(Q35136051)

6 August 2017

title

Breast cancer methylomes establish an epigenomic foundation for metastasis (English)

1 reference

6 August 2017

1 reference

Sevin Turcan

2

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Mary Ellen Moynahan

Mary Ellen Moynahan

17

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Larry Norton

Larry Norton

15

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Joan Massagué Solé

Joan Massague

14

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Stephen B. Baylin

11

Stephen B Baylin

1 reference

6 August 2017

16

Linda T Vahdat

1 reference

6 August 2017

3

Andreas Rimner

1 reference

6 August 2017

8

Venkatraman Seshan

1 reference

6 August 2017

Fang Fang

1

1 reference

6 August 2017

Andrew Kaufman

4

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6 August 2017

Dilip Giri

5

1 reference

6 August 2017

Luc G T Morris

6

1 reference

6 August 2017

Ronglai Shen

7

1 reference

6 August 2017

Qianxing Mo

9

1 reference

6 August 2017

Adriana Heguy

10

1 reference

6 August 2017

Nita Ahuja

12

1 reference

6 August 2017

Agnes Viale

13

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6 August 2017

Timothy A Chan

18

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6 August 2017

language of work or name

English

0 references

publication date

1 March 2011

1 reference

Science Translational Medicine

6 August 2017

published in

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6 August 2017

volume

3

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6 August 2017

issue

75

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6 August 2017

page(s)

75ra25

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BRCA1 affects global DNA methylation through regulation of DNMT1

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake.

13 July 2018

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Epigenetic inactivation of the potential tumor suppressor gene FOXF1 in breast cancer

13 July 2018

1 reference

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Basal-like breast cancer displays distinct patterns of promoter methylation

13 July 2018

1 reference

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Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

13 July 2018

1 reference

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Genome remodelling in a basal-like breast cancer metastasis and xenograft

13 July 2018

1 reference

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Quantitative methylation profiling in tumor and matched morphologically normal tissues from breast cancer patients

13 July 2018

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LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer

13 July 2018

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Smad signaling is required to maintain epigenetic silencing during breast cancer progression.

13 July 2018

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DNA hypermethylation of ESR1 and PGR in breast cancer: pathologic and epidemiologic associations

13 July 2018

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DNA methylation as a biomarker in breast cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

PIK3CA mutation associates with improved outcome in breast cancer.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

13 July 2018

1 reference

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Agglomerative epigenetic aberrations are a common event in human breast cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

DNA methylation markers and early recurrence in stage I lung cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

13 July 2018

Cancer statistics, 2008

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

DNA hypermethylation of PITX2 is a marker of poor prognosis in untreated lymph node-negative hormone receptor-positive breast cancer patients

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

The genomic landscapes of human breast and colorectal cancers

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

High-throughput methylation profiling by MCA coupled to CpG island microarray

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Molecular concepts analysis links tumors, pathways, mechanisms, and drugs

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Genetic determinants of cancer metastasis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Lung metastasis genes couple breast tumor size and metastatic spread.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

The epigenomics of cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

The consensus coding sequences of human breast and colorectal cancers

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

DNA methylation profiles of female steroid hormone-driven human malignancies.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Epigenetic silencing and deletion of the BRCA1 gene in sporadic breast cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study

13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Control of developmental regulators by Polycomb in human embryonic stem cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Genes that mediate breast cancer metastasis to lung

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Adjuvant chemotherapy in older and younger women with lymph node-positive breast cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Gene silencing in cancer in association with promoter hypermethylation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Statistical significance for genomewide studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Repeated observation of breast tumor subtypes in independent gene expression data sets

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

DAVID: Database for Annotation, Visualization, and Integrated Discovery

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Worms gang up on bacteria

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Gene expression profiling predicts clinical outcome of breast cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Molecular portraits of human breast tumours

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

CpG island methylator phenotype in colorectal cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Expression of Wnt genes and frizzled 1 and 2 receptors in normal breast epithelium and infiltrating breast carcinoma.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146366

Molecular Portraits and 70-Gene Prognosis Signature Are Preserved throughout the Metastatic Process of Breast Cancer

27 September 2018

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12 December 2020

Gene-expression profiles in hereditary breast cancer

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12 December 2020

Prevalence of aberrant methylation of p14ARF over p16INK4a in some human primary tumors

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12 December 2020

Hypermethylation in histologically distinct classes of breast cancer

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12 December 2020

Colon cancer: it's CIN or CIMP

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12 December 2020

The fundamental role of epigenetic events in cancer

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12 December 2020

10.1126/SCITRANSLMED.3001875

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference