(Q73555967)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12818369%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells (English)

1 reference

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5 November 2019

1 reference

1 reference

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8

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5 November 2019

author name string

Manchao Zhang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12818369%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Hongpeng Liu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12818369%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Ribo Guo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12818369%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Yan Ling

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12818369%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Xiaojin Wu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12818369%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Bihua Li

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12818369%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Peter P Roller

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12818369%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Dajun Yang

9

1 reference

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5 November 2019

language of work or name

English

0 references

publication date

1 July 2003

1 reference

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5 November 2019

published in

Biochemical Pharmacology

1 reference

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5 November 2019

volume

66

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12818369%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

issue

1

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5 November 2019

page(s)

93-103

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12818369%20AND%20SRC:MED&resulttype=core&format=json

An overview of the clinical pharmacology and therapeutic potential of gossypol as a male contraceptive agent and in gynaecological disease

5 November 2019

cites work

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Gossypol inhibits Ehrlich ascites tumor cell proliferation

7 January 2021

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Antitumor effects of gossypol on murine tumors

7 January 2021

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Genotoxic effects of gossypol acetic acid on cultured murine erythroleukemia cells

7 January 2021

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In vitro and in vivo cytotoxicity of gossypol against central nervous system tumor cell lines

7 January 2021

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Antiproliferative activity of gossypol and gossypolone on human breast cancer cells

7 January 2021

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Gossypol inhibits basal and estrogen-stimulated DNA synthesis in human breast carcinoma cells

7 January 2021

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Modulation of resistance to alkylating agents in cancer cell by gossypol enantiomers

7 January 2021

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Cytotoxicity of gossypol enantiomers and its quinone metabolite gossypolone in melanoma cell lines.

7 January 2021

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Gossypol induced apoptosis in the human promyelocytic leukemia cell line HL 60.

7 January 2021

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Cytotoxic effect of gossypol on colon carcinoma cells

7 January 2021

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Selective toxicity of gossypol against epithelial tumors and its detection by magnetic resonance spectroscopy

7 January 2021

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Gossypol effects on cultured normal and malignant melanocytes

7 January 2021

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Antiproliferative effect of gossypol and its optical isomers on human reproductive cancer cell lines

7 January 2021

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Gossypol effects on endothelial cells and tumor blood flow

7 January 2021

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Presence of antitumor activities in the milk collected from gossypol-treated dairy cows

7 January 2021

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Synthesis and cytotoxicity of gossypol related compounds

7 January 2021

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Gossypol-induced DNA breaks in rat lymphocytes are secondary to cytotoxicity

7 January 2021

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Developing gossypol derivatives with enhanced antitumor activity

7 January 2021

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Stereo-specific cytotoxic effects of gossypol enantiomers and gossypolone in tumour cell lines

7 January 2021

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Structure-activity studies on gossypol in tumor cell lines

7 January 2021

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Gossypol: prototype of inhibitors targeted to dinucleotide folds

7 January 2021

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Gossypol treatment of recurrent adult malignant gliomas

7 January 2021

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Oral gossypol in the treatment of patients with refractory metastatic breast cancer: a phase I/II clinical trial.

7 January 2021

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A preliminary clinical study of gossypol in advanced human cancer

7 January 2021

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Gossypol-induced apoptotic DNA fragmentation correlates with inhibited protein kinase C activity in spermatocytes

7 January 2021

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Studies on the possible role of protein kinase C in the prolactin regulation of cell replication in Nb2 node lymphoma cells.

7 January 2021

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Gossypol, a potent inhibitor of arachidonate 5- and 12-lipoxygenases

7 January 2021

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c-fos protein expression in apoptotic rat spermatocytes induced by gossypol

7 January 2021

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Biphasic c-Myc protein expression during gossypol-induced apoptosis in rat spermatocytes

7 January 2021

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Inhibition of human prostate cancer cells growth by gossypol is associated with stimulation of transforming growth factor-beta

7 January 2021

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Gossypol inhibition of mitosis, cyclin D1 and Rb protein in human mammary cancer cells and cyclin-D1 transfected human fibrosarcoma cells

7 January 2021

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Colorimetric determination of inhibition of hematopoietic progenitor cells in soft agar

7 January 2021

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

7 January 2021

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Executionary pathway for apoptosis: lessons from mutant mice

7 January 2021

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Dissecting the pathways to death

7 January 2021

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Inhibition of apoptosis-associated DNA fragmentation activity in nonapoptotic cells: the role of DNA fragmentation factor-45 (DFF45/ICAD).

7 January 2021

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Involvement of PARP and poly(ADP-ribosyl)ation in the early stages of apoptosis and DNA replication

7 January 2021

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Structural rearrangement of the retinoblastoma gene in human breast carcinoma

7 January 2021

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RB and the cell cycle: entrance or exit?

7 January 2021

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Bcl-2 gene family and related proteins in mammary gland involution and breast cancer

7 January 2021

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Expression of multiple apoptosis-regulatory genes in human breast cancer cell lines and primary tumors

7 January 2021

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Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

7 January 2021

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

7 January 2021

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Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions

7 January 2021

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Role of Bcl-2, Bax, and Bak in spontaneous apoptosis and proliferation in neuroendocrine lung tumors: immunohistochemical study

7 January 2021

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Adenovirus-mediated Bak gene transfer induces apoptosis in mesothelioma cell lines

7 January 2021

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A role for mitochondrial Bak in apoptotic response to anticancer drugs

7 January 2021

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Mitochondria and apoptosis

7 January 2021

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Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes

7 January 2021

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Aspirin induces apoptosis through release of cytochrome c from mitochondria

7 January 2021

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Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1

7 January 2021

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900248-X

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900248-X

Apaf-1/cytochrome c-independent and Smac-dependent induction of apoptosis in multiple myeloma (MM) cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900248-X

Mitochondrial release of apoptosis-inducing factor and cytochrome c during smooth muscle cell apoptosis

7 January 2021

1 reference

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Relocalization of apoptosis-inducing factor in photoreceptor apoptosis induced by retinal detachment in vivo

7 January 2021

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Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

7 January 2021

1 reference

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Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells

7 January 2021

1 reference

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Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells.

7 January 2021

1 reference

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10.1016/S0006-2952(03)00248-X

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12818369%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference