(Q35122383)

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HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgeni

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6 August 2017

HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgeni (English)

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6 August 2017

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1 June 2020

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Ruchi Srivastava

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1 June 2020

Doran Spencer

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Hawa Vahed

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Patricia P Lopes

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Nhi Thi Uyen Thai

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Christine Wang

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Thanh T Pham

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Jiawei Huang

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Vanessa M Scarfone

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Anthony B Nesburn

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Steven L Wechsler

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Lbachir BenMohamed

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23 January 2015

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Journal of Immunology

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1 June 2020

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1 June 2020

The challenges and opportunities for the development of a T-cell epitope-based herpes simplex vaccine

1 reference

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1 reference

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Effector and central memory T helper 2 cells respond differently to peptide immunotherapy

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Asymptomatic memory CD8+ T cells: from development and regulation to consideration for human vaccines and immunotherapeutics

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28 July 2018

Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes

1 reference

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HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 monochain transgenic/H-2 class I null mice: novel versatile preclinical models of human T cell responses.

1 reference

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HLA-A, B (Class I) and HLA-DR, DQ (Class II) antigens in Turkish patients with recurrent aphthous ulceration and Behçet's disease

1 reference

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Measurement of MHC/peptide interactions by gel filtration or monoclonal antibody capture

1 reference

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28 July 2018

Immunity to ocular and genital herpes simplex viruses infections

1 reference

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28 July 2018

Targeting the genital tract mucosa with a lipopeptide/recombinant adenovirus prime/boost vaccine induces potent and long-lasting CD8+ T cell immunity against herpes: importance of MyD88.

1 reference

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Blocking of PDL-1 interaction enhances primary and secondary CD8 T cell response to herpes simplex virus-1 infection

1 reference

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Future of an "Asymptomatic" T-cell Epitope-Based Therapeutic Herpes Simplex Vaccine

1 reference

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Peptide-MHC class I stability is a better predictor than peptide affinity of CTL immunogenicity

1 reference

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28 July 2018

CD8+ T cells suppress viral replication in the cornea but contribute to VEGF-C-induced lymphatic vessel genesis

1 reference

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28 July 2018

Discovery of potential diagnostic and vaccine antigens in herpes simplex virus 1 and 2 by proteome-wide antibody profiling

1 reference

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28 July 2018

Immunodominant "asymptomatic" herpes simplex virus 1 and 2 protein antigens identified by probing whole-ORFome microarrays with serum antibodies from seropositive asymptomatic versus symptomatic individuals

1 reference

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28 July 2018

Efficacy results of a trial of a herpes simplex vaccine

1 reference

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28 July 2018

Of mice and not humans: how reliable are animal models for evaluation of herpes CD8(+)-T cell-epitopes-based immunotherapeutic vaccine candidates?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340763

28 July 2018

Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340763

28 July 2018

Defining the herpes simplex virus-specific CD8+ T cell repertoire in C57BL/6 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340763

28 July 2018

Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche.

1 reference

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28 July 2018

CD8 T cell cross-reactivity networks mediate heterologous immunity in human EBV and murine vaccinia virus infections

1 reference

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28 July 2018

A novel HLA (HLA-A*0201) transgenic rabbit model for preclinical evaluation of human CD8+ T cell epitope-based vaccines against ocular herpes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340763

28 July 2018

Herpes simplex virus type 2 tegument proteins contain subdominant T-cell epitopes detectable in BALB/c mice after DNA immunization and infection

1 reference

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28 July 2018

Fewer latent herpes simplex virus type 1 and cytotoxic T cells occur in the ophthalmic division than in the maxillary and mandibular divisions of the human trigeminal ganglion and nerve

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340763

28 July 2018

A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340763

28 July 2018

Asymptomatic human CD4+ cytotoxic T-cell epitopes identified from herpes simplex virus glycoprotein B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340763

28 July 2018

Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin.

1 reference

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28 July 2018

Effector CD8 T cell development: a balancing act between memory cell potential and terminal differentiation

1 reference

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28 July 2018

Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340763

28 July 2018

Activation phenotype, rather than central- or effector-memory phenotype, predicts the recall efficacy of memory CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340763

28 July 2018

Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340763

28 July 2018

Topical/mucosal delivery of sub-unit vaccines that stimulate the ocular mucosal immune system

1 reference

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28 July 2018

Identification of protective Lassa virus epitopes that are restricted by HLA-A2.

1 reference

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28 July 2018

Memory of mice and men: CD8+ T-cell cross-reactivity and heterologous immunity

1 reference

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28 July 2018

Diversity of the CD8+ T-cell response to herpes simplex virus type 2 proteins among persons with genital herpes

1 reference

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28 July 2018

Th-cytotoxic T-lymphocyte chimeric epitopes extended by Nepsilon-palmitoyl lysines induce herpes simplex virus type 1-specific effector CD8+ Tc1 responses and protect against ocular infection

1 reference

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28 July 2018

Human immunodeficiency virus mutations during the first month of infection are preferentially found in known cytotoxic T-lymphocyte epitopes

1 reference

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28 July 2018

CD8 memory T cells: cross-reactivity and heterologous immunity.

