(Q35138123)

6 August 2017

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title

Inhibitors of glycosyl-phosphatidylinositol anchor biosynthesis (English)

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Cristiana Santos de Macedo

6 August 2017

object named as

Cristiana Santos de Macedo

1

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author name string

Hosam Shams-Eldin

2

1 reference

6 August 2017

Terry K Smith

3

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6 August 2017

Ralph T Schwarz

4

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6 August 2017

Nahid Azzouz

5

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6 August 2017

1 March 2003

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6 August 2017

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6 August 2017

85

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6 August 2017

3-4

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6 August 2017

465-472

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Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Recent developments in the cell biology and biochemistry of glycosylphosphatidylinositol lipids (review).

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

The GPI biosynthetic pathway as a therapeutic target for African sleeping sickness.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Mammalian GPI proteins: sorting, membrane residence and functions

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

High lateral mobility of endogenous and transfected alkaline phosphatase: a phosphatidylinositol-anchored membrane protein

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Structure-activity relationship of synthetic phosphoinositolglycans mimicking metabolic insulin action

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Architecture of the yeast cell wall. Beta(1-->6)-glucan interconnects mannoprotein, beta(1-->)3-glucan, and chitin

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Glycosylphosphatidylinositol anchors of membrane glycoproteins are binding determinants for the channel-forming toxin aerolysin.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Clostridium septicum alpha toxin uses glycosylphosphatidylinositol-anchored protein receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Antigenic variation in trypanosomes: secrets surface slowly

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

An active carbonyl formed during glycosylphosphatidylinositol addition to a protein is evidence of catalysis by a transamidase

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

A cell-free assay for glycosylphosphatidylinositol anchoring in African trypanosomes. Demonstration of a transamidation reaction mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Glycosylphosphatidylinositol biosynthesis validated as a drug target for African sleeping sickness

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Temperature-sensitive yeast GPI anchoring mutants gpi2 and gpi3 are defective in the synthesis of N-acetylglucosaminyl phosphatidylinositol. Cloning of the GPI2 gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

PIG-C, one of the three human genes involved in the first step of glycosylphosphatidylinositol biosynthesis is a homologue of Saccharomyces cerevisiae GPI2

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

The GPI1 homologue from Plasmodium falciparum complements a Saccharomyces cerevisiae GPI1 anchoring mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Inhibition of the GlcNAc transferase of the glycosylphosphatidylinositol anchor biosynthesis in African trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Early steps in glycosylphosphatidylinositol biosynthesis in Leishmania major.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Substrate specificity of the N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol membrane anchor biosynthesis in African trypanosomes and human cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Substrate specificity of the Plasmodium falciparum glycosylphosphatidylinositol biosynthetic pathway and inhibition by species-specific suicide substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Differences between the trypanosomal and human GlcNAc-PI de-N-acetylases of glycosylphosphatidylinositol membrane anchor biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Parasite and mammalian GPI biosynthetic pathways can be distinguished using synthetic substrate analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Selective inhibitors of the glycosylphosphatidylinositol biosynthetic pathway of Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Specificity of GlcNAc-PI de-N-acetylase of GPI biosynthesis and synthesis of parasite-specific suicide substrate inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Specificities of enzymes of glycosylphosphatidylinositol biosynthesis in Trypanosoma brucei and HeLa cells

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Biosynthesis of glycosylphosphatidylinositols of Plasmodium falciparum in a cell-free incubation system: inositol acylation is needed for mannosylation of glycosylphosphatidylinositols

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Mammalian glycophosphatidylinositol anchor transfer to proteins and posttransfer deacylation

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

The role of inositol acylation and inositol deacylation in GPI biosynthesis in Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Phenylmethanesulphonyl fluoride inhibits GPI anchor biosynthesis in the African trypanosome

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Anchoring and degradation of glycolipid-anchored membrane proteins by L929 versus by LM-TK- mouse fibroblasts: implications for anchor biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositol

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Its8, a fission yeast homolog of Mcd4 and Pig-n, is involved in GPI anchor synthesis and shares an essential function with calcineurin in cytokinesis

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Saccharomyces cerevisiae GPI10, the functional homologue of human PIG-B, is required for glycosylphosphatidylinositol-anchor synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

The essential Smp3 protein is required for addition of the side-branching fourth mannose during assembly of yeast glycosylphosphatidylinositols

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Biosynthesis of glycosyl-phosphatidylinositol lipids in Trypanosoma brucei: involvement of mannosyl-phosphoryldolichol as the mannose donor

