(Q35119508)

6 August 2017

1 reference

title

Aging as war between chemical and biochemical processes: protein methylation and the recognition of age-damaged proteins for repair (English)

1 reference

6 August 2017

Aging as war between chemical and biochemical processes: Protein methylation and the recognition of age-damaged proteins for repair (English)

1 reference

https://api.crossref.org/works/10.1016/S1568-1637(03)00011-4

29 December 2023

1 reference

1 reference

https://api.crossref.org/works/10.1016/S1568-1637(03)00011-4

29 December 2023

1 reference

https://api.crossref.org/works/10.1016/S1568-1637(03)00011-4

29 December 2023

1 reference

https://api.crossref.org/works/10.1016/S1568-1637(03)00011-4

29 December 2023

1 reference

https://api.crossref.org/works/10.1016/S1568-1637(03)00011-4

29 December 2023

author name string

Steven Clarke

series ordinal

1

1 reference

6 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12726775

29 December 2023

publication date

1 July 2003

1 reference

full work available at URL

6 August 2017

https://api.elsevier.com/content/article/PII:S1568163703000114?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S1568-1637(03)00011-4

https://api.elsevier.com/content/article/PII:S1568163703000114?httpAccept=text/plain

29 December 2023

1 reference

https://api.crossref.org/works/10.1016/S1568-1637(03)00011-4

29 December 2023

published in

Ageing Research Reviews

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6 August 2017

2

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6 August 2017

3

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6 August 2017

263-285

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Isoaspartate in peptides and proteins: formation, significance, and analysis

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

The influence of protein structure on the products emerging from succinimide hydrolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Ubiquitin-mediated proteolysis in learning and memory

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Extension of the Drosophila lifespan by overexpression of a protein repair methyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Deamidation of asparagine in a major histocompatibility complex-bound peptide affects T cell recognition but does not explain type B reactivity

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Propensity for spontaneous succinimide formation from aspartyl and asparaginyl residues in cellular proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

UVA irradiation induces L-isoaspartyl formation in melanoma cell proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Isoaspartate in chrondroitin sulfate proteoglycans of mammalian brain

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Polymorphic forms of the protein L-isoaspartate (D-aspartate) O-methyltransferase involved in the repair of age-damaged proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Altered levels of S-adenosylmethionine and S-adenosylhomocysteine in the brains of L-isoaspartyl (D-Aspartyl) O-methyltransferase-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Simultaneous stereoinversion and isomerization at specific aspartic acid residues in alpha A-crystallin from human lens

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

The presence of D-beta-aspartic acid-containing peptides in elastic fibers of sun-damaged skin: a potent marker for ultraviolet-induced skin aging.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Synthesis, aggregation, and neurotoxicity of the Alzheimer's Abeta1-42 amyloid peptide and its isoaspartyl isomers

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Protein damage and methylation-mediated repair in the erythrocyte

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Folate status and age affect the accumulation of L-isoaspartyl residues in rat liver proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Crystal structure of a protein repair methyltransferase from Pyrococcus furiosus with its L-isoaspartyl peptide substrate

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Repair of oxidized proteins. Identification of a new methionine sulfoxide reductase

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Protein isoaspartyl methyltransferase protects from Bax-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

A highly active protein repair enzyme from an extreme thermophile: the L-isoaspartyl methyltransferase from Thermotoga maritima

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Aberrant synaptic transmission in the hippocampal CA3 region and cognitive deterioration in protein-repair enzyme-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Increased membrane-protein methylation in hereditary spherocytosis. A marker of cytoskeletal disarray

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Increased methyl esterification of altered aspartyl residues in erythrocyte membrane proteins in response to oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Protein methylation as a marker of aspartate damage in glucose-6-phosphate dehydrogenase-deficient erythrocytes: role of oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Comparing mutants, selective breeding, and transgenics in the dissection of aging processes of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Molecular phylogenetics of a protein repair methyltransferase.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Targeted gene disruption of the Caenorhabditis elegans L-isoaspartyl protein repair methyltransferase impairs survival of dauer stage nematodes

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Phenotypic analysis of seizure-prone mice lacking L-isoaspartate (D-aspartate) O-methyltransferase.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Age-induced protein modifications and increased proteolysis in potato seed-tubers

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Methylation of atypical protein aspartyl residues during the stress response of HeLa cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Down-regulation of protein L-isoaspartyl methyltransferase in human epileptic hippocampus contributes to generation of damaged tubulin