1 reference

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28 July 2018

Immunodominance among herpes simplex virus-specific CD8 T cells expressing a tissue-specific homing receptor

1 reference

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28 July 2018

Lipopeptide vaccines--yesterday, today, and tomorrow

1 reference

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Intranasal administration of a synthetic lipopeptide without adjuvant induces systemic immune responses

1 reference

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28 July 2018

CD8 CTL from genital herpes simplex lesions: recognition of viral tegument and immediate early proteins and lysis of infected cutaneous cells.

1 reference

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28 July 2018

Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis.

1 reference

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Melanoma antigens recognised by CD8+ and CD4+ T cells.

1 reference

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Induction of CTL response by a minimal epitope vaccine in HLA A*0201/DR1 transgenic mice: dependence on HLA class II restricted T(H) response.

1 reference

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28 July 2018

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1 reference

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The cytotoxic T-cell response to herpes simplex virus type 1 infection of C57BL/6 mice is almost entirely directed against a single immunodominant determinant.

1 reference

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Associations of HLA-A, HLA-B and HLA-C alleles frequency with prevalence of herpes simplex virus infections and diseases across global populations: implication for the development of an universal CD8+ T-cell epitope-based vaccine

1 reference

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Discovering naturally processed antigenic determinants that confer protective T cell immunity

1 reference

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27 September 2018

Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells.

1 reference

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27 September 2018

The role of a glycoprotein K (gK) CD8+ T-cell epitope of herpes simplex virus on virus replication and pathogenicity

1 reference

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27 September 2018

Central memory CD8+ T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression.

1 reference

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The HSV-1 tegument protein pUL46 associates with cellular membranes and viral capsids

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HLA-A*0201-restricted CD8+ cytotoxic T lymphocyte epitopes identified from herpes simplex virus glycoprotein D.

1 reference

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Protective immunity against ocular herpes infection and disease induced by highly immunogenic self-adjuvanting glycoprotein D lipopeptide vaccines

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HLA class I epitopes: recognition of binding sites by mAbs or eluted alloantibody confirmed with single recombinant antigens.

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Identifying HLA supertypes by learning distance functions

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Typing class I HLA-A gene using a nested PCR-RFLP procedure.

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Lipopeptide epitopes extended by an Nepsilon-palmitoyl-lysine moiety increase uptake and maturation of dendritic cells through a Toll-like receptor-2 pathway and trigger a Th1-dependent protective immunity

1 reference

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27 September 2018

Random screening of proteins for HLA-A*0201-binding nine-amino acid peptides is not sufficient for identifying CD8 T cell epitopes recognized in the context of HLA-A*0201.

1 reference

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Human CTLs to wild-type and enhanced epitopes of a novel prostate and breast tumor-associated protein, TARP, lyse human breast cancer cells

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Ex vivo identification, isolation and analysis of tumor-cytolytic T cells.

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Optimizing vaccine design for cellular processing, MHC binding and TCR recognition

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27 September 2018

Systemic immune responses induced by mucosal administration of lipopeptides without adjuvant

1 reference

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27 September 2018

Majority of peptides binding HLA-A*0201 with high affinity crossreact with other A2-supertype molecules

1 reference

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Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3.

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High immunogenicity in chimpanzees of peptides and lipopeptides derived from four new Plasmodium falciparum pre-erythrocytic molecules

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A prospective study of new infections with herpes simplex virus type 1 and type 2. Chiron HSV Vaccine Study Group

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A novel Plasmodium falciparum sporozoite and liver stage antigen (SALSA) defines major B, T helper, and CTL epitopes.

1 reference

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27 September 2018

Identification of wild-type and mutant p53 peptides binding to HLA-A2 assessed by a peptide loading-deficient cell line assay and a novel major histocompatibility complex class I peptide binding assay

1 reference

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27 September 2018

CTL response compensation for the loss of an immunodominant class I-restricted HSV-1 determinant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340763

16 November 2018

Glycoprotein-D–Adjuvant Vaccine to Prevent Genital Herpes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340763

16 November 2018

Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25617474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of an HLA A*0201-restricted CD8(+) T-cell epitope for the glycoprotein B homolog of human herpesvirus 8

1 reference

https://pubmed.ncbi.nlm.nih.gov/25617474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition of variant HIV-1 epitopes from diverse viral subtypes by vaccine-induced CTL

1 reference

https://pubmed.ncbi.nlm.nih.gov/25617474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25617474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1402606

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25617474%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25617474%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25617474%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

ResearchGate publication ID

0 references

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