(Q35095565)

6 August 2017

title

Complement receptor 2-mediated targeting of complement inhibitors to sites of complement activation (English)

1 reference

6 August 2017

Joel M Guthridge

4

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V Michael Holers

5

object named as

V Michael Holers

1 reference

6 August 2017

Hongbin Song

1

1 reference

6 August 2017

Chun He

2

1 reference

6 August 2017

Christian Knaak

3

1 reference

6 August 2017

Stephen Tomlinson

6

1 reference

6 August 2017

language of work or name

English

0 references

publication date

1 June 2003

1 reference

Journal of Clinical Investigation

6 August 2017

published in

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6 August 2017

volume

111

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6 August 2017

issue

12

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6 August 2017

page(s)

1875-1885

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6 August 2017

cites work

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Membrane-targeted complement inhibitors

9 July 2018

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Folded-back solution structure of monomeric factor H of human complement by synchrotron X-ray and neutron scattering, analytical ultracentrifugation and constrained molecular modelling

9 July 2018

1 reference

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Structure of complement receptor 2 in complex with its C3d ligand

9 July 2018

1 reference

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Structural studies in solution of the recombinant N-terminal pair of short consensus/complement repeat domains of complement receptor type 2 (CR2/CD21) and interactions with its ligand C3dg

9 July 2018

1 reference

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Regulation of the adhesion versus cytotoxic functions of the Mac-1/CR3/alphaMbeta2-integrin glycoprotein

9 July 2018

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Human and rodent decay-accelerating factors (CD55) are not species restricted in their complement-inhibiting activities

9 July 2018

1 reference

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The role of complement in B cell activation and tolerance.

9 July 2018

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Endothelial targeting and enhanced antiinflammatory effects of complement inhibitors possessing sialyl Lewisx moieties.

9 July 2018

1 reference

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Recombinant glycoproteins that inhibit complement activation and also bind the selectin adhesion molecules

9 July 2018

1 reference

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Protection of human breast cancer cells from complement-mediated lysis by expression of heterologous CD59.

9 July 2018

1 reference

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Targeting of functional antibody-CD59 fusion proteins to a cell surface

9 July 2018

1 reference

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Amelioration of lupus-like autoimmune disease in NZB/WF1 mice after treatment with a blocking monoclonal antibody specific for complement component C5.

9 July 2018

1 reference

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Structural composition and functional characterization of soluble CD59: heterogeneity of the oligosaccharide and glycophosphoinositol (GPI) anchor revealed by laser-desorption mass spectrometric analysis

9 July 2018

1 reference

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A functional analysis of recombinant soluble CD46 in vivo and a comparison with recombinant soluble forms of CD55 and CD35 in vitro

9 July 2018

1 reference

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A novel bifunctional chimeric complement inhibitor that regulates C3 convertase and formation of the membrane attack complex

9 July 2018

1 reference

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Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Renal localization of the membrane attack complex in systemic lupus erythematosus nephritis

9 July 2018

1 reference

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Cytolysis of nucleated cells by complement: cell death displays multi-hit characteristics

9 July 2018

1 reference

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Transmembrane channel formation by complement: functional analysis of the number of C5b6, C7, C8, and C9 molecules required for a single channel

9 July 2018

1 reference

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Number of hits necessary for complement-mediated hemolysis.

9 July 2018

1 reference

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The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester

9 July 2018

1 reference

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Structural and functional relationships among receptors and regulators of the complement system

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Mapping of the Epstein-Barr virus and C3dg binding sites to a common domain on complement receptor type 2.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Distribution of decay-accelerating factor in the peripheral blood of normal individuals and patients with paroxysmal nocturnal hemoglobinuria

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Biodistribution and radiation dose estimates for yttrium- and iodine-labeled monoclonal antibody IgG and fragments in nude mice bearing human colonic tumor xenografts

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Selective Enhancement of Leu-Cam Expression by Interleukin 6 during Differentiation of Human Promonocytic U937 Cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Mapping of epitopes, glycosylation sites, and complement regulatory domains in human decay accelerating factor

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Human recombinant soluble decay accelerating factor inhibits complement activation in vitro and in vivo

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Macrophage cytoskeleton association with CR3 and CR4 regulates receptor mobility and phagocytosis of iC3b-opsonized erythrocytes

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Action of the C3b-inactivator on the cell-bound C3b

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Kinetic analysis of the interactions of complement receptor 2 (CR2, CD21) with its ligands C3d, iC3b, and the EBV glycoprotein gp350/220.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Targeting of functional antibody-decay-accelerating factor fusion proteins to a cell surface

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Neuronal protection in stroke by an sLex-glycosylated complement inhibitory protein

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

The role of complement and complement receptors in induction and regulation of immunity.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Recombinant soluble CD59 inhibits reactive haemolysis with complement.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161422

Complement inhibition attenuates human lung transplant reperfusion injury: a multicenter trial

27 September 2018

1 reference

12 December 2020

Production and functional analysis of rat CD59 and chimeric CD59-Crry as active soluble proteins in Pichia pastoris

1 reference

12 December 2020

Production and functional characterization of a soluble recombinant form of mouse CD59

1 reference

12 December 2020

A recombinant soluble chimeric complement inhibitor composed of human CD46 and CD55 reduces acute cardiac tissue injury in models of pig-to-human heart transplantation

1 reference

12 December 2020

Therapeutic efficacy of a novel membrane-targeted complement regulator in antigen-induced arthritis in the rat

1 reference

12 December 2020

Characterization of three monoclonal antibodies against C3 with selective specificities

1 reference

12 December 2020

1 reference

12 December 2020

Soluble human complement receptor type 1: in vivo inhibitor of complement suppressing post-ischemic myocardial inflammation and necrosis

1 reference

12 December 2020

Epitope Mapping Using the X-Ray Crystallographic Structure of Complement Receptor Type 2 (CR2)/CD21: Identification of a Highly Inhibitory Monoclonal Antibody That Directly Recognizes the CR2-C3d Interface

1 reference

12 December 2020

A soluble chimeric inhibitor of C3 and C5 convertases, complement activation blocker-2, prolongs graft survival in pig-to-rhesus monkey heart transplantation

1 reference

12 December 2020

Rapid blood clearance of immunoglobulin G2a and immunoglobulin G2b in nude mice

1 reference

12 December 2020

Suppression of the Immune Response by a Soluble Complement Receptor of B Lymphocytes

1 reference

12 December 2020

A soluble chimeric complement inhibitory protein that possesses both decay-accelerating and factor I cofactor activities

1 reference

12 December 2020

Mapping the regions of the complement inhibitor CD59 responsible for its species selective activity

1 reference

12 December 2020

Blockade of antibody-induced glomerulonephritis with Crry-Ig, a soluble murine complement inhibitor

1 reference

12 December 2020

Limited proteolysis of complement protein C3b by regulatory enzyme C3b inactivator: isolation and characterization of a biologically active fragment, C3d,g

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI17348

1 reference

6 August 2017

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6 August 2017

1 reference