(Q45971909)

18 December 2017

title

CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells. (English)

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18 December 2017

author name string

Rathmell JC

1

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18 December 2017

Cooke MP

2

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18 December 2017

Ho WY

3

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18 December 2017

Grein J

4

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18 December 2017

Townsend SE

5

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18 December 2017

Davis MM

6

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18 December 2017

Goodnow CC

7

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18 December 2017

language of work or name

English

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publication date

1 July 1995

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18 December 2017

published in

Nature

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18 December 2017

volume

376

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18 December 2017

page(s)

181-184

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18 December 2017

issue

6536

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18 December 2017

https://scigraph.springernature.com/pub.10.1038/376181a0

exact match

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cites work

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1 reference

7 January 2021

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

1 reference

7 January 2021

The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster.

1 reference

7 January 2021

Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease

1 reference

7 January 2021

An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity.

1 reference

7 January 2021

Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice

1 reference

7 January 2021

Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells.

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7 January 2021

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

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7 January 2021

Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells.

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7 January 2021

Anergic B cells constitutively present self antigen: Enhanced immunoglobulin receptor-mediated presentation of antigenic determinants by B cells is hierarchical

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7 January 2021

A new allele of the lpr locus, lprcg, that complements the gld gene in induction of lymphadenopathy in the mouse

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7 January 2021

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

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7 January 2021

Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens.

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7 January 2021

Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.

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7 January 2021

Monoclonal antibody-mediated tumor regression by induction of apoptosis.

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7 January 2021

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7 January 2021

Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells.

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7 January 2021

Self-tolerance checkpoints in B lymphocyte development.

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7 January 2021

Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice

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7 January 2021

Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide

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7 January 2021

A specific intercellular pathway of apoptotic cell death is defective in the mature peripheral T cells of autoimmune lpr and gld mice

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7 January 2021

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

1 reference

7 January 2021

Reduced life span of anergic self-reactive B cells in a double-transgenic model.

1 reference

7 January 2021

Identifiers

DOI

10.1038/376181A0

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18 December 2017

Dimensions Publication ID

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18 December 2017