(Q35090220)

6 August 2017

title

Modulation of dendritic spines and synaptic function by Rac1: a possible link to Fragile X syndrome pathology (English)

1 reference

6 August 2017

1 reference

1 reference

Odelia Y N Bongmba

1

1 reference

6 August 2017

Luis A Martinez

2

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6 August 2017

Mary E Elhardt

3

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6 August 2017

Karlis Butler

4

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6 August 2017

Maria V Tejada-Simon

5

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6 August 2017

language of work or name

English

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publication date

17 May 2011

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6 August 2017

number of pages

17

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inferred from page(s)

published in

Brain Research

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6 August 2017

volume

1399

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6 August 2017

page(s)

79-95

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Pharmacological inactivation of the small GTPase Rac1 impairs long-term plasticity in the mouse hippocampus

6 August 2017

cites work

1 reference

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Myosin IIb regulates actin dynamics during synaptic plasticity and memory formation

8 July 2018

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Physiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome

8 July 2018

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PED interacts with Rac1 and regulates cell migration/invasion processes in human non-small cell lung cancer cells.

8 July 2018

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Critical period plasticity is disrupted in the barrel cortex of FMR1 knockout mice.

8 July 2018

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Different Rho GTPase-dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation

8 July 2018

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A central role for the small GTPase Rac1 in hippocampal plasticity and spatial learning and memory

8 July 2018

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Alpha-tocopherol protects against oxidative stress in the fragile X knockout mouse: an experimental therapeutic approach for the Fmr1 deficiency

8 July 2018

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Social behavior in Fmr1 knockout mice carrying a human FMR1 transgene

8 July 2018

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Enhancement of learning and memory after activation of cerebral Rho GTPases

8 July 2018

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LTP consolidation: substrates, explanatory power, and functional significance

8 July 2018

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Local protein synthesis and spine morphogenesis: Fragile X syndrome and beyond.

8 July 2018

1 reference

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NMDA receptor activation induces translocation and activation of Rac in mouse hippocampal area CA1

8 July 2018

1 reference

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Localization of FMRP-associated mRNA granules and requirement of microtubules for activity-dependent trafficking in hippocampal neurons

8 July 2018

1 reference

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FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts.

8 July 2018

1 reference

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Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses

8 July 2018

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Reactive oxygen species and synaptic plasticity in the aging hippocampus

8 July 2018

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Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

The fragile X syndrome: from molecular genetics to neurobiology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Hippocampal LTP is accompanied by enhanced F-actin content within the dendritic spine that is essential for late LTP maintenance in vivo

8 July 2018

1 reference

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Cdc42 & GSK-3: signals at the crossroads

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

New insights into fragile X syndrome: from molecules to neurobehaviors

8 July 2018

1 reference

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Activity-dependent regulation of dendritic growth and patterning

8 July 2018

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A decade of molecular studies of fragile X syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Altered synaptic plasticity in a mouse model of fragile X mental retardation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Monogenic causes of X-linked mental retardation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Morphological changes in dendritic spines associated with long-term synaptic plasticity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Synaptic regulation of protein synthesis and the fragile X protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Imaging high-resolution structure of GFP-expressing neurons in neocortex in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Dendritic spine structural anomalies in fragile-X mental retardation syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Small GTPases Rac and Rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Essential roles of Drosophila RhoA in the regulation of neuroblast proliferation and dendritic but not axonal morphogenesis

8 July 2018

1 reference

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The neuronal architecture of Xenopus retinal ganglion cells is sculpted by rho-family GTPases in vivo

8 July 2018

1 reference

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Dendritic spine changes associated with hippocampal long-term synaptic plasticity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Rapid Dendritic Morphogenesis in CA1 Hippocampal Dendrites Induced by Synaptic Activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Mapping of D1 dopamine receptor mRNA by non-radioactive in situ hybridization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Rho GTPases and signaling networks

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Subregion- and cell type-restricted gene knockout in mouse brain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Control of memory formation through regulated expression of a CaMKII transgene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Structural changes accompanying memory storage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Dendritic spines: cellular specializations imparting both stability and flexibility to synaptic function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Small GTP-binding proteins and the regulation of the actin cytoskeleton

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

A role for RhoB in synaptic plasticity and the regulation of neuronal morphology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Two boys with fragile x syndrome and hepatic tumors

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Enhanced markers of oxidative stress, altered antioxidants and NADPH-oxidase activation in brains from Fragile X mental retardation 1-deficient mice, a pathological model for Fragile X syndrome.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Translocation and activation of Rac in the hippocampus during associative contextual fear learning

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Brain-derived neurotrophic factor promotes long-term potentiation-related cytoskeletal changes in adult hippocampus.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Lost once, the Fragile X Mental Retardation protein is now back onto brain polyribosomes

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Fragile x syndrome associated with testicular microlithiasis in siblings.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Rac1 induces the clustering of AMPA receptors during spinogenesis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Theta stimulation polymerizes actin in dendritic spines of hippocampus.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Activation of Rho GTPases by synaptic transmission in the hippocampus

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Control of dendritic development by theDrosophila fragile X-relatedgene involves the small GTPase Rac1

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Reduced cortical synaptic plasticity and GluR1 expression associated with fragile X mental retardation protein deficiency.

27 September 2018

1 reference

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Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

FMRP involvement in formation of synapses among cultured hippocampal neurons.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

A role for the small molecular weight GTPases, Rho and Cdc42, in muscarinic receptor signaling to focal adhesion kinase

27 September 2018

1 reference

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(Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features

27 September 2018

1 reference

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Differential expression of peroxisome proliferator-activated receptor-alpha, -beta, and -gamma during rat embryonic development

27 September 2018

1 reference

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Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines.

27 September 2018

1 reference

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Nucleus basalis magnocellularis and hippocampus are the major sites of FMR-1 expression in the human fetal brain

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Dendritic Spine "Dysgenesis" and Mental Retardation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131096

Immunocytochemical and biochemical characterization of FMRP, FXR1P, and FXR2P in the mouse

27 September 2018

1 reference

12 December 2020

CaMKIIalpha-Cre transgene expression and recombination patterns in the mouse brain

1 reference

12 December 2020

Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo

1 reference

12 December 2020

Regulation of dendritic spine morphology by the rho family of small GTPases: antagonistic roles of Rac and Rho

1 reference

12 December 2020

Critical Roles for Rac1 and Rac2 GTPases in B Cell Development and Signaling

1 reference

12 December 2020

10.1016/J.BRAINRES.2011.05.020

Identifiers

DOI

1 reference

release_tke76rtw7zg57ij3tln5wz5lde

6 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tke76rtw7zg57ij3tln5wz5lde

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3131096

1 reference

6 August 2017

1 reference