(Q35125060)

6 August 2017

title

The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells (English)

1 reference

6 August 2017

0 references

1

Véronique Dartois

1 reference

6 August 2017

language of work or name

English

0 references

publication date

3 February 2014

1 reference

Nature Reviews Microbiology

6 August 2017

published in

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6 August 2017

volume

12

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6 August 2017

issue

3

1 reference

6 August 2017

page(s)

159-167

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A medicinal chemists' guide to the unique difficulties of lead optimization for tuberculosis

6 August 2017

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Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions

13 July 2018

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Penetration of anti-infective agents into pulmonary epithelial lining fluid: focus on antifungal, antitubercular and miscellaneous anti-infective agents

13 July 2018

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Pyrazinamide inhibits trans-translation in Mycobacterium tuberculosis

13 July 2018

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Population pharmacokinetics and its role in anti-tuberculosis drug development and optimization of treatment

13 July 2018

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Phosphodiesterase-4 inhibition combined with isoniazid treatment of rabbits with pulmonary tuberculosis reduces macrophage activation and lung pathology

13 July 2018

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13 July 2018

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Rifampicin reduces susceptibility to ofloxacin in rifampicin-resistant Mycobacterium tuberculosis through efflux

13 July 2018

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Spontaneous emergence of multiple drug resistance in tuberculosis before and during therapy

13 July 2018

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Why Do We Use 600 mg of Rifampicin in Tuberculosis Treatment?

13 July 2018

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Location of intra- and extracellular M. tuberculosis populations in lungs of mice and guinea pigs during disease progression and after drug treatment

13 July 2018

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Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism

13 July 2018

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13 July 2018

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Targeting polyamines and inflammation for cancer prevention

13 July 2018

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13 July 2018

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13 July 2018

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Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach

13 July 2018

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Radiosynthesis and bioimaging of the tuberculosis chemotherapeutics isoniazid, rifampicin and pyrazinamide in baboons

13 July 2018

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Clinical pharmacology and lesion penetrating properties of second- and third-line antituberculous agents used in the management of multidrug-resistant (MDR) and extensively-drug resistant (XDR) tuberculosis.

13 July 2018

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Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB.

13 July 2018

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Foamy macrophages and the progression of the human tuberculosis granuloma

13 July 2018

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Computational framework for predictive biodegradation

13 July 2018

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The role of the granuloma in expansion and dissemination of early tuberculous infection

13 July 2018

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PA-824 kills nonreplicating Mycobacterium tuberculosis by intracellular NO release

13 July 2018

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Contrasting effects of human THP-1 cell differentiation on levofloxacin and moxifloxacin intracellular accumulation and activity against Staphylococcus aureus and Listeria monocytogenes

13 July 2018

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Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis

13 July 2018

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Importance of the efflux pump systems in the resistance of Mycobacterium tuberculosis to fluoroquinolones and linezolid.

13 July 2018

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Early bactericidal activity of high-dose rifampin in patients with pulmonary tuberculosis evidenced by positive sputum smears

13 July 2018

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Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910.

13 July 2018

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Limited tissue penetration of taxanes: a mechanism for resistance in solid tumors

13 July 2018

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Proteome-wide profiling of isoniazid targets in Mycobacterium tuberculosis

13 July 2018

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Drug penetration in solid tumours

13 July 2018

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13 July 2018

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13 July 2018

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Emergence of fluoroquinolone resistance in Mycobacterium tuberculosis during continuously dosed moxifloxacin monotherapy in a mouse model

13 July 2018

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Influence of efflux transporters on the accumulation and efflux of four quinolones (ciprofloxacin, levofloxacin, garenoxacin, and moxifloxacin) in J774 macrophages

13 July 2018

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Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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The curious characteristics of pyrazinamide: a review

13 July 2018

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In situ detection of Mycobacterium tuberculosis transcripts in human lung granulomas reveals differential gene expression in necrotic lesions.

