(Q35086814)

6 August 2017

title

Spontaneously diabetic Ins2(+/Akita):apoE-deficient mice exhibit exaggerated hypercholesterolemia and atherosclerosis (English)

1 reference

6 August 2017

0 references

1 reference

John Y Jun

1

1 reference

6 August 2017

Zhexi Ma

series ordinal

2

1 reference

6 August 2017

Lakshman Segar

series ordinal

3

1 reference

6 August 2017

publication date

29 March 2011

1 reference

American Journal of Physiology - Endocrinology and Metabolism

6 August 2017

published in

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6 August 2017

volume

301

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6 August 2017

issue

1

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6 August 2017

page(s)

E145-54

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describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3129838/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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8 July 2018

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Impact of genetic background on nephropathy in diabetic mice

8 July 2018

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8 July 2018

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8 July 2018

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The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells.

8 July 2018

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8 July 2018

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8 July 2018

1 reference

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8 July 2018

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8 July 2018

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Magnitude and determinants of coronary artery disease in juvenile-onset, insulin-dependent diabetes mellitus

8 July 2018

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8 July 2018

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Impaired hepatic apolipoprotein B and E translation in streptozotocin diabetic rats

8 July 2018

1 reference

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Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

8 July 2018

1 reference

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Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

8 July 2018

1 reference

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8 July 2018

1 reference

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Lipolysis stimulated lipoprotein receptor: a novel molecular link between hyperlipidemia, weight gain, and atherosclerosis in mice

27 September 2018

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Decreased lipoprotein clearance is responsible for increased cholesterol in LDL receptor knockout mice with streptozotocin-induced diabetes

27 September 2018

1 reference

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Diabetes alters LDL receptor and PCSK9 expression in rat liver

27 September 2018

1 reference

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Atherogenic remnant lipoproteins: role for proteoglycans in trapping, transferring, and internalizing

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

The cis-9,trans-11 isomer of conjugated linoleic acid (CLA) lowers plasma triglyceride and raises HDL cholesterol concentrations but does not suppress aortic atherosclerosis in diabetic apoE-deficient mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

Proinsulin lacking the A7-B7 disulfide bond, Ins2Akita, tends to aggregate due to the exposed hydrophobic surface.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

Reduced intrahepatic fat content is associated with increased whole-body lipid oxidation in patients with type 1 diabetes

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

Rosiglitazone attenuates atherosclerosis in a model of insulin insufficiency independent of its metabolic effects

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

The Ins2Akita mouse as a model of early retinal complications in diabetes

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

Longitudinal evaluation of memory performance and peripheral neuropathy in the Ins2C96Y Akita mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

Apolipoprotein C-III protein concentrations and gene polymorphisms in type 1 diabetes: associations with lipoprotein subclasses.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

Hepatic catabolism of remnant lipoproteins: where the action is.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

Non-obese diabetic (NOD) mice exhibit an increased cellular immune response to glycated-LDL but are resistant to high fat diet induced atherosclerosis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

Serum leptin levels in type 1 diabetic and obese children: relation to insulin levels.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

Marked and rapid decreases of circulating leptin in streptozotocin diabetic rats: reversal by insulin

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

Overexpression of human apolipoprotein C-III in transgenic mice results in an accumulation of apolipoprotein B48 remnants that is corrected by excess apolipoprotein E.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129838

A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice

27 September 2018

1 reference

12 December 2020

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree

1 reference

12 December 2020

Accelerated atherosclerosis and premature calcified cartilaginous metaplasia in the aorta of diabetic male Apo E knockout mice can be prevented by chronic treatment with 17 beta-estradiol

1 reference

12 December 2020

Streptozotocin-induced diabetes in human apolipoprotein B transgenic mice. Effects on lipoproteins and atherosclerosis

1 reference

12 December 2020

High risk of cardiovascular disease in patients with type 1 diabetes in the U.K.: a cohort study using the general practice research database

1 reference

12 December 2020

10.1152/AJPENDO.00034.2011

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference