(Q35122818)

6 August 2017

title

Inactivation of multidrug resistance proteins disrupts both cellular extrusion and intracellular degradation of cAMP (English)

1 reference

6 August 2017

main subject

multiple drug resistance

1 reference

5

Wito Richter

1 reference

6 August 2017

Moses Xie

1

1 reference

6 August 2017

Thomas C Rich

series ordinal

2

1 reference

6 August 2017

Colleen Scheitrum

series ordinal

3

1 reference

6 August 2017

Marco Conti

series ordinal

4

1 reference

6 August 2017

publication date

6 May 2011

1 reference

6 August 2017

published in

Molecular Pharmacology

1 reference

6 August 2017

volume

80

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6 August 2017

issue

2

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6 August 2017

page(s)

281-293

1 reference

PDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblasts

6 August 2017

cites work

1 reference

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9 July 2018

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cAMP efflux from human trophoblast cell lines: a role for multidrug resistance protein (MRP)1 transporter.

9 July 2018

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Compartmentalized cyclic adenosine 3',5'-monophosphate at the plasma membrane clusters PDE3A and cystic fibrosis transmembrane conductance regulator into microdomains

9 July 2018

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Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells.

9 July 2018

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Multidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferation

9 July 2018

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Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules

9 July 2018

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Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4

9 July 2018

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Spatiotemporal coupling of cAMP transporter to CFTR chloride channel function in the gut epithelia

9 July 2018

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Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response.

9 July 2018

1 reference

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Extracellular calcium and cAMP: second messengers as "third messengers"?

9 July 2018

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Pharmacological modulation of cGMP levels by phosphodiesterase 5 inhibitors as a therapeutic strategy for treatment of respiratory pathology in cystic fibrosis

9 July 2018

1 reference

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Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling

9 July 2018

1 reference

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Dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors

9 July 2018

1 reference

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Domain interdependence in the biosynthetic assembly of CFTR.

9 July 2018

1 reference

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PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases

9 July 2018

1 reference

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Macromolecular complexes of cystic fibrosis transmembrane conductance regulator and its interacting partners

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium.

9 July 2018

1 reference

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9 July 2018

Cyclic GMP transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

The extracellular cyclic AMP-adenosine pathway in renal physiology

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Role of MRP4 and MRP5 in biology and chemotherapy

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Extracellular cAMP inhibits proximal reabsorption: are plasma membrane cAMP receptors involved?

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Identification and functional analysis of splice variants of the germ cell soluble adenylyl cyclase

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Analysis and regulation of vasodilator-stimulated phosphoprotein serine 239 phosphorylation in vitro and in intact cells using a phosphospecific monoclonal antibody.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Extrusion of cyclic AMP from pigeon erythrocytes

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Regulation of adenosine 3' :5'-monophosphate efflux from rat glioma cells in culture*

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Probenecide sensitive 3'-5'-cyclic AMP secretion by isoproterenol stimulated glial cells in culture.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Contribution of multidrug resistance protein MRP5 in control of cyclic guanosine 5'-monophosphate intracellular signaling in anterior pituitary cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Dimerization of the type 4 cAMP-specific phosphodiesterases is mediated by the upstream conserved regions (UCRs).

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141887

Atrial natriuretic factor-induced egression of cyclic guanosine 3':5'-monophosphate in cultured vascular smooth muscle and endothelial cells

27 September 2018

1 reference

12 December 2020

cGMP transport by vesicles from human and mouse erythrocytes

1 reference

12 December 2020

Hormonal regulation of a plasma membrane phosphodiesterase in differentiating granulosa cells. Reciprocal actions of follicle-stimulating hormone and a gonadotropin-releasing hormone agonist on cAMP degradation

1 reference

12 December 2020

THE EFFECT OF L-EPINEPHRINE AND OTHER AGENTS ON THE SYNTHESIS AND RELEASE OF ADENOSINE 3',5'-PHOSPHATE BY WHOLE PIGEON ERYTHROCYTES

1 reference

12 December 2020

Identifiers

DOI

10.1124/MOL.111.071134

1 reference

6 August 2017

1 reference

6 August 2017

1 reference