(Q35118813)

6 August 2017

1 reference

title

The reversal of multidrug resistance: an update (English)

1 reference

6 August 2017

multiple drug resistance

1 reference

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

29 December 2023

author name string

John A. Kellen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12724854

29 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12724854

29 December 2023

publication date

1 January 2003

1 reference

full work available at URL

6 August 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1359-4117.2003.01067.x

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1359-4117.2003.01067.x

29 December 2023

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Journal of Experimental Therapeutics & Oncology

29 December 2023

published in

1 reference

6 August 2017

3

1 reference

6 August 2017

5-13

1 reference

6 August 2017

1

1 reference

Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs

6 August 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Multidrug resistance in oncology: diagnostic and therapeutic approaches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Calcein assay for multidrug resistance reliably predicts therapy response and survival rate in acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Anti-psychotic drugs reverse multidrug resistance of tumor cell lines and human AML cells ex-vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

A novel areneisonitrile Tc complex inhibits the transport activity of MDR P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Synthesis of C-ring aromatic taxoids and evaluation of their multi-drug resistance reversing activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Bromocriptine modulates P-glycoprotein function

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

PKC-independent modulation of multidrug resistance in cells with mutant (V185) but not wild-type (G185) P-glycoprotein by bryostatin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Estrone and 17beta-estradiol reverse breast cancer resistance protein-mediated multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Dipyridamole-mediated reversal of multidrug resistance in MRP over-expressing human lung carcinoma cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Potent interaction of flavopiridol with MRP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Increase in doxorubicin cytotoxicity by carvedilol inhibition of P-glycoprotein activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Halogenated chalcones with high-affinity binding to P-glycoprotein: potential modulators of multidrug resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Inhibition of P-glycoprotein activity and chemosensitization of multidrug-resistant ovarian carcinoma 2780AD cells by hexanoylglucosylceramide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

IL-4 inhibits P-glycoprotein in normal and malignant NK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Reversal of multidrug resistance (MDR) by aspidofractinine-type indole alkaloids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Reversal effects of antifungal drugs on multidrug resistance in MDR1-overexpressing HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Linear and cyclic peptides as substrates and modulators of P-glycoprotein: peptide binding and effects on drug transport and accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Reversal of resistance in multidrug resistance protein (MRP1)-overexpressing cells by LY329146.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Reversal of multidrug resistance by the P-glycoprotein modulator, LY335979, from the bench to the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Methylene blue reverts multidrug resistance: sensitivity of multidrug resistant cells to this dye and its photodynamic action

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

P-glycoprotein inhibition by the multidrug resistance-reversing agent MS-209 enhances bioavailability and antitumor efficacy of orally administered paclitaxel

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Total synthesis of ningalin B utilizing a heterocyclic azadiene Diels-Alder reaction and discovery of a new class of potent multidrug resistant (MDR) reversal agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Reversion of multidrug resistance with polyalkylcyanoacrylate nanoparticles: towards a mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

The synthesis and evaluation of a solution phase indexed combinatorial library of non-natural polyenes for reversal of P-glycoprotein mediated multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

HIV protease inhibitor ritonavir: a more potent inhibitor of P-glycoprotein than the cyclosporine analog SDZ PSC 833.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Novel cellular determinants for reversal of multidrug resistance in cells expressing P170-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Inhibition of P-glycoprotein activity and reversal of multidrug resistance in vitro by rosemary extract.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Phase I clinical and pharmacokinetic study of S9788, a new multidrug-resistance reversal agent given alone and in combination with doxorubicin to patients with advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Reversal of multidrug resistance by novel nitrophenyl pyrones, SNF4435C and D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Circumvention of P-glycoprotein-mediated multidrug resistance by S16020-2: kinetics of uptake and efflux in sensitive and resistant cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Reversal of multidrug resistance by the staurosporine derivatives CGP 41251 and CGP 42700.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Syntheses of taxuspine C derivatives as functional inhibitors of P-glycoprotein, an ATP-associated cell-membrane transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

