(Q35112115)

6 August 2017

1 reference

title

Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal (English)

1 reference

6 August 2017

1 reference

multiple drug resistance

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12708468

antineoplastic resistance

26 December 2023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12708468

26 December 2023

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01345.X

26 December 2023

4

Naoya Fujita

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12708468

26 December 2023

author name string

Takashi Tsuruo

1

1 reference

6 August 2017

Mikihiko Naito

2

1 reference

6 August 2017

Akihiro Tomida

3

1 reference

6 August 2017

Tetsuo Mashima

5

1 reference

6 August 2017

Hiroshi Sakamoto

6

1 reference

6 August 2017

Naomi Haga

7

1 reference

6 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12708468

26 December 2023

publication date

1 January 2003

1 reference

full work available at URL

6 August 2017

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1349-7006.2003.tb01345.x

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12708468

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1349-7006.2003.tb01345.x

26 December 2023

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01345.X

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1349-7006.2003.tb01345.x

26 December 2023

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01345.X

26 December 2023

1 reference

6 August 2017

volume

94

1 reference

6 August 2017

issue

1

1 reference

6 August 2017

page(s)

15-21

1 reference

Mechanisms of multidrug resistance and implications for therapy

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Regression of established tumors expressing P-glycoprotein by combinations of adriamycin, cyclosporin derivatives, and MRK-16 antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

The unfolded protein response in nutrient sensing and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Proteasome inhibition: a novel approach to cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

SUMO-1 conjugation to intact DNA topoisomerase I amplifies cleavable complex formation induced by camptothecin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Induction of apoptosis by cancer chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Resistance to antitumor agent-induced apoptosis in a mutant of human myeloid leukemia U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Esterification of reduced glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Methylglyoxal enhances cisplatin-induced cytotoxicity by activating protein kinase Cdelta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGE

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Modulation of heat-shock protein 27 (Hsp27) anti-apoptotic activity by methylglyoxal modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

The PI3K-PDK1 connection: more than just a road to PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Modulation of Akt kinase activity by binding to Hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Ansamycin antibiotics inhibit Akt activation and cyclin D expression in breast cancer cells that overexpress HER2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Topotecan inhibits VEGF- and bFGF-induced vascular endothelial cell migration via downregulation of the PI3K-Akt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01345.X

Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies

21 January 2018

3

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01345.X

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil

26 December 2023

6

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01345.X

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

26 December 2023

12

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01345.X

Drug resistance mediated by cellular stress response to the microenvironment of solid tumors

26 December 2023

18

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01345.X

Coinduction of glucose-regulated proteins and doxorubicin resistance in Chinese hamster cells

26 December 2023

20

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01345.X

Cellular resistance to topoisomerase poisons

26 December 2023

22

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01345.X

Glucose-regulated stresses cause degradation of DNA topoisomerase IIalpha by inducing nuclear proteasome during G1 cell cycle arrest in cancer cells

26 December 2023

23

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01345.X

Glucose starvation and hypoxia induce nuclear accumulation of proteasome in cancer cells

26 December 2023

26

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01345.X

Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis

26 December 2023

46

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01345.X

26 December 2023

Identifiers

1 reference

release_ocuxhfkyfzggrhr6xwft3xrk54

6 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ocuxhfkyfzggrhr6xwft3xrk54

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference