(Q35104686)

6 August 2017

title

Synthesis and evaluation of multivalent branched HPMA copolymer-Fab' conjugates targeted to the B-cell antigen CD20. (English)

1 reference

6 August 2017

Russell N Johnson

1

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6 August 2017

Pavla Kopecková

series ordinal

2

1 reference

6 August 2017

Jindrich Kopecek

series ordinal

3

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6 August 2017

publication date

1 January 2009

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6 August 2017

published in

Bioconjugate Chemistry

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6 August 2017

volume

20

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6 August 2017

issue

1

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6 August 2017

page(s)

129-137

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Combination chemotherapy and photodynamic therapy with fab' fragment targeted HPMA copolymer conjugates in human ovarian carcinoma cells

6 August 2017

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9 July 2018

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9 July 2018

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9 July 2018

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Antiproliferative effect of a lectin- and anti-Thy-1.2 antibody-targeted HPMA copolymer-bound doxorubicin on primary and metastatic human colorectal carcinoma and on human colorectal carcinoma transfected with the mouse Thy-1.2 gene

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary struc

27 September 2018

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Negative cooperativity associated with binding of multivalent carbohydrates to lectins. Thermodynamic analysis of the "multivalency effect".

27 September 2018

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Homodimers but not monomers of Rituxan (chimeric anti-CD20) induce apoptosis in human B-lymphoma cells and synergize with a chemotherapeutic agent and an immunotoxin.

27 September 2018

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Efficacy of the chemotherapeutic action of HPMA copolymer-bound doxorubicin in a solid tumor model of ovarian carcinoma.

27 September 2018

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High-molecular weight HPMA copolymer-adriamycin conjugates

27 September 2018

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Effective inhibitors of hemagglutination by influenza virus synthesized from polymers having active ester groups. Insight into mechanism of inhibition

27 September 2018

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Binding of multivalent carbohydrates to concanavalin A and Dioclea grandiflora lectin. Thermodynamic analysis of the "multivalency effect"

27 September 2018

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12 December 2020

Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene

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12 December 2020

Binding to CD20 by anti-B1 antibody or F(ab')(2) is sufficient for induction of apoptosis in B-cell lines

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12 December 2020

Control of Multivalent Interactions by Binding Epitope Density

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12 December 2020

Influencing Receptor−Ligand Binding Mechanisms with Multivalent Ligand Architecture

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12 December 2020

Efficacy and safety of tositumomab and iodine-131 tositumomab (Bexxar) in B-cell lymphoma, progressive after rituximab

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12 December 2020

Polymer conjugates for drug targeting. From inspired to inspiration!

1 reference

12 December 2020

Expression of a supramolecular complex at a multivalent interface

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12 December 2020

EQUILIBRIUM THERMODYNAMICS AND BIOLOGICAL CHEMISTRY

1 reference

12 December 2020

Phosphorylation of the B1 (CD20) molecule by normal and malignant human B lymphocytes

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12 December 2020

Heterogeneity in the B1 (CD20) cell surface molecule expressed by human B-lymphocytes

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12 December 2020

Biocompatibility of N-(2-hydroxypropyl) methacrylamide copolymers containing adriamycin. Immunogenicity, and effect on haematopoietic stem cells in bone marrow in vivo and mouse splenocytes and human peripheral blood lymphocytes in vitro

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12 December 2020

Antibody-directed affinity therapy applied to the immune system: in vivo effectiveness and limited toxicity of daunomycin conjugated to HPMA copolymers and targeting antibody

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12 December 2020

Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors

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12 December 2020

Expression of human B cell-associated antigens on leukemias and lymphomas: a model of human B cell differentiation

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12 December 2020

A new strategy for attachment of antibodies to sterically stabilized liposomes resulting in efficient targeting to cancer cells

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12 December 2020

HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. 1. influence of the method of synthesis on the binding affinity to OVCAR-3 ovarian carcinoma cells in vitro

1 reference

12 December 2020

Amino acid analysis. Precolumn derivatization methods

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12 December 2020

Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies

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12 December 2020

Identifiers

DOI

10.1021/BC800351M

1 reference

6 August 2017

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6 August 2017

1 reference