13 July 2018

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Effects of AIDS and gender on steady-state plasma and intrapulmonary ethambutol concentrations

13 July 2018

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Pyrazinamide inhibits the eukaryotic-like fatty acid synthetase I (FASI) of Mycobacterium tuberculosis

13 July 2018

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Concentrations of moxifloxacin in serum and pulmonary compartments following a single 400 mg oral dose in patients undergoing fibre-optic bronchoscopy

13 July 2018

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Studies on the treatment of tuberculosis undertaken by the British Medical Research Council tuberculosis units, 1946-1986, with relevant subsequent publications

13 July 2018

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Concentrations of levofloxacin (HR 355) in the respiratory tract following a single oral dose in patients undergoing fibre-optic bronchoscopy

13 July 2018

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13 July 2018

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Purification and Characterization of the Mycobacterium smegmatis Catalase-Peroxidase Involved in Isoniazid Activation

13 July 2018

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The action of antituberculosis drugs in short-course chemotherapy.

13 July 2018

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Does Mycobacterium tuberculosis have plasmids?

13 July 2018

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Polyamine biosynthesis in cells infected with different clinical isolates of human cytomegalovirus

13 July 2018

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Investigation on the serum and lung tissue level of rifampicin in man

13 July 2018

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Efficacy and safety of meropenem-clavulanate added to linezolid-containing regimens in the treatment of MDR-/XDR-TB.

13 July 2018

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Clinical use of the meropenem-clavulanate combination for extensively drug-resistant tuberculosis.

27 September 2018

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Mathematical modeling of pulmonary tuberculosis therapy: Insights from a prototype model with rifampin

27 September 2018

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Nanobead-based interventions for the treatment and prevention of tuberculosis

27 September 2018

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27 September 2018

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The granuloma in tuberculosis--friend or foe?

27 September 2018

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Effect of subinhibitory concentrations of ciprofloxacin on Mycobacterium fortuitum mutation rates

27 September 2018

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Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection

27 September 2018

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A prioritised research agenda for DOTS-Plus for multidrug-resistant tuberculosis (MDR-TB).

27 September 2018

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Rifampicin concentrations in bronchial mucosa, epithelial lining fluid, alveolar macrophages and serum following a single 600 mg oral dose in patients undergoing fibre-optic bronchoscopy.

27 September 2018

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Steady-state propofol brain:plasma and brain:blood partition coefficients and the effect-site equilibration paradox

27 September 2018

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Penetration of sparfloxacin and ciprofloxacin into alveolar macrophages, epithelial lining fluid, and polymorphonuclear leucocytes.

27 September 2018

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Uptake of antibiotics by human alveolar macrophages.

27 September 2018

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Chemotherapy and management of tuberculosis in the United Kingdom: recommendations 1998. Joint Tuberculosis Committee of the British Thoracic Society

27 September 2018

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Clinical and operational value of the extensively drug-resistant tuberculosis definition

16 November 2018

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Institutional control measures for tuberculosis in the era of multiple drug resistance. ACCP/ATS Consensus Conference. American College of Chest Physicians and the American Thoracic Society

16 November 2018

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Chemotherapy and management of tuberculosis in the United Kingdom: recommendations 1998

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO3200

Dynamic persistence of antibiotic-stressed mycobacteria

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO3200

Isoniazid activity is terminated by bacterial persistence

31 March 2020

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Rifomycin levels in the lung and tuberculous lesions in man

31 March 2020

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12 December 2020

Distribution and excretion of radioactive isoniazid in tuberculous patients

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12 December 2020

[Rifampicin and isoniazid concentration in the blood and resected lungs in tuberculosis with combined use of the preparations]

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12 December 2020

Antibiotic uptake by alveolar macrophages

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12 December 2020

[Comparative evaluation of rifampicin and isoniazid penetration into the pathological foci of the lungs in tuberculosis patients]

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12 December 2020

The intracellular activation of pyrazinamide and nicotinamide

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12 December 2020

Identifiers

DOI

10.1038/NRMICRO3200

1 reference

6 August 2017

1 reference

6 August 2017

1 reference