(Q35094206)

6 August 2017

8 references

31 July 2019

20 August 2019

19 September 2019

18 November 2019

15 December 2019

4 September 2020

10 September 2020

19 July 2022

TGR5: a novel target for weight maintenance and glucose metabolism (English)

1 reference

6 August 2017

main subject

cell surface receptor

1 reference

31 July 2019

physiological phenomenon

1 reference

biomedical investigative technique

20 August 2019

1 reference

19 September 2019

1 reference

18 November 2019

1 reference

15 December 2019

1 reference

4 September 2020

G protein-coupled receptor

1 reference

10 September 2020

Xiaosong Chen

1

1 reference

6 August 2017

Guiyu Lou

series ordinal

2

1 reference

6 August 2017

Zhipeng Meng

series ordinal

3

1 reference

6 August 2017

Wendong Huang

series ordinal

4

1 reference

6 August 2017

publication date

21 June 2011

9 references

Experimental Diabetes Research

6 August 2017

31 July 2019

20 August 2019

19 September 2019

18 November 2019

15 December 2019

4 September 2020

10 September 2020

19 July 2022

9 references

6 August 2017

31 July 2019

20 August 2019

19 September 2019

18 November 2019

15 December 2019

4 September 2020

10 September 2020

19 July 2022

2011

1 reference

6 August 2017

page(s)

853501

1 reference

Creative Commons Attribution 3.0 Unported

6 August 2017

copyright license

8 references

31 July 2019

20 August 2019

19 September 2019

18 November 2019

15 December 2019

4 September 2020

10 September 2020

Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis

19 July 2022

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Functional characterization of the semisynthetic bile acid derivative INT-767, a dual farnesoid X receptor and TGR5 agonist.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Bile acid-activated receptors in the treatment of dyslipidemia and related disorders

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

TGR5-mediated bile acid sensing controls glucose homeostasis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Functional brown adipose tissue in healthy adults

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Identification and importance of brown adipose tissue in adult humans

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Cold-activated brown adipose tissue in healthy men

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Farnesoid X receptor agonists in biliary tract disease

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

FXR: a metabolic regulator and cell protector

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

PRDM16 controls a brown fat/skeletal muscle switch

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Expression and function of the bile acid receptor TGR5 in Kupffer cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Transcriptional control of brown fat determination by PRDM16

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

International Union of Pharmacology. LXII. The NR1H and NR1I receptors: constitutive androstane receptor, pregnene X receptor, farnesoid X receptor alpha, farnesoid X receptor beta, liver X receptor alpha, liver X receptor beta, and vitamin D recept

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Cholestatic liver disease. Recognizing the clinical signs

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

FXR, a multipurpose nuclear receptor

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Epidemiology, trends, and morbidities of obesity and the metabolic syndrome

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

LXRS and FXR: the yin and yang of cholesterol and fat metabolism

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

International Union of Pharmacology. XLVI. G protein-coupled receptor list.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Bile acids as carcinogens in human gastrointestinal cancers

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Brown adipose tissue: function and physiological significance

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

The enzymes, regulation, and genetics of bile acid synthesis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

A G protein-coupled receptor responsive to bile acids

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Identification of membrane-type receptor for bile acids (M-BAR)

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Bile acids are physiological ligands for a nuclear receptor.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Bile acids: natural ligands for an orphan nuclear receptor

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Identification of a nuclear receptor for bile acids

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Identification of a nuclear receptor that is activated by farnesol metabolites

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Immediate neuroendocrine signaling after partial hepatectomy through acute portal hyperpressure and cholestasis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Beneficial actions of oleanolic acid in an experimental model of multiple sclerosis: a potential therapeutic role

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Hypermetabolism of fat in V1a vasopressin receptor knockout mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132465

Chronic fibrosing cholangiopathies: a consequence of a defective HCO₃⁻ "umbrella"?

27 September 2018

1 reference

12 December 2020

Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea

1 reference

12 December 2020

Synthesis and structure-activity relationships of a series of 3-aryl-4-isoxazolecarboxamides as a new class of TGR5 agonists

1 reference

12 December 2020

Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration

1 reference

12 December 2020

The membrane-bound bile acid receptor TGR5 (Gpbar-1) is localized in the primary cilium of cholangiocytes

1 reference

12 December 2020

Identifiers

DOI

10.1155/2011/853501

1 reference

6 August 2017

1 reference

6 August 2017

1 reference