(Q35125652)

6 August 2017

title

Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation (English)

1 reference

6 August 2017

5

1 reference

6 August 2017

M Russo

3

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Claudia Cerella

object named as

C Cerella

2

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author name string

C Spagnuolo

1

1 reference

6 August 2017

S Chateauvieux

4

1 reference

6 August 2017

G L Russo

6

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6 August 2017

language of work or name

English

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publication date

1 July 2011

1 reference

British Journal of Cancer

6 August 2017

published in

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6 August 2017

volume

105

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6 August 2017

issue

2

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6 August 2017

page(s)

221-230

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describes a project that uses

6 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3142809/fullTextXML

inferred from PubMed Central ID database lookup

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28 July 2018

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28 July 2018

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28 July 2018

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Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

28 July 2018

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Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1

28 July 2018

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Dietary flavonoids as proteasome inhibitors and apoptosis inducers in human leukemia cells

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

Chronic lymphocytic leukemia

28 July 2018

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Prostaglandin A2-mediated stabilization of p21 mRNA through an ERK-dependent pathway requiring the RNA-binding protein HuR.

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Calpha

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

Distinct roles for extracellular-signal-regulated protein kinase (ERK) mitogen-activated protein kinases and phosphatidylinositol 3-kinase in the regulation of Mcl-1 synthesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

Antioxidants and cancer, part 3: quercetin

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

Quercetin and anti-CD95(Fas/Apo1) enhance apoptosis in HPB-ALL cell line

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

Elevated Bcl-2/Bax are a consistent feature of apoptosis resistance in B-cell chronic lymphocytic leukaemia and are correlated with in vivo chemoresistance.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

Bcl-2/Bax ratios in chronic lymphocytic leukaemia and their correlation with in vitro apoptosis and clinical resistance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

Bcl-2 expression in chronic lymphocytic leukemia and its correlation with the induction of apoptosis and clinical outcome

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

Clinical staging of chronic lymphocytic leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142809

Non-peptidic small molecule inhibitors against Bcl-2 for cancer therapy.

28 July 2018

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https://api.crossref.org/works/10.1038%2FBJC.2011.229

Chemical inhibitors destabilize HuR binding to the AU-rich element of TNF-alpha mRNA.

21 January 2018

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https://api.crossref.org/works/10.1038%2FBJC.2011.229

Inhibitory effect of flavonoids on 26S proteasome activity

21 January 2018

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https://api.crossref.org/works/10.1038%2FBJC.2011.229

Absorption of quercetin-3-glucoside and quercetin-4'-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.229

Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.229

p38 Mitogen-activated protein kinase stabilizes SMN mRNA through RNA binding protein HuR.

21 January 2018

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https://api.crossref.org/works/10.1038%2FBJC.2011.229

Chemoprevention of cancer by isothiocyanates and anthocyanins: mechanisms of action and structure-activity relationship.

21 January 2018

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https://api.crossref.org/works/10.1038%2FBJC.2011.229

Activation of CD40 in cervical carcinoma cells facilitates CTL responses and augments chemotherapy-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FBJC.2011.229

Activation of phosphatidylinositol 3-kinase is required for tumor necrosis factor-alpha-induced upregulation of matrix metalloproteinase-9: its direct inhibition by quercetin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.229

Mcl-1 is required for Akata6 B-lymphoma cell survival and is converted to a cell death molecule by efficient caspase-mediated cleavage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.229

Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.229

Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.

21 January 2018

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https://api.crossref.org/works/10.1038%2FBJC.2011.229

Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FBJC.2011.229

Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.229

Vinblastine induces acute, cell cycle phase-independent apoptosis in some leukemias and lymphomas and can induce acute apoptosis in others when Mcl-1 is suppressed

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.229

Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.229

Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.229

Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FBJC.2011.229

Chronic lymphocytic leukemia: diagnosis and treatment.

21 January 2018

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https://api.crossref.org/works/10.1038%2FBJC.2011.229

Quercetin enhances CD95- and TRAIL-induced apoptosis in leukemia cell lines

21 January 2018

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12 December 2020

Low MCL-1 mRNA expression correlates with prolonged survival in B-cell chronic lymphocytic leukemia

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12 December 2020

The antiapoptotic effects of blood constituents in patients with chronic lymphocytic leukemia

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12 December 2020

Regulation of antiapoptotic MCL-1 function by gossypol: mechanistic insights from in vitro reconstituted systems

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12 December 2020

Application of the neutral red assay (NR assay) to monolayer cultures of primary hepatocytes: rapid colorimetric viability determination for the unscheduled DNA synthesis test (UDS)

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12 December 2020

In leukaemic CD5+ B cells the expression of BCL-2 gene family is shifted toward protection from apoptosis

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12 December 2020

Increased bcl-2/bax ratio in B-cell chronic lymphocytic leukemia is associated with a progressive pattern of disease

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12 December 2020

Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(-)-gossypol] against diffuse large cell lymphoma

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12 December 2020

Identifiers

DOI

10.1038/BJC.2011.229

1 reference

6 August 2017

1 reference

6 August 2017

1 reference