In vitro and in vivo reversal of cancer cell multidrug resistance by the semi-synthetic antibiotic tiamulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Interaction of omeprazole, lansoprazole and pantoprazole with P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Discovery and biological evaluation of a new family of potent modulators of multidrug resistance: reversal of multidrug resistance of mouse lymphoma cells by new natural jatrophane diterpenoids isolated from Euphorbia species

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Thermal dependence of multidrug-resistant-modulator efficiency: a study in anionic liposomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Influence of cell concentration in limiting the therapeutic benefit of P-glycoprotein reversal agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

The major vault protein (MVP), a new multidrug resistance associated protein, is frequently expressed in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Drugs as P-glycoprotein substrates, inhibitors, and inducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Synthesis and pharmacological activity of the stereoisomers of GP-88, a propafenone-type modulator of multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Studies on propafenone-type modulators of multidrug resistance VI. Synthesis and pharmacological activity of compounds with varied spacer length between the central aromatic ring and the nitrogen atom

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

Pregnane Glycoside Multidrug-Resistance Modulators fromCynanchumwilfordii

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1359-4117.2003.01067.X

From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance.

21 January 2018

5

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Aureobasidins as new inhibitors of P-glycoprotein in multidrug resistant tumor cells

29 December 2023

12

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Reversal of P-glycoprotein-mediated multidrug resistance in vitro by AV200, a new ardeemin derivative

29 December 2023

13

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Inhibition of P-glycoprotein ATPase activity by beryllium fluoride

29 December 2023

14

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Characterization of a novel bisacridone and comparison with PSC 833 as a potent and poorly reversible modulator of P-glycoprotein.

29 December 2023

15

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Modulation of multidrug resistance by cepharanthine in fresh human gastrointestinal tumor cells

29 December 2023

22

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Synthesis of a series of 3-cyanopropionamides and 4-imino-gamma-butyrolactams and evaluation of their function as modulators of multidrug resistance

29 December 2023

23

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Inhibition of P-glycoprotein by cyclosporin A analogues and metabolites.

29 December 2023

24

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Newly synthesized dihydropyridine derivatives as modulators of P-glycoprotein-mediated multidrug resistance

29 December 2023

29

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Reversal of multidrug resistance by kopsiflorine isolated from Kopsia dasyrachis

29 December 2023

42

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

L-Canavanine modulates cellular growth, chemosensitivity and P-glycoprotein substrate accumulation in cultured human tumor cell lines

29 December 2023

45

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Mechanism of sensitization of MDR cancer cells by Pluronic block copolymers: Selective energy depletion

29 December 2023

57

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Multidrug-resistance modulators from Stephania japonica

29 December 2023

72

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

New taxanes as highly efficient reversal agents for multi-drug resistance in cancer cells

29 December 2023

73

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Torilin, a Sesquiterpene fromTorilis japonica, Reverses Multidrug-Resistance in Cancer Cells

29 December 2023

77

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Overcoming of multidrug resistance by VA-033, a novel derivative of apovincaminic acid ester

29 December 2023

78

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Studies on quinazolinones as dual inhibitors of Pgp and MRP1 in multidrug resistance

29 December 2023

81

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Reversal of P-glycoprotein mediated multidrug resistance by novel anthranilamide derivatives

29 December 2023

83

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Outwitting drug resistance requires researchers to take many different tacks

29 December 2023

85

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

The human multidrug resistance P-glycoprotein is inactive when its maturation is inhibited: potential for a role in cancer chemotherapy

29 December 2023

90

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Role of human CYP3A and P-glycoprotein on the absorption of drugs

29 December 2023

91

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Is there less resistance on the chemoresistance front?

29 December 2023

93

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

Overcoming drug resistance: targeting more than one site

29 December 2023

95

1 reference

https://api.crossref.org/works/10.1046/J.1359-4117.2003.01067.X

29 December 2023

Identifiers

1 reference

release_iqhf5lvo5rdejmspyef4236rt4

6 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/iqhf5lvo5rdejmspyef4236rt4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference