(Q35138481)

6 August 2017

title

p53 downregulates Down syndrome-associated DYRK1A through miR-1246. (English)

1 reference

6 August 2017

Yu Zhang

1

1 reference

6 August 2017

Jun-Ming Liao

series ordinal

2

1 reference

6 August 2017

Shelya X Zeng

series ordinal

3

1 reference

6 August 2017

Hua Lu

series ordinal

4

1 reference

6 August 2017

publication date

3 June 2011

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6 August 2017

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6 August 2017

volume

12

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6 August 2017

issue

8

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6 August 2017

page(s)

811-817

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TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

The origins and evolution of the p53 family of genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

Opposing roles for calcineurin and ATF3 in squamous skin cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

p53 represses c-Myc through induction of the tumor suppressor miR-145

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

MicroRNAs: target recognition and regulatory functions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase Itch for degradation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

A microRNA component of the p53 tumour suppressor network

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

SSRP1 functions as a co-activator of the transcriptional activator p63

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

p63 is a p53 homologue required for limb and epidermal morphogenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region"

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

An enhanced immune response in mice lacking the transcription factor NFAT1.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

WAF1, a potential mediator of p53 tumor suppression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

Identification of a putative regulator of early T cell activation genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling.

13 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2011.98

Alzheimer's disease in the parents of women with trisomic spontaneous abortions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2011.98

The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2011.98

Targeted deletion of the calcineurin inhibitor DSCR1 suppresses tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2011.98

The p53 family in differentiation and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2011.98

Pharmacotherapy for cognitive impairment in a mouse model of Down syndrome.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147276

Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA

27 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2011.98

21 January 2018

Identifiers

DOI

10.1038/EMBOR.2011.98

1 reference

6 August 2017

1 reference

6 August 2017

1 reference