(Q35128661)

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Improved total synthesis and biological evaluation of potent apratoxin S4 based anticancer agents with differential stability and further enhanced activity

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Improved total synthesis and biological evaluation of potent apratoxin S4 based anticancer agents with differential stability and further enhanced activity (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

4

object named as

Hendrik Luesch

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

Qi-Yin Chen

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Yanxia Liu

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Weijing Cai

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

0 references

publication date

24 March 2014

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Journal of Medicinal Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

57

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

3011-3029

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Apratoxin H and apratoxin A sulfoxide from the Red Sea cyanobacterium Moorea producens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

Asymmetric total synthesis of apratoxin D.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

Systematic Chemical Mutagenesis Identifies a Potent Novel Apratoxin A/E Hybrid with Improved in Vivo Antitumor Activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

Toward more "ideal" polyketide natural product synthesis: a step-economical synthesis of zincophorin methyl ester

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

A more comprehensive and highly practical solution to enantioselective aldehyde crotylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

Targeted therapy in colorectal cancer: current status and future challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

Solid-phase total synthesis of (-)-apratoxin A and its analogues and their biological evaluation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

Evolved diversification of a modular natural product pathway: apratoxins F and G, two cytotoxic cyclic depsipeptides from a Palmyra collection of Lyngbya bouillonii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

EGFR signaling and drug discovery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

Determination of the cyclic depsipeptide FK228 in human and mouse plasma by liquid chromatography with mass-spectrometric detection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

Discovery and structure-activity relationship of antagonists of B-cell lymphoma 2 family proteins with chemopotentiation activity in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

Antitumour efficacy of VEGFR2 tyrosine kinase inhibitor correlates with expression of VEGF and its receptor VEGFR2 in tumour models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

Autocrine stimulation in colorectal carcinoma (CRC): positive autocrine loops in human colorectal carcinoma and applicable significance of blocking the loops

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one (DEPBT): a new coupling reagent with remarkable resistance to racemization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

28 July 2018

Synthesis of α, β-unsaturated γ-amino esters with unprecedented high (E)-stereoselectivity and their conformational analysis in peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

27 September 2018

A biomimetic synthesis of thiazolines using hexaphenyloxodiphosphonium trifluoromethanesulfonate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

27 September 2018

Supported synthesis of oxoapratoxin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

27 September 2018

Apratoxin a reversibly inhibits the secretory pathway by preventing cotranslational translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

27 September 2018

Total synthesis of (-)-apratoxin A, 34-epimer, and its oxazoline analogue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

27 September 2018

Apratoxin E, a cytotoxic peptolide from a guamanian collection of the marine cyanobacterium Lyngbya bouillonii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

27 September 2018

Apratoxin D, a potent cytotoxic cyclodepsipeptide from papua new guinea collections of the marine cyanobacteria Lyngbya majuscula and Lyngbya sordida

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

27 September 2018

A functional genomics approach to the mode of action of apratoxin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

27 September 2018

DEPBT as an efficient coupling reagent for amide bond formation with remarkable resistance to racemization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

27 September 2018

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

27 September 2018

Total structure determination of apratoxin A, a potent novel cytotoxin from the marine cyanobacterium Lyngbya majuscula

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993931

27 September 2018

Strained silacycles in organic synthesis: a new reagent for the enantioselective allylation of aldehydes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24660812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of an oxazoline analogue of apratoxin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/24660812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolution of a protecting-group-free total synthesis: studies en route to the neuroactive marine macrolide (-)-palmyrolide A

1 reference

https://pubmed.ncbi.nlm.nih.gov/24660812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total synthesis of apratoxin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/24660812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Titanium(IV)-mediated tandem deprotection-cyclodehydration of protected cysteine N-amides: biomimetic syntheses of thiazoline- and thiazole-containing heterocycles

1 reference

https://pubmed.ncbi.nlm.nih.gov/24660812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New apratoxins of marine cyanobacterial origin from Guam and Palau

1 reference

https://pubmed.ncbi.nlm.nih.gov/24660812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total synthesis of apratoxin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/24660812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total synthesis of the cyclodepsipeptide apratoxin A and its analogues and assessment of their biological activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/24660812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asymmetric synthesis using diisopropyl tartrate modified (E)- and (Z)-crotylboronates: preparation of the chiral crotylboronates and reactions with achiral aldehydes

1 reference

19 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1021/JA00173A023

Identifiers

10.1021/JM4019965

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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