(Q35122162)

6 August 2017

1 reference

title

Gene transfer approaches for the treatment of inflammatory bowel disease (English)

1 reference

inflammatory bowel diseases

6 August 2017

main subject

0 references

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3302013

30 December 2023

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3302013

30 December 2023

1

S. Wirtz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12732871

30 December 2023

author name string

M. F. Neurath

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12732871

30 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12732871

30 December 2023

publication date

1 May 2003

1 reference

full work available at URL

6 August 2017

https://www.nature.com/articles/3302013.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12732871

https://www.nature.com/articles/3302013.pdf

30 December 2023

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3302013

https://www.nature.com/articles/3302013

30 December 2023

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3302013

30 December 2023

1 reference

6 August 2017

volume

10

1 reference

6 August 2017

issue

10

1 reference

6 August 2017

page(s)

854-860

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Inflammatory Bowel Disease

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

21 January 2018

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Animal models of intestinal inflammation: new insights into the molecular pathogenesis and immunotherapy of inflammatory bowel disease

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Prospects for research in inflammatory bowel disease

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Biologic therapy of inflammatory bowel disease.

21 January 2018

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Inflammatory bowel disease: etiology and pathogenesis

21 January 2018

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The role of Th1/Th2 polarization in mucosal immunity

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The immunologic basis of inflammatory bowel disease

21 January 2018

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Reciprocal IFN-gamma and TGF-beta responses regulate the occurrence of mucosal inflammation

21 January 2018

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

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Genes, microbes, and T cells--new therapeutic targets in Crohn's disease

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Binding and Functional Comparisons of Two Types of Tumor Necrosis Factor Antagonists

21 January 2018

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Mesenteric lymph nodes are critical for the induction of high-dose oral tolerance in the absence of Peyer's patches.

21 January 2018

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Antiadhesion molecule therapy in inflammatory bowel disease

21 January 2018

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Antibodies to interleukin 12 abrogate established experimental colitis in mice

21 January 2018

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Induction and maintenance of clinical remission by interferon-beta in patients with steroid-refractory active ulcerative colitis-an open long-term pilot trial.

21 January 2018

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Interleukin 10 (Tenovil) in the prevention of postoperative recurrence of Crohn's disease

21 January 2018

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Absence of efficacy of subcutaneous antisense ICAM-1 treatment of chronic active Crohn's disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial

21 January 2018

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Disseminated cytomegalovirus infection in Crohn's disease following anti-tumour necrosis factor therapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Improving access to intestinal stem cells as a step toward intestinal gene transfer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Retargeting the coxsackievirus and adenovirus receptor to the apical surface of polarized epithelial cells reveals the glycocalyx as a barrier to adenovirus-mediated gene transfer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Efficient gene delivery to the inflamed colon by local administration of recombinant adenoviruses with normal or modified fibre structure

21 January 2018

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Gut epithelial cells as targets for gene therapy of hemophilia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Apical gene transfer into quiescent human and canine polarized intestinal epithelial cells by lentivirus vectors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Peroral gene therapy of lactose intolerance using an adeno-associated virus vector

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

In vivo and in vitro gene transfer and expression in rat intestinal epithelial cells by E1-deleted adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Role of integrin expression in adenovirus-mediated gene delivery to the intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Adenovirus-mediated transduction of intestinal cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Mucus altering agents as adjuncts for nonviral gene transfer to airway epithelium

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Hot topics in adeno-associated virus as a gene transfer vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Adenoviruses as gene-delivery vehicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

An intra-Peyer's patch gene transfer model for studying mucosal tolerance: distinct roles of B7 and IL-12 in mucosal T cell tolerance

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Cell receptors involved in adenovirus entry

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Adenoviral-mediated gene transfer in lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Gastrointestinal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Maintenance of functional stem cells in isolated and cultured adult intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Intestinal function and morphology after ex vivo irradiated small bowel transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

The role of M cells in mucosal immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Epithelial M cells: differentiation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Exploiting M cells for drug and vaccine delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Cloning of a new cytokine that induces IFN-gamma production by T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

IL-18-binding protein expression by endothelial cells and macrophages is up-regulated during active Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB.

21 January 2018

1 reference

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Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Treatment of T cell-dependent experimental colitis in SCID mice by local administration of an adenovirus expressing IL-18 antisense mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Blockade of endogenous IL-18 ameliorates TNBS-induced colitis by decreasing local TNF-alpha production in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Blockade of interleukin 6 trans signaling suppresses T-cell resistanceagainst apoptosis in chronic intestinal inflammation: Evidence in Crohn diseaseand experimental colitis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Cytokine directed therapy in scleroderma: rationale, current status, and the future

21 January 2018

1 reference

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TGF-beta in infections and infectious diseases

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Interleukin-10-deficient mice develop chronic enterocolitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Regulatory T cells and inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Role of interleukin-10 in a murine model of dextran sulfate sodium-induced colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Intra-articular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Interleukin 10 gene transfer prevents experimental colitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

IL-10 gene therapy prevents TNBS-induced colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

The prevention and treatment of murine colitis using gene therapy with adenoviral vectors encoding IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Treatment of murine colitis by Lactococcus lactis secreting interleukin-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Treatment of Crohn's disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Prevention of colitis by interleukin 10-transduced T lymphocytes in the SCID mice transfer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

Commensal bacteria as targets in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

Induction of Nod2 in Myelomonocytic and Intestinal Epithelial Cells via Nuclear Factor-κB Activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

Transmembrane TNF-alpha, induction of apoptosis, and the efficacy of TNF-targeting therapies in Crohn's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

Tumor necrosis factor-receptor 2 is up-regulated on lamina propria T cells in Crohn's disease and promotes experimental colitis in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

Tumor necrosis factor antagonist therapy and lymphoma development: twenty-six cases reported to the Food and Drug Administration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

Liver bypass significantly increases the transduction efficiency of recombinant adenoviral vectors in the lung, intestine, and kidney

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

Human APC gene expression in rodent colonic epithelium in vivo using liposomal gene delivery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

Adenoviral vectors given intravenously to immunocompromised mice yield stable transduction of the colonic epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

Immunoregulation in the gut: success and failures in human disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

Control of intestinal inflammation by regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

Serum interleukin-18 concentrations in patients with inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

1 reference

7 January 2021

Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-gamma and TNF-alpha production

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

Generation of regulatory gut-homing human T lymphocytes using ex vivo interleukin 10 gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302013

7 January 2021

American Journal of Physiology

6

273

G769

C Fiocchi

1997

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3302013

30 December 2023

Adeno-Associated Viruses

series ordinal

56

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3302013

European Cytokine Network

30 December 2023

72

11

483

CA Dinarello

2000

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3302013

30 December 2023

Identifiers

1 reference

release_3gyutcd43ffbpdr32kwc2wm43i

6 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3gyutcd43ffbpdr32kwc2wm43i

24 November 2022

mapped directly with Wikidata item

1 reference