(Q35104715)

6 August 2017

1 reference

title

AMP-activated protein kinase (AMPK) control of fatty acid and glucose metabolism in the ischemic heart (English)

1 reference

6 August 2017

0 references

1 reference

https://api.crossref.org/works/10.1016/S0163-7827(02)00065-6

23 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0163-7827(02)00065-6

23 December 2023

author name string

Nandakumar Sambandam

1

1 reference

6 August 2017

Gary D. Lopaschuk

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12689619

23 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12689619

23 December 2023

publication date

1 May 2003

1 reference

full work available at URL

6 August 2017

https://api.elsevier.com/content/article/PII:S0163782702000656?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0163-7827(02)00065-6

https://api.elsevier.com/content/article/PII:S0163782702000656?httpAccept=text/plain

23 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0163-7827(02)00065-6

Progress in Lipid Research

23 December 2023

published in

1 reference

6 August 2017

volume

42

1 reference

6 August 2017

issue

3

1 reference

6 August 2017

page(s)

238-256

1 reference

Consequences of brief ischemia: stunning, preconditioning, and their clinical implications: part 1.

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Clinical trials update: The Heart Protection Study, IONA, CARISA, ENRICHD, ACUTE, ALIVE, MADIT II and REMATCH. Impact Of Nicorandil on Angina. Combination Assessment of Ranolazine In Stable Angina. ENhancing Recovery In Coronary Heart Disease patien

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Acute effects of heparin administration on the ischemic threshold of patients with coronary artery disease: evaluation of the protective role of the metabolic modulator trimetazidine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Ranolazine: a potential new treatment for chronic stable angina

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Metabolic approaches to the treatment of ischemic heart disease: the clinicians' perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

AMP-activated protein kinase: the energy charge hypothesis revisited

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5'-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Characterization of 5'AMP-activated protein kinase activity in the heart and its role in inhibiting acetyl-CoA carboxylase during reperfusion following ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Alterations in fatty acid oxidation during reperfusion of the heart after myocardial ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Effects of glucose and fatty acids on myocardial ischaemia and arrhythmias

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

High levels of fatty acids delay the recovery of intracellular pH and cardiac efficiency in post-ischemic hearts by inhibiting glucose oxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Sustained regional abnormalities in cardiac metabolism after transient ischemia in the chronic dog model

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Cardiac efficiency is improved after ischemia by altering both the source and fate of protons

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

In vitro phosphorylation of 3-hydroxy-3-methylglutaryl coenzyme a reductase: Analysis of 32P-labeled, inactivated enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

3-Hydroxy-3-methylglutaryl coenzyme A reductase: regulation of enzymatic activity by phosphorylation and dephosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Activation of rat liver cytosolic 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase by adenosine 5'-monophosphate.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Glucose regulates protein interactions within the yeast SNF1 protein kinase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Characterization and chromosomal localization of the human homologue of a rat AMP-activated protein kinase-encoding gene: a major regulator of lipid metabolism in mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Molecular cloning, expression and chromosomal localisation of human AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Post-translational modifications of the beta-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

An activating mutation in the gamma1 subunit of the AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Cardiomyopathies: from genetics to the prospect of treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Mutations in the gamma(2) subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Novel PRKAG2 mutation responsible for the genetic syndrome of ventricular preexcitation and conduction system disease with childhood onset and absence of cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

5'-AMP activates the AMP-activated protein kinase cascade, and Ca2+/calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

AMP-activated protein kinase kinase: detection with recombinant AMPK alpha1 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Expression and regulation of the AMP-activated protein kinase-SNF1 (sucrose non-fermenting 1) kinase complexes in yeast and mammalian cells: studies using chimaeric catalytic subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Regulation of cardiac AMP-specific 5'-nucleotidase during ischemia mediates ATP resynthesis on reflow

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

The relationship between AMP-activated protein kinase activity and AMP concentration in the isolated perfused rat heart

