(Q35130860)

English

Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Andrzej Slominski

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

author name string

Tae-Kang Kim

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Zongtao Lin

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

William J Tidwell

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

We Li

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

publication date

27 August 2014

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Molecular and Cellular Endocrinology

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

404

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1-8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Cytochromes p450 and skin cancer: role of local endocrine pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Sensing the environment: regulation of local and global homeostasis by the skin's neuroendocrine system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin membrane receptors in peripheral tissues: distribution and functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin: the smart killer: the human trophoblast as a model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Differential effects of melatonin as a broad range UV-damage preventive dermato-endocrine regulator.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin--a pleiotropic, orchestrating regulator molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin signaling and cell protection function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin: a multitasking molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin decreases cell proliferation and induces melanogenesis in human melanoma SK-MEL-1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

The melatonin-producing system is fully functional in retinal pigment epithelium (ARPE-19).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Inhibitors of melanogenesis increase toxicity of cyclophosphamide and lymphocytes against melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Thirty four years since the discovery of gastrointestinal melatonin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Metabolism of melatonin by cytochrome P450s in rat liver mitochondria and microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Medical implications of melatonin: receptor-mediated and receptor-independent actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin in the skin: synthesis, metabolism and functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin maintains mitochondrial membrane potential and attenuates activation of initiator (casp-9) and effector caspases (casp-3/casp-7) and PARP in UVR-exposed HaCaT keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin and the hair follicle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Localization and biological activities of melatonin in intact and diseased gastrointestinal tract (GIT).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin in edible plants (phytomelatonin): Identification, concentrations, bioavailability and proposed functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Oncostatic effects of the indole melatonin and expression of its cytosolic and nuclear receptors in cultured human melanoma cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Constitutive and UV-induced metabolism of melatonin in keratinocytes and cell-free systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

On the role of melatonin in skin physiology and pathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Functional MT1 and MT2 melatonin receptors in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

The cutaneous serotoninergic/melatoninergic system: securing a place under the sun.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Hair follicle pigmentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melanin pigmentation in mammalian skin and its hormonal regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Isolation of melatonin and 5-methoxyindole-3-acetic acid from bovine pineal glands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Functional activity of serotoninergic and melatoninergic systems expressed in the skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Serotoninergic system in hamster skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Serotoninergic and melatoninergic systems are fully expressed in human skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Conversion of L-tryptophan to serotonin and melatonin in human melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Neuroendocrinology of the skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

In vitro and in vivo formation of two new metabolites of melatonin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin deacetylation: retinal vertebrate class distribution and Xenopus laevis tissue distribution.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin-induced inhibition of melanogenesis in hair follicles in vitro [proceedings]

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin: deacetylation to 5-methoxytryptamine by liver but not brain aryl acylamidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

13 July 2018

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

27 September 2018

Melatonin prevents ultraviolet radiation-induced alterations in plasma membrane potential and intracellular pH in human keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

27 September 2018

Melatonin increases survival of HaCaT keratinocytes by suppressing UV-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

27 September 2018

A role of melatonin in neuroectodermal-mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

27 September 2018

A novel metabolic pathway of melatonin: oxidation by cytochrome C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

27 September 2018

Metabolism of melatonin by human cytochromes p450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

27 September 2018

Hormonal Control of Pigmentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

27 September 2018

Natural melatonin 'knockdown' in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

27 September 2018

Melatonin antagonizes alpha-melanocyte-stimulating hormone enhancement of melanogenesis in mouse melanoma cells by blocking the hormone-induced accumulation of the c locus tyrosinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344443

27 September 2018

Melatonin is metabolized to N-acetyl serotonin and 6-hydroxymelatonin in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/25168391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of serotonin to N-acetylserotonin, melatonin, and 5-methoxytryptamine in hamster skin culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/25168391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melatonin inhibits proliferation and melanogenesis in rodent melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25168391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive regulation of melanin pigmentation by two key substrates of the melanogenic pathway, L-tyrosine and L-dopa

1 reference

https://pubmed.ncbi.nlm.nih.gov/25168391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine skin as a target for melatonin bioregulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25168391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Placental melatonin production and melatonin receptor expression are altered in preeclampsia: new insights into the role of this hormone in pregnancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25168391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melatonin in Peripheral Nerve

1 reference

https://pubmed.ncbi.nlm.nih.gov/25168391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of melatonin on human skin color

1 reference

https://pubmed.ncbi.nlm.nih.gov/25168391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-tyrosinase inhibition of melanogenesis by melatonin in hair follicles in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/25168391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MCE.2014.07.024

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25168391%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q35130860&oldid=1979918119"