(Q35097231)

6 August 2017

title

A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases (English)

1 reference

6 August 2017

Stefan Kubicek

3

0 references

Stuart Schreiber

11

object named as

Stuart L Schreiber

1 reference

6 August 2017

10

Udo Oppermann

1 reference

6 August 2017

4

Johanna Myllyharju

1 reference

6 August 2017

Xuelai Luo

1

1 reference

6 August 2017

Yongxiang Liu

2

1 reference

6 August 2017

Anthony Tumber

5

1 reference

6 August 2017

Stanley Ng

6

1 reference

6 August 2017

Ka Hing Che

7

1 reference

6 August 2017

Jessica Podoll

8

1 reference

6 August 2017

Tom D Heightman

9

1 reference

6 August 2017

Xiang Wang

12

1 reference

6 August 2017

language of work or name

English

0 references

publication date

31 May 2011

1 reference

Journal of the American Chemical Society

6 August 2017

published in

1 reference

6 August 2017

volume

133

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6 August 2017

issue

24

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6 August 2017

page(s)

9451-9456

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Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors

6 August 2017

cites work

1 reference

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Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase

9 July 2018

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Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors.

9 July 2018

1 reference

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PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression

9 July 2018

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Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development

9 July 2018

1 reference

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Small-molecule-based inhibition of histone demethylation in cells assessed by quantitative mass spectrometry

9 July 2018

1 reference

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Development of homogeneous luminescence assays for histone demethylase catalysis and binding.

9 July 2018

1 reference

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UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis

9 July 2018

1 reference

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Chemical phylogenetics of histone deacetylases

9 July 2018

1 reference

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Regulation of alternative splicing by histone modifications

9 July 2018

1 reference

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Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic Approaches

9 July 2018

1 reference

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Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

9 July 2018

1 reference

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Identification of cell-active lysine specific demethylase 1-selective inhibitors

9 July 2018

1 reference

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A non-heme iron-mediated chemical demethylation in DNA and RNA

9 July 2018

1 reference

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The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors

9 July 2018

1 reference

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The future therapeutic potential of histone demethylases: A critical analysis.

9 July 2018

1 reference

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KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints

9 July 2018

1 reference

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Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Chemical probes for histone-modifying enzymes

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Histone modifying enzymes: structures, mechanisms, and specificities

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Mechanisms involved in the regulation of histone lysine demethylases

9 July 2018

1 reference

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Expanding chemical biology of 2-oxoglutarate oxygenases

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Histone lysine demethylases: emerging roles in development, physiology and disease

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

A histone H3 lysine 27 demethylase regulates animal posterior development

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Regulation of histone methylation by demethylimination and demethylation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Structural insights into histone demethylation by JMJD2 family members.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

A mechanism-based inactivator for histone demethylase LSD1.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Histone demethylation by a family of JmjC domain-containing proteins

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lung

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133600

An Improved Synthesis of O-Benzoyl Protected Hydroxamates

9 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21585201

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JA201597B

1 reference

release_gynbn334tjdnhglcwftjpcu5dq

6 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gynbn334tjdnhglcwftjpcu5dq

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

3133600

1 reference

6 August 2017

1 reference