(Q35129707)

6 August 2017

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title

Death and Baxes: mechanisms of lymphotrophic cytokines (English)

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6 August 2017

Annette R Khaled

1

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6 August 2017

Scott K Durum

series ordinal

2

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6 August 2017

publication date

1 June 2003

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6 August 2017

published in

Immunological Reviews

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6 August 2017

volume

193

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6 August 2017

page(s)

48-57

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Lymphocide: cytokines and the control of lymphoid homeostasis

6 August 2017

cites work

1 reference

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Persistence of memory CD8 T cells in MHC class I-deficient mice

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Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation

21 January 2018

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Homeostatic expansion and phenotypic conversion of naïve T cells in response to self peptide/MHC ligands

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IL-7 is critical for homeostatic proliferation and survival of naive T cells

21 January 2018

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Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells

21 January 2018

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Cytotoxic T-cell memory without antigen

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The long-term maintenance of cytotoxic T cell memory does not require persistence of antigen

21 January 2018

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Homeostasis of alpha beta TCR+ T cells.

21 January 2018

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Reduced expression of Bcl-2 in CD8+ T cells deficient in the IL-15 receptor alpha-chain

21 January 2018

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Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

21 January 2018

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The pleiotropic functions of interleukin 15: not so interleukin 2-like after all.

21 January 2018

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Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

21 January 2018

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Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells

21 January 2018

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Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c))-dependent signaling: comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice

21 January 2018

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Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

21 January 2018

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Constitutive and interleukin-7- and interleukin-15-stimulated DNA binding of STAT and novel factors in cutaneous T cell lymphoma cells.

21 January 2018

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The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

21 January 2018

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Cellular survival: a play in three Akts

21 January 2018

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Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

21 January 2018

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21 January 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

21 January 2018

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Characterization of an interleukin-7-dependent thymic cell line derived from a p53(-/-) mouse

21 January 2018

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bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

21 January 2018

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Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival

21 January 2018

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Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility

21 January 2018

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Overexpression of Bcl-2 does not rescue impaired B lymphopoiesis in IL-7 receptor-deficient mice but can enhance survival of mature B cells.

21 January 2018

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

21 January 2018

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

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PI3K: downstream AKTion blocks apoptosis

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

21 January 2018

1 reference

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

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Bim: a novel member of the Bcl-2 family that promotes apoptosis

21 January 2018

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Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

21 January 2018

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

21 January 2018

1 reference

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Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

21 January 2018

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Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the pro-apoptotic protein Bak.

21 January 2018

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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

21 January 2018

1 reference

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

1 reference

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Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

Jak3 selectively regulates Bax and Bcl-2 expression to promote T-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

Energy metabolism during apoptosis. Bcl-2 promotes survival in hematopoietic cells induced to apoptose by growth factor withdrawal by stabilizing a form of metabolic arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

Apoptosis induced by IL-2 withdrawal is associated with an intracellular acidification

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

Interleukin-3 withdrawal induces an early increase in mitochondrial membrane potential unrelated to the Bcl-2 family. Roles of intracellular pH, ADP transport, and F(0)F(1)-ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

Mouse models for mitochondrial disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Expression and function of the interleukin 7 receptor in murine lymphocytes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Defective T-cell receptor gamma gene rearrangement in interleukin-7 receptor knockout mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

IL-7 receptor and VDJ recombination: trophic versus mechanistic actions

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Defective lymphoid development in mice lacking Jak3

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Interleukin-7 can induce the activation of Jak 1, Jak 3 and STAT 5 proteins in murine T cells.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Bax deficiency partially corrects interleukin-7 receptor alpha deficiency

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Nonionic detergents induce dimerization among members of the Bcl-2 family

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

Activation of a low pH-dependent nuclease by apoptotic agents

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

p90(RSK) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00050.X

7 January 2021

10.1034/J.1600-065X.2003.00050.X

Identifiers

DOI

1 reference

6 August 2017

1 reference