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Insulin antagonizes AMP-activated protein kinase activation by ischemia or anoxia in rat hearts, without affecting total adenine nucleotides.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Actions of insulin on the mammalian heart: metabolism, pathology and biochemical mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Identification and differentiation of resting myocardial ischemia and infarction in man with positron computed tomography, 18F-labeled fluorodeoxyglucose and N-13 ammonia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Glucose delivery is a major determinant of glucose utilisation in the ischemic myocardium with a residual coronary flow

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Metabolic stress and altered glucose transport: activation of AMP-activated protein kinase as a unifying coupling mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Increased adenosine monophosphate-activated protein kinase activity in rat hearts with pressure-overload hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Alteration of glycogen and glucose metabolism in ischaemic and post-ischaemic working rat hearts by adenosine A1 receptor stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Low-flow ischemia leads to translocation of canine heart GLUT-4 and GLUT-1 glucose transporters to the sarcolemma in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Dissociation of 5' AMP-activated protein kinase activation and glucose uptake stimulation by mitochondrial uncoupling and hyperosmolar stress: differential sensitivities to intracellular Ca2+ and protein kinase C inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Chronic activation of 5'-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

5'-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D-riboside (AICAR)-stimulated glucose transport

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Metabolism of free fatty acids, glucose and catecholamines in acute myocardial infarction. Relation to myocardial ischemia and infarct size

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Metabolic response of the heart in acute myocardial infarction in man

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Plasma fatty acid levels in infants and adults after myocardial ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Etomoxir, a carnitine palmitoyltransferase I inhibitor, protects hearts from fatty acid-induced ischemic injury independent of changes in long chain acylcarnitine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Regulation of fatty acid and cholesterol metabolism by the AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Role of reversible phosphorylation of acetyl-CoA carboxylase in long-chain fatty acid synthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Malonyl-CoA metabolism in cardiac myocytes and its relevance to the control of fatty acid oxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Phosphorylation control of cardiac acetyl-CoA carboxylase by cAMP-dependent protein kinase and 5'-AMP activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Evidence that acetyl-CoA carboxylase isoforms play different biological roles in H9c2 cardiomyocyte

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Multiple-site phosphorylation of the 280 kDa isoform of acetyl-CoA carboxylase in rat cardiac myocytes: evidence that cAMP-dependent protein kinase mediates effects of beta-adrenergic stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Insulin inhibition of 5' adenosine monophosphate-activated protein kinase in the heart results in activation of acetyl coenzyme A carboxylase and inhibition of fatty acid oxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Phosphorylation-activity relationships of AMPK and acetyl-CoA carboxylase in muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Upregulation of 5'-AMP-activated protein kinase is responsible for the increase in myocardial fatty acid oxidation rates following birth in the newborn rabbit

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Activation of Malonyl-CoA Decarboxylase in Rat Skeletal Muscle by Contraction and the AMP-activated Protein Kinase Activator 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Malonyl-CoA decarboxylase is not a substrate of AMP-activated protein kinase in rat fast-twitch skeletal muscle or an islet cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Role of AMP-activated protein kinase in mechanism of metformin action

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Effect of AICAR treatment on glycogen metabolism in skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Identification of a gene responsible for familial Wolff-Parkinson-White syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2802%2900065-6

7 January 2021

Acute myocardial ischemia causes a transmural gradient in glucose extraction but not glucose uptake

54

1 reference

https://api.crossref.org/works/10.1016/S0163-7827(02)00065-6

Effects of high levels of fatty acids on functional recovery of ischemic hearts from diabetic rats

23 December 2023

75

1 reference

https://api.crossref.org/works/10.1016/S0163-7827(02)00065-6

Contribution of malonyl-CoA decarboxylase to the high fatty acid oxidation rates seen in the diabetic heart

23 December 2023

76

1 reference

https://api.crossref.org/works/10.1016/S0163-7827(02)00065-6

23 December 2023

Identifiers

1 reference

6 August 2017

1 reference