(Q35104265)

6 August 2017

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title

Molecular abnormalities and correlations with tumor response and outcome in glioma patients (English)

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6 August 2017

Ian F Pollack

1

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6 August 2017

Ronald L Hamilton

series ordinal

2

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6 August 2017

Sydney D Finkelstein

series ordinal

3

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6 August 2017

Frank Lieberman

series ordinal

4

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6 August 2017

publication date

1 November 2002

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Neuroimaging clinics of North America

6 August 2017

published in

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6 August 2017

volume

12

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6 August 2017

issue

4

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6 August 2017

page(s)

627-639

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Progression as exemplified by human astrocytic tumors

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

A molecular genetic model of astrocytoma histopathology

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Chromosomal abnormalities in 47 pediatric brain tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Chromosomal characteristics of childhood brain tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Molecular biology of pediatric gliomas

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Cytogenetic and loss of heterozygosity studies in ependymomas, pilocytic astrocytomas, and oligodendrogliomas

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Nonrandom chromosomal gains in pilocytic astrocytomas of childhood.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Are juvenile pilocytic astrocytomas benign tumors? A cytogenetic study in 24 cases

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https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Deletions on the long arm of chromosome 17 in pilocytic astrocytoma.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Clonal expansion of p53 mutant cells is associated with brain tumour progression

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Cells with TP53 mutations in low grade astrocytic tumors evolve clonally to malignancy and are an unfavorable prognostic factor.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

P53, cell cycle control and apoptosis: Implications for cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Cancer therapy meets p53

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https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Wild-type p53 binds to the TATA-binding protein and represses transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Regulation of p53 stability by Mdm2

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https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Incidence of p14ARF gene deletion in high-grade adult and pediatric astrocytomas.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Growth suppression by p16ink4 requires functional retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Mutational profile of the PTEN gene in primary human astrocytic tumors and cultivated xenografts.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Subsets of glioblastoma multiforme defined by molecular genetic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Platelet derived growth factor (PDGF) autocrine components in human tumor cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Coexpression of platelet-derived growth factor (PDGF) B chain and PDGF B-type receptor in human gliomas.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Coexpression of platelet-derived growth factor (PDGF) and PDGF-receptor genes by primary human astrocytomas may contribute to their development and maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Signal transduction by receptors with tyrosine kinase activity

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https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

EGFR gene amplification--rearrangement in human glioblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Structural alterations of the epidermal growth factor receptor gene in human gliomas

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Prognostic implications of p53 protein, epidermal growth factor receptor, and Ki-67 labelling in brain tumours

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Lack of prognostic relevance of alterations in the epidermal growth factor receptor-transforming growth factor-alpha pathway in human astrocytic gliomas.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Pathways leading to glioblastoma multiforme: a molecular analysis of genetic alterations in 65 astrocytic tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Preferential inactivation of the p53 tumor suppressor pathway and lack of EGFR amplification distinguish de novo high grade pediatric astrocytomas from de novo adult astrocytomas

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

UCN-01 selectively enhances mitomycin C cytotoxicity in p53 defective cells which is mediated through S and/or G(2) checkpoint abrogation

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Molecular genetic evidence for subtypes of oligoastrocytomas.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Allelic status of chromosome 1 in neoplasms of the nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Long survival and therapeutic responses in patients with histologically disparate high-grade gliomas demonstrating chromosome 1p loss.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

High-grade astrocytomas in children: radiologically complete resection is associated with an excellent long-term prognosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Randomized phase III trial in childhood high-grade astrocytoma comparing vincristine, lomustine, and prednisone with the eight-drugs-in-1-day regimen. Childrens Cancer Group.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

The effectiveness of chemotherapy for treatment of high grade astrocytoma in children: results of a randomized trial. A report from the Childrens Cancer Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

The lack of a role for p53 in astrocytomas in pediatric patients

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Expression of p53 and prognosis in children with malignant gliomas.

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

Treatment of infants with malignant gliomas: the Pediatric Oncology Group experience

1 reference

https://api.crossref.org/works/10.1016%2FS1052-5149%2802%2900030-8

7 January 2021

10.1016/S1052-5149(02)00030-8

Identifiers

DOI

1 reference

6 August 2017

1 reference