(Q35091596)

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Increased abundance of the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1) in patients with obesity and type 2 diabetes: evidence for altered adiponectin signalling

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 August 2017

Increased abundance of the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1) in patients with obesity and type 2 diabetes: evidence for altered adiponectin signalling (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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type 2 diabetes

1 reference

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inferred from title

Lawrence J Mandarino

14

object named as

L J Mandarino

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Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

R M Holmes

1

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Europe PubMed Central

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6 August 2017

Z Yi

2

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6 August 2017

E De Filippis

3

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6 August 2017

R Berria

4

1 reference

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6 August 2017

S Shahani

5

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6 August 2017

P Sathyanarayana

6

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6 August 2017

V Sherman

7

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6 August 2017

K Fujiwara

8

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6 August 2017

C Meyer

9

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Europe PubMed Central

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6 August 2017

C Christ-Roberts

10

1 reference

Europe PubMed Central

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6 August 2017

H Hwang

11

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6 August 2017

J Finlayson

12

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6 August 2017

L Q Dong

13

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6 August 2017

M Bajaj

15

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6 August 2017

publication date

12 May 2011

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6 August 2017

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6 August 2017

54

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6 August 2017

8

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6 August 2017

2122-2131

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Europe PubMed Central

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6 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3131511/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Label-free relative quantification of co-eluting isobaric phosphopeptides of insulin receptor substrate-1 by HPLC-ESI-MS/MS.

1 reference

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APPL1 associates with TrkA and GIPC1 and is required for nerve growth factor-mediated signal transduction

1 reference

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APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function

1 reference

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Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity

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Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes

1 reference

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Human follicle-stimulating hormone (FSH) receptor interacts with the adaptor protein APPL1 in HEK 293 cells: potential involvement of the PI3K pathway in FSH signaling

1 reference

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Protein measurement with the Folin phenol reagent

1 reference

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Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

1 reference

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APPL suppresses androgen receptor transactivation via potentiating Akt activity

1 reference

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Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation

1 reference

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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

1 reference

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Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women

1 reference

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Mediation of the DCC apoptotic signal by DIP13 alpha

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

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8 July 2018

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

1 reference

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8 July 2018

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

1 reference

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8 July 2018

Decreased expression of apM1 in omental and subcutaneous adipose tissue of humans with type 2 diabetes

1 reference

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8 July 2018

Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia

1 reference

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Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

1 reference

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Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway

1 reference

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Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages

1 reference

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Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2

1 reference

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Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

1 reference

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Increased collagen content in insulin-resistant skeletal muscle

1 reference

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Impaired activation of AMP-kinase and fatty acid oxidation by globular adiponectin in cultured human skeletal muscle of obese type 2 diabetics

1 reference

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AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females

1 reference

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Expression of key genes of fatty acid oxidation, including adiponectin receptors, in skeletal muscle of Type 2 diabetic patients

1 reference

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5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes

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1 reference

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Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.

1 reference

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1 reference

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21 January 2018

Identifiers

10.1007/S00125-011-2173-X

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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