(Q35104714)

English

Pharmacokinetic modeling of absorption behavior of 9-aminocamptothecin (9-AC) released from colon-specific HPMA copolymer-9-AC conjugate in rats

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Pharmacokinetic modeling of absorption behavior of 9-aminocamptothecin (9-AC) released from colon-specific HPMA copolymer-9-AC conjugate in rats (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Song-Qi Gao

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Yongen Sun

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Pavla Kopecková

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

C Matthew Peterson

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Jindrich Kopecek

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

11 October 2007

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

25

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

218-226

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Biodistribution and pharmacokinetics of colon-specific HPMA copolymer--9-aminocamptothecin conjugate in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Luminal delivery and dosing considerations of local celecoxib administration to colorectal cancer

1 reference

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9 July 2018

Drug targeting to the colon with lectins and neoglycoconjugates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Absorption of drugs from the stomach. I. The rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

The colon as a possible target for orally administered peptide and protein drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Analysis and prediction of absorption behavior of colon-targeted prodrug in rats by GI-transit-absorption model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Gastrointestinal transit and drug absorption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Relation between 9-aminocamptothecin systemic exposure and tumor response in human solid tumor xenografts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Approaches and opportunities in colon-specific drug delivery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Topoisomerase I inhibitors: the relevance of prolonged exposure for present clinical development

1 reference

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9 July 2018

Topoisomerase I and II activity in human breast, cervix, lung and colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Overview of drug-protein binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Stereoselective disposition of S-8666, a novel uricosuric antihypertensive diuretic, and its N-monodemethylated metabolite in a perfused rat liver preparation. Effect of protein binding on the kinetics of S-8666.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Hepatic clearance of drugs. II. Experimental evidence for acceptance of the “well-stirred” model over the “parallel tube” model using lidocaine in the perfused rat liverin situ preparation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Mechanism of the reaction catalyzed by the DNA untwisting enzyme: Attachment of the enzyme to 3′-terminus of the nicked DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Retention and degradation of 125I-insulin by perfused livers from diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

9 July 2018

Colon-specific 9-aminocamptothecin-HPMA copolymer conjugates containing a 1,6-elimination spacer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

27 September 2018

A study of the in vitro interaction between lidocaine and premedications using human liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

27 September 2018

Pharmacokinetic model-predicted anticancer drug concentrations in human tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

27 September 2018

Aggregation properties of a HPMA-camptothecin copolymer in isotonic solutions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

27 September 2018

The influence of a colonic microbiota on HPMA copolymer lectin conjugates binding in rodent intestine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

27 September 2018

Biorecognizable HPMA copolymer-drug conjugates for colon-specific delivery of 9-aminocamptothecin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

27 September 2018

Why drugs fail: of mice and men revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

27 September 2018

Analysis and prediction of absorption profile including hepatic first-pass metabolism of N-methyltyramine, a potent stimulant of gastrin release present in beer, after oral ingestion in rats by gastrointestinal-transit-absorption model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136142

27 September 2018

A polymeric drug for treatment of inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macromolecular prodrugs. XVI. Colon-targeted delivery--comparison of the rate of release of naproxen from dextran ester prodrugs in homogenates of various segments of the pig gastrointestinal (GI) tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The involvement of active DNA synthesis in camptothecin-induced G2 arrest: altered regulation of p34cdc2/cyclin B

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete inhibition of growth followed by death of human malignant melanoma cells in vitro and regression of human melanoma xenografts in immunodeficient mice induced by camptothecins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Camptothecin derivatives induce regression of human ovarian carcinomas grown in nude mice and distinguish between non-tumorigenic and tumorigenic cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological parameters in laboratory animals and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between replication forks and topoisomerase I-DNA cleavable complexes: studies in a cell-free SV40 DNA replication system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the active lactone form of 9-aminocamptothecin in plasma using solid-phase extraction and high-performance liquid chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An Optimized Model for Rat Liver Perfusion Studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential toxicity of camptothecin, topotecan and 9-aminocamptothecin to human, canine, and murine myeloid progenitors (CFU-GM) in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of the plasma concentration profiles of orally administered drugs in rats on the basis of gastrointestinal transit kinetics and absorbability

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I clinical and pharmacokinetic study of oral 9-aminocamptothecin (NSC-603071)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

12 December 2020

based on heuristic

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Biorecognition of HPMA copolymer-lectin conjugates as an indicator of differentiation of cell-surface glycoproteins in development, maturation, and diseases of human and rodent gastrointestinal tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

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based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of orally administered camptothecins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17929146

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based on heuristic

inferred from PubMed ID database lookup

Synthesis of bioadhesive lectin-HPMA copolymer-cyclosporin conjugates

1 reference

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1 reference

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A new approach to the oral administration of insulin and other peptide drugs

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https://pubmed.ncbi.nlm.nih.gov/17929146

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Identifiers

10.1007/S11095-007-9465-3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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