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Possible localisation of dolichol-dependent mannosyltransferase of Trypanosoma brucei to the rough endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Evidence for N-linked glycosylation in Toxoplasma gondii

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Apparent lack of N-glycosylation in the asexual intraerythrocytic stage of Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

N-linked glycoproteins are related to schizogony of the intraerythrocytic stage in Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

The mannosylation of dolichol-diphosphate oligosaccharides in relation to the formation of oligosaccharides and glycoproteins in pig-liver endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Early lipid intermediates in glycosyl-phosphatidylinositol anchor assembly are synthesized in the ER and located in the cytoplasmic leaflet of the ER membrane bilayer.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Photolabeling of Prostaglandin Endoperoxide H Synthase-1 with 3-Trifluoro-3-(m-Iiodophenyl)diazirine as a Probe of Membrane Association and the Cyclooxygenase Active Site

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Parasite-Specific Inhibition of the Glycosylphosphatidylinositol Biosynthetic Pathway by Stereoisomeric Substrate Analogues†

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Hydrophobic mannosides act as acceptors for trypanosome α-mannosyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Fluoroglucose-inhibition of protein glycosylation in vivo. Inhibition of mannose and glucose incorporation into lipid-linked oligosaccharides

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Glycosylation of influenza virus proteins in the presence of fluoroglucose occurs via a different pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Specificity of GDP-Man:dolichyl-phosphate mannosyltransferase for the guanosine diphosphate esters of mannose analogues containing deoxy and deoxyfluoro substituents

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Dissecting glycoprotein biosynthesis by the use of specific inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

2-Deoxyglucose: inhibition of parasitemia and of glucosamine incorporation into glycosylated macromolecules, in malarial parasites (Plasmodium falciparum)

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Transient N-acetylgalactosaminylation of mannosyl phosphate side chain in Paramecium primaurelia glycosylphosphatidylinositols

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Nature of glycosylphosphatidylinositols produced by mouse embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

The effect of mannosamine on the formation of lipid-linked oligosaccharides and glycoproteins in canine kidney cells

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Cytodifferentiation in Tetrahymena vorax is linked to glycosyl-phosphatidylinositol-anchored protein assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Developmental stage-specific biosynthesis of glycosylphosphatidylinositol anchors in intraerythrocytic Plasmodium falciparum and its inhibition in a novel manner by mannosamine.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Glucosamine inhibits inositol acylation of the glycosylphosphatidylinositol anchors in intraerythrocytic Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

GPI anchor biosynthesis in yeast: phosphoethanolamine is attached to the alpha1,4-linked mannose of the complete precursor glycophospholipid

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Identification of a species-specific inhibitor of glycosylphosphatidylinositol synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

1,10-Phenanthroline inhibits glycosylphosphatidylinositol anchoring by preventing phosphoethanolamine addition to glycosylphosphatidylinositol anchor precursors

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Differential effect of 1,10-phenanthroline on mammalian, yeast, and parasite glycosylphosphatidylinositol anchor synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Fatty acid remodeling: A novel reaction sequence in the biosynthesis of trypanosome glycosyl phosphatidylinositol membrane anchors

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Delineation of three pathways of glycosylphosphatidylinositol biosynthesis in Leishmania mexicana. Precursors from different pathways are assembled on distinct pools of phosphatidylinositol and undergo fatty acid remodeling

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Addition of lipid substituents of mammalian protein glycosylphosphoinositol anchors

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Alternative lipid remodelling pathways for glycosylphosphatidylinositol membrane anchors in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Lipid remodeling leads to the introduction and exchange of defined ceramides on GPI proteins in the ER and Golgi of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Specialized fatty acid synthesis in African trypanosomes: myristate for GPI anchors

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

An analog of myristic acid with selective toxicity for African trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Toxicity of myristic acid analogs toward African trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

How glycosylphosphatidylinositol-anchored membrane proteins are made

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Biosynthesis of glycosylphosphatidylinositol (GPI)-anchored membrane proteins in intact cells: specific amino acid requirements adjacent to the site of cleavage and GPI attachment

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Comparative efficiencies of C-terminal signals of native glycophosphatidylinositol (GPI)-anchored proproteins in conferring GPI-anchoring

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

Requirements for glycosylphosphatidylinositol attachment are similar but not identical in mammalian cells and parasitic protozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2803%2900065-8

7 January 2021

10.1016/S0300-9084(03)00065-8

Identifiers

DOI

1 reference

6 August 2017

1 reference