(Q35121026)

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Thalidomide Analogues Suppress Lipopolysaccharide-Induced Synthesis of TNF-α and Nitrite, an Intermediate of Nitric Oxide, in a Cellular Model of Inflammation

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Europe PubMed Central

PubMed publication ID

6 August 2017

Thalidomide Analogues Suppress Lipopolysaccharide-Induced Synthesis of TNF-α and Nitrite, an Intermediate of Nitric Oxide, in a Cellular Model of Inflammation (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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lipopolysaccharide

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author name string

David Tweedie

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Kathryn A Frankola

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Weiming Luo

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Yazhou Li

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Nigel H Greig

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

publication date

19 July 2011

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

The Open Biochemistry Journal

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

37-44

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Tumor necrosis factor-α synthesis inhibitor, 3,6'-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice

1 reference

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28 July 2018

Lenalidomide - current understanding of mechanistic properties

1 reference

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1 reference

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28 July 2018

Targeting TNF-α to elucidate and ameliorate neuroinflammation in neurodegenerative diseases

1 reference

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Thalidomide and analogues: potential for immunomodulation of inflammatory and neoplastic dermatologic disorders

1 reference

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28 July 2018

Effect of thalidomide on nitric oxide production in lipopolysaccharide-activated RAW 264.7 cells.

1 reference

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Activated macrophages as a novel determinant of tumor cell radioresponse: the role of nitric oxide-mediated inhibition of cellular respiration and oxygen sparing.

1 reference

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28 July 2018

Pharmacological properties of thalidomide and its analogues

1 reference

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28 July 2018

Cyclooxygenase-1 null mice show reduced neuroinflammation in response to beta-amyloid

1 reference

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Does neuroinflammation fan the flame in neurodegenerative diseases?

1 reference

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Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention

1 reference

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28 July 2018

Peripheral chemo-cytokine profiles in Alzheimer's and Parkinson's diseases

1 reference

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28 July 2018

A cellular model of inflammation for identifying TNF-alpha synthesis inhibitors

1 reference

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28 July 2018

Physiological and pathological role of alpha-synuclein in Parkinson's disease through iron mediated oxidative stress; the role of a putative iron-responsive element

1 reference

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28 July 2018

Expression of amyotrophic lateral sclerosis-linked SOD1 mutant increases the neurotoxic potential of microglia via TLR2.

1 reference

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28 July 2018

New drugs in multiple myeloma: mechanisms of action and phase I/II clinical findings.

1 reference

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28 July 2018

Inflammatory cytokines increase mitochondrial damage in motoneuronal cells expressing mutant SOD1.

1 reference

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28 July 2018

Perispinal etanercept produces rapid improvement in primary progressive aphasia: identification of a novel, rapidly reversible TNF-mediated pathophysiologic mechanism

1 reference

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28 July 2018

Lenalidomide and its role in the management of multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141331

28 July 2018

Critical roles of the p110 beta subtype of phosphoinositide 3-kinase in lipopolysaccharide-induced Akt activation and negative regulation of nitrite production in RAW 264.7 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141331

28 July 2018

Perispinal Etanercept for Treatment of Alzheimers Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141331

28 July 2018

TNF-alpha inhibition as a treatment strategy for neurodegenerative disorders: new drug candidates and targets.

1 reference

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28 July 2018

Neuroinflammation in Alzheimer's disease and Parkinson's disease: are microglia pathogenic in either disorder?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141331

28 July 2018

Synuclein activates microglia in a model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141331

28 July 2018

The thalidomide saga

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141331

28 July 2018

Microglial control of neuronal death and synaptic properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141331

28 July 2018

The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease

1 reference

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28 July 2018

Role of microglia in the central nervous system's immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141331

28 July 2018

Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles

1 reference

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28 July 2018

Metal and inflammatory targets for Alzheimer's disease

1 reference

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28 July 2018

Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pat

1 reference

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28 July 2018

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

1 reference

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MAPK and JNK transduction pathways can phosphorylate Sp1 to activate the uPA minimal promoter element and endogenous gene transcription

1 reference

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28 July 2018

Thiothalidomides: Novel Isosteric Analogues of Thalidomide with Enhanced TNF-α Inhibitory Activity

1 reference

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28 July 2018

Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis

1 reference

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28 July 2018

Microglia and macrophages in the developing CNS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141331

28 July 2018

Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

1 reference

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Regulation of c-Myc through phosphorylation at Ser-62 and Ser-71 by c-Jun N-terminal kinase

1 reference

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28 July 2018

Neuroinflammatory processes are important in neurodegenerative diseases: an hypothesis to explain the increased formation of reactive oxygen and nitrogen species as major factors involved in neurodegenerative disease development

1 reference

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28 July 2018

The role of microglia and macrophages in the pathophysiology of the CNS.

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28 July 2018

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28 July 2018

Tumor necrosis factor alpha-induced activation of c-jun N-terminal kinase is mediated by TRAF2.

1 reference

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28 July 2018

Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation

1 reference

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28 July 2018

p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1.

1 reference

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28 July 2018

Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase

1 reference

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28 July 2018

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141331

28 July 2018

Thalidomide resistance is based on the capacity of the glutathione-dependent antioxidant defense.

1 reference

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2009 Alzheimer's disease facts and figures

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The role of neuroimmunomodulation in Alzheimer's disease.

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27 September 2018

Restraining tumor necrosis factor-alpha by thalidomide prevents the amyloid beta-induced impairment of recognition memory in mice

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27 September 2018

Thalidomide suppressed interleukin-6 but not tumor necrosis factor-alpha in volunteers with experimental endotoxemia

1 reference

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27 September 2018

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease

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27 September 2018

Thalidomide-based TNF-alpha inhibitors for neurodegenerative diseases

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27 September 2018

Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis.

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27 September 2018

Inhibition of JNK activation through NF-kappaB target genes

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Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis

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Cytotoxicity of microglia

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27 September 2018

Thalidomide suppressed IL-1beta while enhancing TNF-alpha and IL-10, when cells in whole blood were stimulated with lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/21792375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of nitrite and nitrate in murine macrophage cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/21792375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 and tumor necrosis factor-alpha synergistically mediate neurotoxicity: involvement of nitric oxide and of N-methyl-D-aspartate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21792375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21792375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2174/1874091X01105010037

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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