(Q35111132)

6 August 2017

title

A single phosphorodiamidate morpholino oligomer targeting VP24 protects rhesus monkeys against lethal Ebola virus infection (English)

1 reference

6 August 2017

main subject

Orthoebolavirus zairense

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10

Sina Bavari

1 reference

6 August 2017

2

Chris A Whitehouse

1 reference

6 August 2017

Travis K Warren

1

1 reference

6 August 2017

Jay Wells

3

1 reference

6 August 2017

Lisa Welch

4

1 reference

6 August 2017

Alison E Heald

5

1 reference

6 August 2017

Jay S Charleston

6

1 reference

6 August 2017

Pete Sazani

7

1 reference

6 August 2017

St Patrick Reid

8

1 reference

6 August 2017

Patrick L Iversen

9

1 reference

6 August 2017

publication date

10 February 2015

1 reference

6 August 2017

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6 August 2017

volume

6

1 reference

6 August 2017

issue

1

1 reference

Safety and pharmacokinetic profiles of phosphorodiamidate morpholino oligomers with activity against ebola virus and marburg virus: results of two single-ascending-dose studies

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

The Ebola epidemic: a global health emergency

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

A novel life cycle modeling system for Ebola virus shows a genome length-dependent role of VP24 in virus infectivity

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

Emergence of Zaire Ebola Virus Disease in Guinea

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

Filoviral immune evasion mechanisms

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

Correlates of immunity to filovirus infection

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

VP24 is a molecular determinant of Ebola virus virulence in guinea pigs.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

9 July 2018

Ebola haemorrhagic fever

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

Advanced antisense therapies for postexposure protection against lethal filovirus infections.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

Hemorrhagic fever viruses as biological weapons: medical and public health management

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

The Ebola virus VP35 protein functions as a type I IFN antagonist.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337572

9 July 2018

Identifiers

DOI

10.1128/MBIO.02344-14

1 reference

6 August 2017

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6 August 2017

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