(Q35124859)

6 August 2017

title

N6-Substituted adenosine derivatives: selectivity, efficacy, and species differences at A3 adenosine receptors (English)

1 reference

6 August 2017

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(03)00153-9

3 January 2024

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(03)00153-9

3 January 2024

5

Kenneth A. Jacobson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12754103

3 January 2024

author name string

Zhan-Guo Gao

1

1 reference

6 August 2017

Neli Melman

4

1 reference

6 August 2017

Joshua B. Blaustein

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12754103

3 January 2024

Ariel S. Gross

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12754103

3 January 2024

language of work or name

English

0 references

publication date

1 May 2003

1 reference

6 August 2017

15 May 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12754103

full work available at URL

3 January 2024

https://europepmc.org/articles/pmc3142561?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12754103

https://europepmc.org/articles/PMC3142561

3 January 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12754103

https://europepmc.org/articles/PMC3142561?pdf=render

3 January 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12754103

https://api.elsevier.com/content/article/PII:S0006295203001539?httpAccept=text/xml

3 January 2024

1 reference

DOI

https://api.crossref.org/works/10.1016/S0006-2952(03)00153-9

https://api.elsevier.com/content/article/PII:S0006295203001539?httpAccept=text/plain

3 January 2024

1 reference

DOI

https://api.crossref.org/works/10.1016/S0006-2952(03)00153-9

3 January 2024

published in

Biochemical Pharmacology

1 reference

6 August 2017

volume

65

1 reference

6 August 2017

issue

10

1 reference

6 August 2017

page(s)

1675-1684

1 reference

Synthesis, biological properties, and molecular modeling investigation of the first potent, selective, and water-soluble human A(3) adenosine receptor antagonist

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

Identification by site-directed mutagenesis of residues involved in ligand recognition and activation of the human A3 adenosine receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

5'-O-alkyl ethers of N,2-substituted adenosine derivatives: partial agonists for the adenosine A1 and A3 receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

[(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

N6,5'-Disubstituted adenosine derivatives as partial agonists for the human adenosine A3 receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

The synthesis of new adenosine A3 selective ligands containing bioisosteric isoxazoles

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

Pharmacological characterization of novel A3 adenosine receptor-selective antagonists

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

Molecular cloning and characterization of the human A3 adenosine receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

A binding site model and structure-activity relationships for the rat A3 adenosine receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

Adenosine A3 receptor stimulation and cerebral ischemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

Structure-activity relationships for N6-substituted adenosines at a brain A1-adenosine receptor with a comparison to an A2-adenosine receptor regulating coronary blood flow

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

Agonist activity of 2- and 5'-substituted adenosine analogs and their N6-cycloalkyl derivatives at A1- and A2-adenosine receptors coupled to adenylate cyclase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

2-Chloro-N(6)-cyclopentyladenosine, adenosine A(1) receptor agonist, antagonizes the adenosine A(3) receptor

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

Allosteric modulation of A(3) adenosine receptors by a series of 3-(2-pyridinyl)isoquinoline derivatives

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

A physiological role of the adenosine A3 receptor: sustained cardioprotection

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142561

A modification of a protein-binding method for rapid quantification of cAMP in cell-culture supernatants and body fluid

27 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900153-9

N6-substituted adenosine receptor agonists: potential antihypertensive agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900153-9

7 January 2021

Identifiers

DOI

1 reference

release_x36aayerhvhwtewgggdwkt7wpa

6 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/x36aayerhvhwtewgggdwkt7wpa

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

3142561

1 reference

6 August 2017

1 reference