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Age-dependent deamidation of asparagine residues in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Determination of two sites of automethylation in bovine erythrocyte protein (D-aspartyl/L-isoaspartyl) carboxyl methyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Limited accumulation of damaged proteins in l-isoaspartyl (D-aspartyl) O-methyltransferase-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Alternative splicing of the human isoaspartyl protein carboxyl methyltransferase RNA leads to the generation of a C-terminal -RDEL sequence in isozyme II

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Isoaspartyl post-translational modification triggers autoimmune responses to self-proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Methylation at D-aspartyl residues in erythrocytes: possible step in the repair of aged membrane proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Conversion of isoaspartyl peptides to normal peptides: implications for the cellular repair of damaged proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

The fidelity of protein synthesis: can mischarging by aspartyl-tRNA(Asp) synthetase lead to the formation of isoaspartyl residues in proteins?

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Protein repair L-isoaspartyl methyltransferase in plants. Phylogenetic distribution and the accumulation of substrate proteins in aged barley seeds

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Molecular aging of tubulin: accumulation of isoaspartyl sites in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Do damaged proteins accumulate in Caenorhabditis elegans L-isoaspartate methyltransferase (pcm-1) deletion mutants?

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Complex interactions of the protein L-isoaspartyl methyltransferase and calmodulin revealed with the yeast two-hybrid system

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Spontaneous alterations in the covalent structure of synapsin I during in vitro aging.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

The type II isoform of bovine brain protein L-isoaspartyl methyltransferase has an endoplasmic reticulum retention signal (...RDEL) at its C-terminus

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Neighboring side chain effects on asparaginyl and aspartyl degradation: an ab initio study of the relationship between peptide conformation and backbone NH acidity

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

1 reference

7 January 2021

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

1 reference

7 January 2021

High-quality life extension by the enzyme peptide methionine sulfoxide reductase

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Crystal structure of human L-isoaspartyl methyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Spontaneous deamidation and isomerization of Asn108 in prion peptide 106-126 and in full-length prion protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Enzymes that catalyse the restructuring of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Exceptional Seed Longevity and Robust Growth: Ancient Sacred Lotus from China

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Isoaspartate formation and neurodegeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Isoaspartate formation at position 23 of amyloid beta peptide enhanced fibril formation and deposited onto senile plaques and vascular amyloids in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Crystal structure of protein isoaspartyl methyltransferase: a catalyst for protein repair

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Crystal structure of human L-isoaspartyl-O-methyl-transferase with S-adenosyl homocysteine at 1.6-A resolution and modeling of an isoaspartyl-containing peptide at the active site

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Specific glutamine and asparagine residues of gamma-S crystallin are resistant to in vivo deamidation

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Ca2+-free calmodulin and calmodulin damaged by in vitro aging are selectively degraded by 26 S proteasomes without ubiquitination.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Distinct patterns of expression but similar biochemical properties of protein L-isoaspartyl methyltransferase in higher plants

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Protein repair methyltransferase from the hyperthermophilic archaeon Pyrococcus furiosus. Unusual methyl-accepting affinity for D-aspartyl and N-succinyl-containing peptides

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Repair, refold, recycle: how bacteria can deal with spontaneous and environmental damage to proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Mutations in the Escherichia coli surE gene increase isoaspartyl accumulation in a strain lacking the pcm repair methyltransferase but suppress stress-survival phenotypes

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Deamidation and isoaspartate formation in smeared tau in paired helical filaments. Unusual properties of the microtubule-binding domain of tau.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Detection and characterization of a protein isoaspartyl methyltransferase which becomes trapped in the extracellular space during blood vessel injury

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Injury-induced enzymatic methylation of aging collagen in the extracellular matrix of blood vessels

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Measurement of altered aspartyl residues in the scrapie associated form of prion protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Deficiency in protein L-isoaspartyl methyltransferase results in a fatal progressive epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Structural integrity of histone H2B in vivo requires the activity of protein L-isoaspartate O-methyltransferase, a putative protein repair enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-1637%2803%2900011-4

7 January 2021

Human erythrocyte protein L-isoaspartyl methyltransferase: heritability of basal activity and genetic polymorphism for thermal stability

series ordinal

15

1 reference

https://api.crossref.org/works/10.1016/S1568-1637(03)00011-4

Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation

29 December 2023

series ordinal

24

1 reference

https://api.crossref.org/works/10.1016/S1568-1637(03)00011-4

29 December 2023

Identifiers

1 reference

6 August 2017

1 reference