(Q54285483)

English

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin.

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scholarly article

1 reference

Europe PubMed Central

27 May 2018

http://europepmc.org/abstract/MED/23110400

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin. (English)

1 reference

Europe PubMed Central

27 May 2018

http://europepmc.org/abstract/MED/23110400

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Detlef Zillikens

5

object named as

Detlef Zillikens

1 reference

Europe PubMed Central

27 May 2018

Konrad Kleszczyński

2

object named as

Konrad Kleszczyński

1 reference

Europe PubMed Central

27 May 2018

http://europepmc.org/abstract/MED/23110400

author name string

Tobias W Fischer

1

1 reference

Europe PubMed Central

27 May 2018

http://europepmc.org/abstract/MED/23110400

Lena H Hardkop

3

1 reference

Europe PubMed Central

27 May 2018

http://europepmc.org/abstract/MED/23110400

Nathalie Kruse

4

1 reference

Europe PubMed Central

27 May 2018

http://europepmc.org/abstract/MED/23110400

publication date

30 October 2012

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Europe PubMed Central

27 May 2018

http://europepmc.org/abstract/MED/23110400

Journal of Pineal Research

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Europe PubMed Central

27 May 2018

http://europepmc.org/abstract/MED/23110400

54

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Europe PubMed Central

27 May 2018

http://europepmc.org/abstract/MED/23110400

3

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Europe PubMed Central

27 May 2018

http://europepmc.org/abstract/MED/23110400

303-312

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Europe PubMed Central

27 May 2018

http://europepmc.org/abstract/MED/23110400

Biological effectiveness of solar UV radiation in humans

1 reference

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Toxic effects of ultraviolet radiation on the skin

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Animals under the sun: effects of ultraviolet radiation on mammalian skin.

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DNA damage, death receptor activation and reactive oxygen species contribute to ultraviolet radiation-induced apoptosis in an essential and independent way.

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Non-linear accumulation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidized DNA damage, during aging

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Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair

1 reference

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21 January 2018

Melatonin as a natural ally against oxidative stress: a physicochemical examination.

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A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases

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High physiological levels of melatonin in the bile of mammals

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High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus.

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Molecular pathways involved in seasonal body weight and reproductive responses governed by melatonin.

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Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling.

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Neuroendocrinology of the skin

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Functional activity of serotoninergic and melatoninergic systems expressed in the skin

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Constitutive and UV-induced metabolism of melatonin in keratinocytes and cell-free systems

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Melatonin maintains mitochondrial membrane potential and attenuates activation of initiator (casp-9) and effector caspases (casp-3/casp-7) and PARP in UVR-exposed HaCaT keratinocytes

1 reference

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Sensing the environment: regulation of local and global homeostasis by the skin's neuroendocrine system

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Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations

1 reference

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Melatonin prevents ultraviolet radiation-induced alterations in plasma membrane potential and intracellular pH in human keratinocytes.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12018

21 January 2018

Melatonin stimulates brain glutathione peroxidase activity.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12018

21 January 2018

Regulation of antioxidant enzymes: a significant role for melatonin

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12018

21 January 2018

Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12018

21 January 2018

Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12018

21 January 2018

Melatonin mitigates mitochondrial malfunction

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12018

21 January 2018

Melatonin preserves the transient mitochondrial permeability transition for protection during mitochondrial Ca(2+) stress in astrocyte

1 reference

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21 January 2018

Dissecting the impact of chemotherapy on the human hair follicle: a pragmatic in vitro assay for studying the pathogenesis and potential management of hair follicle dystrophy

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21 January 2018

Development of a short-term human full-thickness skin organ culture model in vitro under serum-free conditions.

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Towards the development of a simplified long-term organ culture method for human scalp skin and its appendages under serum-free conditions.

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21 January 2018

Enzymic and non-enzymic antioxidants in epidermis and dermis of human skin

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21 January 2018

The similarity of action spectra for thymine dimers in human epidermis and erythema suggests that DNA is the chromophore for erythema.

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21 January 2018

The role of oxidative stress in developmental and reproductive toxicity of tamoxifen

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Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection

1 reference

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21 January 2018

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

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21 January 2018

Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesis

1 reference

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Interaction of singlet molecular oxygen with melatonin and related indoles

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12018

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Superoxide-dependent oxidation of melatonin by myeloperoxidase.

1 reference

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Melatonin-A Highly Potent Endogenous Radical Scavenger and Electron Donor: New Aspects of the Oxidation Chemistry of this Indole Accessed in vitroa

1 reference

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21 January 2018

A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12018

21 January 2018

Effects of ultraviolet B on epidermal morphology, shedding, lipid peroxide, and antioxidant enzymes in Cope's rat snake (Elaphe taeniura).

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https://api.crossref.org/works/10.1111%2FJPI.12018

21 January 2018

Omega-3 fatty acids enhance mitochondrial superoxide dismutase activity in rat organs during post-natal development.

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Protein kinase D mediates mitochondrion-to-nucleus signaling and detoxification from mitochondrial reactive oxygen species

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Inhibition of mitochondria responsible for the anti-apoptotic effects of melatonin during ischemia-reperfusion

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Melatonin induces neural SOD2 expression independent of the NF-kappaB pathway and improves the mitochondrial population and function in old mice

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21 January 2018

Identifiers

10.1111/JPI.12018

1 reference

Europe PubMed Central

27 May 2018

http://europepmc.org/abstract/MED/23110400

1 reference

Europe PubMed Central

27 May 2018

http://europepmc.org/abstract/MED/23110400

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