(Q34623707)

3 August 2017

1 reference

title

Metabolic approaches to the treatment of ischemic heart disease: the clinicians' perspective (English)

1 reference

3 August 2017

1 reference

coronary artery disease

1 reference

Andrew A Wolff

1

1 reference

3 August 2017

Heschi H Rotmensch

series ordinal

2

1 reference

3 August 2017

William C Stanley

series ordinal

3

1 reference

3 August 2017

Roberto Ferrari

series ordinal

4

1 reference

3 August 2017

publication date

1 April 2002

1 reference

3 August 2017

published in

Heart Failure Reviews

1 reference

3 August 2017

volume

7

1 reference

3 August 2017

issue

2

1 reference

3 August 2017

page(s)

187-203

1 reference

https://scigraph.springernature.com/pub.10.1023/a:1015384710373

3 August 2017

exact match

0 references

cites work

L-propionylcarnitine increases postischemic blood flow but does not affect recovery of energy charge

1 reference

12 December 2020

A double-blind trial of perhexiline maleate in the prophylaxis of angina pectoris

1 reference

12 December 2020

Effect of nicotinic acid on myocardial metabolism in man at rest and during exercise

1 reference

12 December 2020

Comparative trial of perhexiline maleate and oxprenolol in patients with angina pectoris

1 reference

12 December 2020

Direct evidence that perhexiline modifies myocardial substrate utilization from fatty acids to lactate

1 reference

12 December 2020

Metabolic response of the heart in acute myocardial infarction in man

1 reference

12 December 2020

Patients with intractable angina: free thyroxine index, immunoreactive insulin and free fatty acids in blood, free adrenaline and noradrenaline in urine.

1 reference

12 December 2020

Myocardial infarction and left ventricular remodeling: results of the CEDIM trial. Carnitine Ecocardiografia Digitalizzata Infarto Miocardico

1 reference

12 December 2020

Trimetazidine. A review of its use in stable angina pectoris and other coronary conditions

1 reference

12 December 2020

Anti-ischaemic efficacy and tolerability of trimetazidine administered to patients with angina pectoris: results of three studies

1 reference

12 December 2020

Three-year survival of patients with heart failure caused by dilated cardiomyopathy and L-carnitine administration

1 reference

12 December 2020

Dichloroacetate stimulation of glucose oxidation improves recovery of ischemic rat hearts

1 reference

12 December 2020

Polymorphism of carbon oxidation of drugs and clinical implications

1 reference

12 December 2020

Anti-ischemic effects of trimetazidine: 31P-NMR spectroscopy in the isolated rat heart

1 reference

12 December 2020

Serum Cortisol, Plasma Free Fatty Acids, and Urinary Catecholamines as Indicators of Complications in Acute Myocardial Infarction

1 reference

12 December 2020

Limitation of myocardial infarct size by metabolic interventions that reduce accumulation of fatty acid metabolites in ischemic myocardium

1 reference

12 December 2020

Beneficial effect of carnitine on mechanical recovery of rat hearts reperfused after a transient period of global ischemia is accompanied by a stimulation of glucose oxidation

1 reference

12 December 2020

Effects of L-propionylcarnitine on ischemia-induced myocardial dysfunction in men with angina pectoris.

1 reference

12 December 2020

Efficacy and safety of perhexiline maleate in refractory angina. A double-blind placebo-controlled clinical trial of a novel antianginal agent

1 reference

12 December 2020

Glucose-insulin-potassium therapy for treatment of acute myocardial infarction: an overview of randomized placebo-controlled trials

1 reference

12 December 2020

Proceedings: The absorption, excretion and metabolism of perhexiline maleate by the human

1 reference

12 December 2020

Uncoupling of contractile function from mitochondrial TCA cycle activity and MVO2 during reperfusion of ischemic hearts

1 reference

12 December 2020

Abnormal mechanical function in diabetes: relationship to altered myocardial carbohydrate/lipid metabolism

1 reference

12 December 2020

Relation between serum-free-fatty acids and arrhythmias and death after acute myocardial infarction

1 reference

12 December 2020

Comparison of negative inotropic potency, reversibility, and effects on calcium influx of six calcium channel antagonists in cultured myocardial cells

1 reference

12 December 2020

The pharmacology of dichloroacetate

1 reference

12 December 2020

Influence of coronary-effective substances on the concentration of nonesterified fatty acids in the serum of patients with angina pectoris

1 reference

12 December 2020

An in vitro method for the evaluation of antiarrhythmic and antiischemic agents by using programmed electrical stimulation of rabbit heart.

