(Q35131958)

6 August 2017

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title

Proteomics in brain research: potentials and limitations (English)

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6 August 2017

Gert Lubec

1

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author name string

Kurt Krapfenbauer

series ordinal

2

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PubMed ID

12758110

6 August 2017

Michael Fountoulakis

series ordinal

3

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6 August 2017

1 February 2003

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6 August 2017

Progress in Neurobiology

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6 August 2017

69

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6 August 2017

3

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6 August 2017

193-211

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Proteomic profiling of mechanistically distinct enzyme classes using a common chemotype

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Neurofilament proteins NF-L, NF-M and NF-H in brain of patients with Down syndrome and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Proteomic evaluation of intermediary metabolism enzyme proteins in fetal Down's syndrome cerebral cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Analysis of protein sequences and protein complexes by matrix-assisted laser desorption/ionization mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Stability of the human papillomavirus type 18 E2 protein is regulated by a proteasome degradation pathway through its amino-terminal transactivation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Reliable automatic protein identification from matrix-assisted laser desorption/ionization mass spectrometric peptide fingerprints

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Human Umbilical Cord Blood Cells can be Induced to Express Markers for Neurons and Glia.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Oncogenic activation of c-Myb by carboxyl-terminal truncation leads to decreased proteolysis by the ubiquitin-26S proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

High throughput two-dimensional blue-native electrophoresis: a tool for functional proteomics of mitochondria and signaling complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Human and mouse proteomic databases: novel resources in the protein universe.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

New zwitterionic detergents improve the analysis of membrane proteins by two-dimensional electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Translational control of the proteome: relevance to cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Organic solvent extraction as a versatile procedure to identify hydrophobic chloroplast membrane proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Proteomics: current technologies and applications in neurological disorders and toxicology

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Proteomic analysis of the cell envelope fraction of Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Hydrolysis and amino acid composition of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Identification of proteins by matrix-assisted laser desorption ionization-mass spectrometry following in-gel digestion in low-salt, nonvolatile buffer and simplified peptide recovery

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Effect of strong detergents and chaotropes on the detection of proteins in two-dimensional gels

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Enrichment and proteomic analysis of low-abundance bacterial proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Large-scale identification of proteins of Haemophilus influenzae by amino acid composition analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Two-dimensional map of Haemophilus influenzae following protein enrichment by heparin chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Reference map of the low molecular mass proteins of Haemophilus influenzae

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Enrichment and purification of proteins of Haemophilus influenzae by chromatofocusing

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Enrichment of low-copy-number gene products by hydrophobic interaction chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Postmortem changes in the level of brain proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Immunochemical and immunohistochemical study of carbonic anhydrase II in adult rat cerebellum: a marker for oligodendrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Superoxide dismutase SOD1, encoded on chromosome 21, but not SOD2 is overexpressed in brains of patients with Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Aberrant expression of centractin and capping proteins, integral constituents of the dynactin complex, in fetal down syndrome brain

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Proteomic characterization of early-stage differentiation of mouse embryonic stem cells into neural cells induced by all-trans retinoic acid in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

16-BAC/SDS–PAGE: A Two-Dimensional Gel Electrophoresis System Suitable for the Separation of Integral Membrane Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Molecular chaperones in the cytosol: from nascent chain to folded protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Visual stimulation-induced phosphorylation of neurofilament-L in the visual cortex of dark-reared rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Identifying proteins from two-dimensional gels by molecular mass searching of peptide fragments in protein sequence databases

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Advances in protein solubilisation for two-dimensional electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Improved protein solubility in two-dimensional electrophoresis using tributyl phosphine as reducing agent.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Functional proteomics: examining the effects of hypoxia on the cytotrophoblast protein repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

The role of separation science in proteomics research

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Regulation of growth factor induced gene expression by calcium signalling: integrated mRNA and protein expression analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Conventional and functional proteomics using large format two-dimensional gel electrophoresis 24 hours after controlled cortical impact in postnatal day 17 rats

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Enrichment of human brain proteins by heparin chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Genetic analysis of the mouse brain proteome.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Proteomics approach in classifying the biochemical basis of the anticancer activity of the new olomoucine-derived synthetic cyclin-dependent kinase inhibitor, bohemine

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Changes in the levels of low-abundance brain proteins induced by kainic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Changes in the brain protein levels following administration of kainic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

A simple method for displaying the hydropathic character of a protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Mass spectrometry: a tool for the identification of proteins separated by gels

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Effect of protein application mode and acrylamide concentration on the resolution of protein spots separated by two-dimensional gel electrophoresis.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Profiling changes in gene expression during differentiation and maturation of monocyte-derived dendritic cells using both oligonucleotide microarrays and proteomics

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Identification of novel MAP kinase pathway signaling targets by functional proteomics and mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Identification of hepatopoietin dimerization, its interacting regions and alternative splicing of its transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Heat shock protein expression and anti-heat shock protein reactivity in renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

High-throughput profiling of the mitochondrial proteome using affinity fractionation and automation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Mass spectrometry-based methods for phosphorylation site mapping of hyperphosphorylated proteins applied to Net1, a regulator of exit from mitosis in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Manifold reduction of moesin in fetal Down syndrome brain

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Identification of the phosphotyrosine proteome from thrombin activated platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Error-tolerant identification of peptides in sequence databases by peptide sequence tags

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Monitoring daunorubicin-induced alterations in protein expression in pancreas carcinoma cells by two-dimensional gel electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Two-dimensional electrophoresis of membrane proteins using immobilized pH gradients.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

The effects of transcription regulating genes PDR1, pdr1-3 and PDR3 in pleiotropic drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Aberrant expression of signaling-related proteins 14-3-3 gamma and RACK1 in fetal Down syndrome brain (trisomy 21)

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Proteomics and automation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Analysis of membrane proteins by two-dimensional electrophoresis: comparison of the proteins extracted from normal or Plasmodium falciparum-infected erythrocyte ghosts.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

The mitochondrial antioxidant defence system and its response to oxidative stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Proteomics analysis of cellular response to oxidative stress. Evidence for in vivo overoxidation of peroxiredoxins at their active site

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Comparative proteomics as a new tool for exploring human mitochondrial tRNA disorders.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Brain t-complex polypeptide 1 (TCP- 1) related to its natural substrate beta1 tubulin is decreased in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Proteomic investigation of metabolic shift in mammalian cell culture

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Cancer proteomics: from signaling networks to tumor markers.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Alterations of stress related proteins in genetically altered mice revealed by two-dimensional differential in-gel electrophoresis analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Functional proteomics analysis of signal transduction pathways of the platelet-derived growth factor beta receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Proteomics to display lovastatin-induced protein and pathway regulation in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Proteomic analysis of differential protein expression in human nasopharyngeal carcinoma cells induced by NAG7 transfection

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Decreased brain levels of 2',3'-cyclic nucleotide-3'-phosphodiesterase in Down syndrome and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Reduction of actin-related protein complex 2/3 in fetal Down syndrome brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Synaptosomal proteins, beta-soluble N-ethylmaleimide-sensitive factor attachment protein (beta-SNAP), gamma-SNAP and synaptotagmin I in brain of patients with Down syndrome and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Deranged expression of molecular chaperones in brains of patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

Differential expression of molecular chaperones in brain of patients with Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0301-0082%2803%2900036-4

7 January 2021

10.1016/S0301-0082(03)00036-4

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12758110