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An unraveling tale of how integrins are activated from within.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12707006
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12707006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
An unraveling tale of how integrins are activated from within
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12707006
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12707006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
author
Mark A. Travis
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12707006
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12707006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
author name string
Jonathan D Humphries
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12707006
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12707006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
Martin J Humphries
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12707006
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12707006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
publication date
1 April 2003
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12707006
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12707006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
published in
Trends in Pharmacological Sciences
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12707006
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12707006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
volume
24
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12707006
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12707006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
issue
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12707006
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12707006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
page(s)
192-197
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12707006
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12707006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
cites work
Integrin structure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrins: bidirectional, allosteric signaling machines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conformational regulation of integrin structure and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms contributing to the activity of integrins on leukocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-integrin as novel drug-discovery targets: potential therapeutic and diagnostic implications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin antagonists
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A membrane-distal segment of the integrin alpha IIb cytoplasmic domain regulates integrin activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Divalent Cations Differentially Regulate Integrin αIIbCytoplasmic Tail Binding to β3and to Calcium- and Integrin-binding Protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oligomerization of the integrin alphaIIbbeta3: roles of the transmembrane and cytoplasmic domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A structural basis for integrin activation by the cytoplasmic tail of the alpha IIb-subunit
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three-dimensional model of the human platelet integrin alpha IIbbeta 3 based on electron cryomicroscopy and x-ray crystallography
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GALLEX, a measurement of heterologous association of transmembrane helices in a biological membrane
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Breaking the integrin hinge. A defined structural constraint regulates integrin signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of the membrane proximal regions of the alpha and beta subunit cytoplasmic domains constrains an integrin in the inactive state
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The phosphotyrosine binding-like domain of talin activates integrins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural determinants of integrin recognition by talin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The inner world of cell adhesion: integrin cytoplasmic domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Determination of the Border between the Transmembrane and Cytoplasmic Domains of Human Integrin Subunits
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin activation and structural rearrangement
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the extracellular segment of integrin alpha Vbeta3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of cell migration that inhibit intracellular paxillin/alpha4 binding: a well-documented use of positional scanning libraries
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900069-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0165-6147(03)00069-5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12707006
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12707006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
PubMed publication ID
12707006
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12707006
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12707006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
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