1 reference

12 December 2020

Trimetazidine: a new concept in the treatment of angina. Comparison with propranolol in patients with stable angina. Trimetazidine European Multicenter Study Group

1 reference

12 December 2020

Upregulation of 5'-AMP-activated protein kinase is responsible for the increase in myocardial fatty acid oxidation rates following birth in the newborn rabbit

1 reference

12 December 2020

Free fatty acids, beta-hydroxybutyrate, and ischaemic heart-disease.

1 reference

12 December 2020

Cellular uncoupling induced by accumulation of long-chain acylcarnitine during ischemia

1 reference

12 December 2020

Transport and function of L-carnitine and L-propionylcarnitine: relevance to some cardiomyopathies and cardiac ischemia

1 reference

12 December 2020

Effect of a nicotinic-acid analogue on raised plasma-free-fatty-acids after acute myocardial infarction.

1 reference

12 December 2020

Protective effects of ranolazine in guinea-pig hearts during low-flow ischaemia and their association with increases in active pyruvate dehydrogenase

1 reference

12 December 2020

Myocardial Lipid and Carbohydrate Metabolism in Healthy, Fasting Men at Rest: Studies During Continuous Infusion of 3H‐Palmitate

1 reference

12 December 2020

Effects of pacing-induced ischemia on myocardial free fatty acid extractions

1 reference

12 December 2020

Myocardial turnover of plasma free fatty acids during angina pectoris induced by atrial pacing

1 reference

12 December 2020

Impaired oxidation of debrisoquine in patients with perhexiline neuropathy

1 reference

12 December 2020

Assessment of anti-ischemic and antianginal effect at trough plasma concentration and safety of trimetazidine MR 35 mg in patients with stable angina pectoris: a multicenter, double-blind, placebo-controlled study

1 reference

12 December 2020

Ranolazine stimulates glucose oxidation in normoxic, ischemic, and reperfused ischemic rat hearts

1 reference

12 December 2020

Early detection of myocardial ischemia by myocardial free fatty acid extraction in patients with exercise-induced angina pectoris

1 reference

12 December 2020

Changes in intracellular sodium and pH during ischaemia-reperfusion are attenuated by trimetazidine. Comparison between low- and zero-flow ischaemia

1 reference

12 December 2020

Propionyl L-carnitine improvement of hypertrophied heart function is accompanied by an increase in carbohydrate oxidation

1 reference

12 December 2020

Trauma metabolism and the heart. Uptake of substrates and effects of insulin early after cardiac operations.

1 reference

12 December 2020

Superiority of L-propionylcarnitine vs L-carnitine in improving walking capacity in patients with peripheral vascular disease: an acute, intravenous, double-blind, cross-over study

1 reference

12 December 2020

Effects of excess free fatty acids on mechanical and metabolic function in normal and ischemic myocardium in swine

1 reference

12 December 2020

The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase

1 reference

12 December 2020

Propionyl-L-carnitine-mediated improvement in contractile function of rat hearts oxidizing acetoacetate

1 reference

12 December 2020

Relation between plasma free fatty acids and arrhythmias within the first twelve hours of acute myocardial infarction

1 reference

12 December 2020

Protection of the ischaemic myocardium by L-propionylcarnitine: effects on the recovery of cardiac output after ischaemia and reperfusion, carnitine transport, and fatty acid oxidation

1 reference

12 December 2020

Plasma catechol amine concentrations in myocardial infarction and angina pectoris

1 reference

12 December 2020

Lipids, hormones, and atherogenesis. The transport and utilization of free fatty acid

1 reference

12 December 2020

Antilipolytic therapy in angina pectoris. Reduction of exercise-induced ST segment depression

1 reference

12 December 2020

Protective effect of increased glycolytic substrate against systolic and diastolic dysfunction and increased coronary resistance from prolonged global underperfusion and reperfusion in isolated rabbit hearts perfused with erythrocyte suspensions

1 reference

12 December 2020

Protection of the ischaemic dog heart by oxfenicine

1 reference

12 December 2020

Effect of Free Fatty Acids on Myocardial Function and Oxygen Consumption in Intact Dogs

1 reference

12 December 2020

Etomoxir improves left ventricular performance of pressure-overloaded rat heart

1 reference

12 December 2020

Inhibition of carnitine palmitoyl-CoA transferase activity and fatty acid oxidation by lactate and oxfenicine in cardiac muscle

1 reference

12 December 2020

Hormone-sensitive lipase of adipose tissue

1 reference

12 December 2020

Initial metabolic and hormonal response to acute myocardial infarction.

1 reference

12 December 2020

Effects of trimetazidine on ischemic contracture in isolated perfused rat hearts

1 reference

12 December 2020

Alterations of carbohydrate and lipid metabolism in the acutely ischemic heart

1 reference

12 December 2020

Genetic studies on the arrhythmia in acute myocardial infarction with special reference to serum free fatty acid level

1 reference

12 December 2020

Effect of increased free fatty acids on myocardial oxygen extraction and angina threshold during atrial pacing.

