(Q35105932)

25512404

6 August 2017

title

In vivo pharmacokinetics and pharmacodynamics of the lantibiotic NAI-107 in a neutropenic murine thigh infection model (English)

1 reference

6 August 2017

1 reference

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25512404%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Alexander J Lepak

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25512404%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Karen Marchillo

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25512404%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

William A Craig

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25512404%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

0 references

publication date

15 December 2014

1 reference

25512404

Antimicrobial Agents and Chemotherapy

6 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25512404%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

59

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25512404%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25512404%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

1258-1264

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25512404%20AND%20SRC:MED&resulttype=core&format=json

The Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane Functions

11 June 2020

cites work

1 reference

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9 July 2018

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Methicillin-resistant Staphylococcus aureus: an evolving pathogen

9 July 2018

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New antibiotics for bad bugs: where are we?

9 July 2018

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9 July 2018

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Inoculum effects of ceftobiprole, daptomycin, linezolid, and vancomycin with Staphylococcus aureus and Streptococcus pneumoniae at inocula of 10(5) and 10(7) CFU injected into opposite thighs of neutropenic mice

9 July 2018

1 reference

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9 July 2018

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9 July 2018

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Comparative pharmacodynamics of the new oxazolidinone tedizolid phosphate and linezolid in a neutropenic murine Staphylococcus aureus pneumonia model

9 July 2018

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New horizons for host defense peptides and lantibiotics

9 July 2018

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Methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci, and other Gram-positives in healthcare

9 July 2018

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Mechanisms of resistance and clinical relevance of resistance to β-lactams, glycopeptides, and fluoroquinolones

9 July 2018

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Combating antimicrobial resistance: policy recommendations to save lives

9 July 2018

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Efficacy of the new lantibiotic NAI-107 in experimental infections induced by multidrug-resistant Gram-positive pathogens

9 July 2018

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Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children: executive summary

9 July 2018

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The 10 x '20 Initiative: pursuing a global commitment to develop 10 new antibacterial drugs by 2020.

9 July 2018

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Waves of resistance: Staphylococcus aureus in the antibiotic era.

9 July 2018

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Methicillin-resistant Staphylococcus aureus central line-associated bloodstream infections in US intensive care units, 1997-2007.

9 July 2018

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Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America

9 July 2018

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Activities of clindamycin, daptomycin, doxycycline, linezolid, trimethoprim-sulfamethoxazole, and vancomycin against community-associated methicillin-resistant Staphylococcus aureus with inducible clindamycin resistance in murine thigh [...]

9 July 2018

1 reference

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What is in the pipeline for Gram-negative pathogens?

9 July 2018

1 reference

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The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America

9 July 2018

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Invasive methicillin-resistant Staphylococcus aureus infections in the United States

9 July 2018

1 reference

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A novel lantibiotic acting on bacterial cell wall synthesis produced by the uncommon actinomycete Planomonospora sp.

9 July 2018

1 reference

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Estimating health care-associated infections and deaths in U.S. hospitals, 2002

9 July 2018

1 reference

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Pharmacodynamics of a new cephalosporin, PPI-0903 (TAK-599), active against methicillin-resistant Staphylococcus aureus in murine thigh and lung infection models: identification of an in vivo pharmacokinetic-pharmacodynamic target

9 July 2018

1 reference

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Lipid II as a target for antibiotics

9 July 2018

1 reference

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Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America

9 July 2018

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Bacterial lantibiotics: strategies to improve therapeutic potential.

9 July 2018

1 reference

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Emergence of community-associated methicillin-resistant Staphylococcus aureus at a Memphis, Tennessee Children's Hospital

9 July 2018

1 reference

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The challenge of emerging and re-emerging infectious diseases

9 July 2018

1 reference

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9 July 2018

1 reference

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In vivo pharmacodynamic activity of daptomycin

9 July 2018

1 reference

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Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335879

Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335879

Role of lipid-bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics

9 July 2018

1 reference

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In vivo activities of amoxicillin and amoxicillin-clavulanate against Streptococcus pneumoniae: application to breakpoint determinations.

9 July 2018

1 reference

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The perpetual challenge of infectious diseases

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335879

27 September 2018

The bacteria fight back

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335879

Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335879

Nisin, alone and combined with peptidoglycan-modulating antibiotics: activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335879

Lipid II induces a transmembrane orientation of the pore-forming peptide lantibiotic nisin

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335879

Vancomycin-Resistant Enterococci

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335879

Antibiotics at the crossroads

16 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25512404

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antibiotic resistance and antibiotic development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25512404

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.04444-14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25512404%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25512404%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

25512404

1 reference