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Signaling and transcriptional control of Fas ligand gene expression.
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Europe PubMed Central
PubMed publication ID
12655294
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655294%20AND%20SRC:MED&resulttype=core&format=json
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1 November 2019
title
Signaling and transcriptional control of Fas ligand gene expression
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655294
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655294%20AND%20SRC:MED&resulttype=core&format=json
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1 November 2019
author
Mary M Kavurma
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1
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Europe PubMed Central
PubMed publication ID
12655294
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655294%20AND%20SRC:MED&resulttype=core&format=json
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1 November 2019
Levon Khachigian
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2
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Europe PubMed Central
PubMed publication ID
12655294
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655294%20AND%20SRC:MED&resulttype=core&format=json
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1 November 2019
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Kavurma MM
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1
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Europe PubMed Central
PubMed publication ID
12655294
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6 August 2017
Khachigian LM
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2
1 reference
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Europe PubMed Central
PubMed publication ID
12655294
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6 August 2017
publication date
1 January 2003
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Europe PubMed Central
PubMed publication ID
12655294
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1 November 2019
published in
Cell Death & Differentiation
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Europe PubMed Central
PubMed publication ID
12655294
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655294%20AND%20SRC:MED&resulttype=core&format=json
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1 November 2019
volume
10
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Europe PubMed Central
PubMed publication ID
12655294
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655294%20AND%20SRC:MED&resulttype=core&format=json
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1 November 2019
issue
1
1 reference
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Europe PubMed Central
PubMed publication ID
12655294
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655294%20AND%20SRC:MED&resulttype=core&format=json
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1 November 2019
page(s)
36-44
1 reference
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Europe PubMed Central
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12655294
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655294%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401179
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Fas ligand-induced apoptosis
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The Fas counterattack: cancer as a site of immune privilege
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Fas ligand in human serum
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7 January 2021
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Expression of the functional soluble form of human fas ligand in activated lymphocytes.
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7 January 2021
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Separate domains of the human fas ligand dictate self-association and receptor binding
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Multiple interactions of the cytosolic polyproline region of the CD95 ligand: hints for the reverse signal transduction capacity of a death factor
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Biochemical pathways of caspase activation during apoptosis
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7 January 2021
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Caspases: the executioners of apoptosis
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Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L)
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Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)
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7 January 2021
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Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.
1 reference
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7 January 2021
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Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.
1 reference
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Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide
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7 January 2021
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Expression of Fas in B cells of the mouse germinal center and Fas-dependent killing of activated B cells
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CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells
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7 January 2021
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Requirement of Fas expression in B cells for tolerance induction
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7 January 2021
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Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.
1 reference
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Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.
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7 January 2021
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CD8+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity.
1 reference
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Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
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7 January 2021
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Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity
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Crossref
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7 January 2021
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gld/gld mice are unable to express a functional ligand for Fas.
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CD95 engagement induces disseminated endothelial cell apoptosis in vivo: immunopathologic implications.
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Apoptosis by death factor
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Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege
1 reference
stated in
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reference URL
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7 January 2021
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inferred from DOI database lookup
CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival
1 reference
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Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice
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7 January 2021
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A role for CD95 ligand in preventing graft rejection
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Resistance to Fas (APO-1/CD95)-mediated apoptosis and expression of Fas ligand in esophageal cancer: the Fas counterattack
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7 January 2021
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T cell-tumor cell: a fatal interaction?
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Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape
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Countering the 'counterattack' hypothesis.
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Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts.
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Not so Fas: Re-evaluating the mechanisms of immune privilege and tumor escape
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Apoptosis in human atherosclerosis and restenosis
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Crossref
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inferred from DOI database lookup
Inhibition of neointimal cell bcl-x expression induces apoptosis and regression of vascular disease.
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Fas is expressed in human atherosclerotic intima and promotes apoptosis of cytokine-primed human vascular smooth muscle cells
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fas ligand-deficient mice display enhanced leukocyte infiltration and intima hyperplasia in flow-restricted vessels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
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7 January 2021
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inferred from DOI database lookup
Molecular determinants of atherosclerotic plaque vulnerability
1 reference
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reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
Smooth muscle cell apoptosis in arteriosclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
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inferred from DOI database lookup
Human blood-derived macrophages induce apoptosis in human plaque-derived vascular smooth muscle cells by Fas-ligand/Fas interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased plasma levels of the soluble form of Fas ligand in patients with acute myocardial infarction and unstable angina pectoris
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas ligand, death gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transmission between the plasma membrane and nucleus of T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of NF-AT in type I human T-cell leukemia virus Tax-mediated Fas ligand promoter transactivation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NFkappaB-dependent signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear factor kappa B: important transcription factor and therapeutic target
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappaB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sp1 phosphorylation regulates apoptosis via extracellular FasL-Fas engagement
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ets-1 positively regulates Fas ligand transcription via cooperative interactions with Sp1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FasL promoter activation by IL-2 through SP1 and NFAT but not Egr-2 and Egr-3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclosporin A-sensitive transcription factor Egr-3 regulates Fas ligand expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pathways of Egr-1-mediated gene transcription in vascular biology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel Egr/NF-AT composite sites mediate activation of the CD95 (APO-1/Fas) ligand promoter in response to T cell stimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of Egr-2 in up-regulation of Fas ligand in normal T cells and aberrant double-negative lpr and gld T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequential involvement of NFAT and Egr transcription factors in FasL regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV Tat binds Egr proteins and enhances Egr-dependent transactivation of the Fas ligand promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The IFN regulatory factor family participates in regulation of Fas ligand gene expression in T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Viral IFN-regulatory factors inhibit activation-induced cell death via two positive regulatory IFN-regulatory factor 1-dependent domains in the CD95 ligand promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis in fibroblasts by c-myc protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional Myc-Max heterodimer is required for activation-induced apoptosis in T cell hybridomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of Fas ligand in activated T cells is regulated by c-Myc
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A 'non-canonical' DNA-binding element mediates the response of the Fas-ligand promoter to c-Myc.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor beta1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-2 receptor common gamma-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: selective induction of anti-apoptotic (bcl-2, bcl-xL) but not pro-apoptotic (bax, bcl-xS) gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-2 reverses the defect in activation-induced apoptosis in T cells from autoimmune lpr mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-2 deficient mice: a new model to study autoimmunity and self-tolerance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of interleukin-2 in regulating the sensitivity of natural killer cells for Fas-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transforming growth factor-beta family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta induces the expression of the FLICE-inhibitory protein and inhibits Fas-mediated apoptosis of microglia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta is required for programmed cell death in interdigital webs of the developing mouse limb
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Repression of FasL expression by retinoic acid involves a novel mechanism of inhibition of transactivation function of the nuclear factors of activated T-cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficient Inhibition of Activation-induced Fas Ligand Up-regulation and T Cell Apoptosis by Retinoids Requires Occupancy of both Retinoid X Receptors and Retinoic Acid Receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of CD95 ligand gene expression by vitamin D3 in T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential inducibility of the transcriptional repressor ICER and its role in modulation of Fas ligand expression in T and NK lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401179
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4401179
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655294
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655294%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
PubMed publication ID
12655294
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12655294
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655294%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
ResearchGate publication ID
10840381
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