukin-2 receptor expression and growth of leukemic Sezary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

STAT proteins and transcriptional responses to extracellular signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

Butyrate metabolism upstream and downstream acetyl-CoA synthesis and growth control of human colon carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

STAT-signalling through the cytoplasmic compartment: consideration of a new paradigm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

Bcl-X(L) antisense sensitizes human colon cancer cell line to 5-fluorouracil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

The role of STATs in transcriptional control and their impact on cellular function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

beta-lapachone induces cell cycle arrest and apoptosis in human colon cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

Stat3 as an oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

Prognostic value of bcl-2 oncoprotein expression in stage II colon carcinoma

1 reference

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8 July 2018

Apoptosis of colorectal adenocarcinoma (COLO 201) by tumour necrosis factor-alpha (TNF-alpha) and/or interferon-gamma (IFN-gamma), resulting from down-modulation of Bcl-2 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

1 reference

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8 July 2018

Expression of Janus kinase 3 in human endothelial and other non-lymphoid and non-myeloid cells

1 reference

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8 July 2018

IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

Receptors for interleukin (IL)-4 do not associate with the common gamma chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

A kinase-deficient splice variant of the human JAK3 is expressed in hematopoietic and epithelial cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

8 July 2018

Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells

1 reference

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27 September 2018

Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

27 September 2018

Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of hu

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603671

27 September 2018

Src activation regulates anoikis in human colon tumor cell lines

1 reference

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Neuregulin-1 activates the JAK-STAT pathway and regulates lung epithelial cell proliferation.

1 reference

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1 reference

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Gamma interferon down-regulates Fer and induces its association with inactive Stat3 in colon carcinoma cells

1 reference

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STAT3 is constitutively activated in Hodgkin cell lines

1 reference

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Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

1 reference

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1 reference

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1 reference

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Tyrphostin AG490 selectively inhibits activation of the JAK3/STAT5/MAPK pathway and rejection of rat heart allografts

1 reference

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Comparison of effects of the tyrosine kinase inhibitors AG957, AG490, and STI571 on BCR-ABL--expressing cells, demonstrating synergy between AG490 and STI571.

1 reference

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1 reference

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1 reference

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7 January 2021

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1 reference

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7 January 2021

Identifiers

10.1016/S0002-9440(10)61187-X

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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