1 reference

12 December 2020

Perhexiline maleate treatment for severe angina pectoris--correlations with pharmacokinetics

1 reference

12 December 2020

Electron transport chain defects in heart failure

1 reference

12 December 2020

Carnitine stimulation of glucose oxidation in the fatty acid perfused isolated working rat heart

1 reference

12 December 2020

Mechanism of action of oxfenicine on muscle metabolism

1 reference

12 December 2020

Control of insulin secretion by catecholamines, stress, and the sympathetic nervous system.

1 reference

12 December 2020

Modification of left ventricular hypertrophy by chronic etomixir treatment

1 reference

12 December 2020

Combination treatment with trimetazidine and diltiazem in stable angina pectoris

1 reference

12 December 2020

Dichloroacetate enhances myocardial functional and metabolic recovery following global ischemia

1 reference

12 December 2020

Two mechanisms produce tissue-specific inhibition of fatty acid oxidation by oxfenicine

1 reference

12 December 2020

The effect of dichloroacetate on the isolated no flow arrested rat heart

1 reference

12 December 2020

The effect of Oxfenicine on cardiac carbohydrate metabolism in intact dogs.

1 reference

12 December 2020

Modification of subcellular organelles in pressure-overloaded heart by etomoxir, a carnitine palmitoyltransferase I inhibitor.

1 reference

12 December 2020

Therapy of Angina Pectoris with Low-Dose Perhexiline

1 reference

12 December 2020

Glucose-insulin-potassium induced alterations in individual plasma free fatty acids in patients with acute myocardial infarction

1 reference

12 December 2020

Familial carnitine transporter defect: A treatable cause of cardiomyopathy in children

1 reference

12 December 2020

Plasma bilirubin and serum free fatty acids after myocardial infarction

1 reference

12 December 2020

Sera containing elevated nonesterified fatty acids from patients with angiographically documented coronary atherosclerosis cause marked lipid accumulation in cultured human arterial smooth muscle-derived cells.

1 reference

12 December 2020

Etomoxir, a carnitine palmitoyltransferase I inhibitor, protects hearts from fatty acid-induced ischemic injury independent of changes in long chain acylcarnitine

1 reference

12 December 2020

Comparison of trimetazidine with nifedipine in effort angina: a double-blind, crossover study

1 reference

12 December 2020

Effects of glucose and fatty acids on myocardial ischaemia and arrhythmias

1 reference

12 December 2020

Volume overload hypertrophy of the newborn heart slows the maturation of enzymes involved in the regulation of fatty acid metabolism

1 reference

12 December 2020

Dichloroacetate as metabolic therapy for myocardial ischemia and failure

1 reference

12 December 2020

Effects of an intravenous infusion of a potassium-glucose-insulin solution on the electrocardiographic signs of myocardial infarction. A preliminary clinical report

1 reference

12 December 2020

An imbalance between glycolysis and glucose oxidation is a possible explanation for the detrimental effects of high levels of fatty acids during aerobic reperfusion of ischemic hearts

1 reference

12 December 2020

L-propionyl-carnitine protection of mitochondria in ischemic rat hearts

1 reference

12 December 2020

Effect of antilipolysis on heart and skeletal muscle glucose uptake in overnight fasted humans.

1 reference

12 December 2020

Effect of Plasma Free Fatty Acid Lowering on Exercise Tolerance and ST Segment Depression in Patients with Angina Pectoris

1 reference

12 December 2020

Perhexiline maleate in the treatment of angina pectoris

1 reference

12 December 2020

Pyruvate dehydrogenase activity and malonyl CoA levels in normal and ischemic swine myocardium: effects of dichloroacetate.

1 reference

12 December 2020

Optimizing cardiac energy metabolism: how can fatty acid and carbohydrate metabolism be manipulated?

1 reference

12 December 2020

Increases in serum unbound free fatty acid levels following coronary angioplasty

1 reference

12 December 2020

Platelet function and plasma free fatty acids during acute myocardial infarction and severe angina pectoris

1 reference

12 December 2020

Effects of a new metabolic modulator, ranolazine, on exercise tolerance in angina pectoris patients treated with beta-blocker or diltiazem

1 reference

12 December 2020

Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiodarone.

1 reference

12 December 2020

Genetic disorders of carnitine metabolism and their nutritional management

1 reference

12 December 2020

Fatty acid and glucose utilization in isolated, working newborn pig hearts

1 reference

12 December 2020

Energy metabolism in the normal and failing heart: potential for therapeutic interventions

1 reference

12 December 2020

Cardioprotective effects of ranolazine (RS-43285) in the isolated perfused rabbit heart.

1 reference

12 December 2020

Cardiovascular pharmacology of perhexiline.

1 reference

12 December 2020

Modulation of alpha 1-adrenoceptors in rat left ventricle by ischaemia and acyl carnitines: protection by ranolazine

1 reference

12 December 2020

Effect of antilipolytic therapy on ST segment elevation during myocardial ischaemia in man

1 reference

12 December 2020

Beneficial effect of enhanced myocardial carbohydrate utilisation after oxfenicine (L-hydroxyphenylglycine) in angina pectoris

1 reference

12 December 2020

Chronic effects of trimetazidine on ergometric parameters in effort angina

1 reference

12 December 2020

Metabolic modulation of acute myocardial infarction. The ECLA (Estudios Cardiológicos Latinoamérica) Collaborative Group

1 reference

12 December 2020

Perhexiline induces generalized lipidosis in rats

1 reference

12 December 2020

Ranolazine increases active pyruvate dehydrogenase in perfused normoxic rat hearts: evidence for an indirect mechanism

1 reference

12 December 2020

First clinical trial with etomoxir in patients with chronic congestive heart failure

1 reference

12 December 2020

Mitochondrial dysfunction in heart failure: potential for therapeutic interventions?

1 reference

12 December 2020

Low-dose glucose-insulin-potassium is ineffective in acute myocardial infarction: results of a randomized multicenter Pol-GIK trial

1 reference

12 December 2020

Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions

1 reference

12 December 2020

Impaired oxidation of debrisoquine in patients with perhexiline liver injury

1 reference

12 December 2020

1 reference

12 December 2020

Fatty acid uptake in normal human myocardium

1 reference

12 December 2020

Modification of sarcoplasmic reticulum gene expression in pressure overload cardiac hypertrophy by etomoxir

1 reference

12 December 2020

CPT-1 inhibition by etomoxir has a chamber-related action on cardiac sarcoplasmic reticulum and isomyosins

1 reference

12 December 2020

Serum-free-fatty-acids after acute myocardial infarction and cerebral vascular occlusion

1 reference

12 December 2020

Effect of nicotinic acid on exogenous myocardial glucose utilization.

1 reference

12 December 2020

A controlled trial with a novel anti-ischemic agent, ranolazine, in chronic stable angina pectoris that is responsive to conventional antianginal agents. Ranolazine Study Group

1 reference

12 December 2020

Cardiac efficiency is improved after ischemia by altering both the source and fate of protons

1 reference

12 December 2020

Cardiac energetics during ischaemia and the rationale for metabolic interventions

1 reference

12 December 2020

Regulation of fatty acid oxidation in the mammalian heart in health and disease

1 reference

12 December 2020

Alterations of long-chain free fatty acid and magnesium concentrations in acute myocardial infarction

1 reference

12 December 2020

Oxfenicine diverts rat muscle metabolism from fatty acid to carbohydrate oxidation and protects the ischaemic rat heart

1 reference

12 December 2020

Propionyl-l-carnitine in intermittent claudication: Double-blind, placebo-controlled, dose titration, multicenter study

1 reference

12 December 2020

Promotion of carbohydrate oxidation in the heart by some phenylglyoxylic acids

1 reference

12 December 2020

Some biochemical aspects of the protective effect of trimetazidine on rat cardiomyocytes during hypoxia and reoxygenation

1 reference

12 December 2020

Glucose metabolism in the ischemic heart

1 reference

12 December 2020

Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart

1 reference

12 December 2020

Acute effects of trimetazidine on ergometric parameters in effort angina

1 reference

12 December 2020

Etomoxir: a new approach to treatment of chronic heart failure

1 reference

12 December 2020

Myocardial metabolic and hemodynamic effects of dichloroacetate in coronary artery disease

1 reference

12 December 2020

Mechanisms of fatty acid-induced inhibition of glucose uptake

1 reference

12 December 2020

Glucose and palmitate oxidation in isolated working rat hearts reperfused after a period of transient global ischemia

1 reference

12 December 2020

Plasma fatty acid levels in infants and adults after myocardial ischemia.

1 reference

12 December 2020

Effects of perhexiline on symptomatic and hemodynamic responses to exercise in patients with angina pectoris

1 reference

12 December 2020

Effects of Perhexiline on Coronary Hemodynamic and Myocardial Metabolic Responses to Tachycardia

1 reference

12 December 2020

Control of ventricular arrhythmias during myocardial infarction by antilipolytic treatment using a nicotinic-acid analogue

1 reference

12 December 2020

Gene regulatory mechanisms governing energy metabolism during cardiac hypertrophic growth

1 reference

12 December 2020

Importance of free fatty acids as a determinant of myocardial oxygen consumption and myocardial ischemic injury during norepinephrine infusion in dogs

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1015384710373

1 reference

Dimensions Publication ID

3 August 2017

1039646571

0 references

1 reference