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From genes to aging in Drosophila
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12779251
retrieved
6 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
From genes to aging in Drosophila
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12779251
retrieved
6 August 2017
main subject
Drosophila
0 references
author
Stephen L. Helfand
series ordinal
1
object named as
Stephen L Helfand
1 reference
stated in
Europe PubMed Central
PubMed ID
12779251
retrieved
6 August 2017
author name string
Blanka Rogina
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12779251
retrieved
6 August 2017
publication date
1 January 2003
1 reference
stated in
Europe PubMed Central
PubMed ID
12779251
retrieved
6 August 2017
published in
Advances in Genetics
1 reference
stated in
Europe PubMed Central
PubMed ID
12779251
retrieved
6 August 2017
volume
49
1 reference
stated in
Europe PubMed Central
PubMed ID
12779251
retrieved
6 August 2017
page(s)
67-109
1 reference
stated in
Europe PubMed Central
PubMed ID
12779251
retrieved
6 August 2017
cites work
Review of genetic investigations into the aging processes of Drosophila
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic alteration of normal aging processes is responsible for extended longevity in Drosophila.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
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Metabolic rates in genetically based long lived strains of Drosophila
1 reference
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Crossref
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7 January 2021
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Genetic and environmental factors regulating the expression of an extended longevity phenotype in a long lived strain of Drosophila
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
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Factors contributing to the plasticity of the extended longevity phenotypes of Drosophila
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
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inferred from DOI database lookup
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
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inferred from DOI database lookup
Extending the lifespan of long-lived mice
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
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Doxycycline-induced transgene expression during Drosophila development and aging
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
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Failure to confirm increased longevity in Drosophila melanogaster submitted to a food restriction procedure.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA synthesis in the absence of somatic cell division associated with ageing in Drosophila subobscura
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Slowing of mortality rates at older ages in large medfly cohorts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
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Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Female fitness in Drosophila melanogaster: an interaction between the effect of nutrition and of encounter rate with males.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
No reduction in the cost of mating for Drosophila melanogaster females mating with spermless males.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cost of mating in Drosophila melanogaster females is mediated by male accessory gland products
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
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Extension of the Drosophila lifespan by overexpression of a protein repair methyltransferase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phenotypic plasticity and selection in Drosophila life-history evolution. I. Nutrition and the cost of reproduction
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Independence of Temperature of the Rate of Ageing in Drosophila subobscura
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Demography of genotypes: failure of the limited life-span paradigm in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lifespan, QTLs, age-specificity, and pleiotropy in Drosophila
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metabolic reserves and evolved stress resistance in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A coordinate upregulation of antioxidant gene activities is associated with the delayed onset of senescence in a long-lived strain of Drosophila.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two-dimensional protein electrophoretic analysis of postponed aging in Drosophila.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
On the Nature of the Function Expressive of the Law of Human Mortality, and on a New Mode of Determining the Value of Life Contingencies
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Age-specific mortality and reproduction respond to adult dietary restriction in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic pathways that regulate ageing in model organisms
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Crossroads of aging in the nematode Caenorhabditis elegans.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
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Rejuvenating views of the ageing process
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
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Signals from the reproductive system regulate the lifespan of C. elegans
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Proliferation pattern of postembryonic neuroblasts in the brain of Drosophila melanogaster
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Metabolic control and ageing
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hypothesis: Interventions That Increase the Response to Stress Offer the Potential for Effective Life Prolongation and Increased Health
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
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The art and design of genetic screens: Drosophila melanogaster
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Life extension in Drosophila by feeding a drug.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic suppression of polyglutamine toxicity in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A C. elegans mutant that lives twice as long as wild type
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Heat-induced longevity extension in Drosophila. I. Heat treatment, mortality, and thermotolerance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Aging-specific expression of Drosophila hsp22.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased hsp22 RNA levels in Drosophila lines genetically selected for increased longevity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extended life-span and stress resistance in the Drosophila mutant methuselah
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is There a Temperature Coefficient for the Duration of Life?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selection for longevity confers resistance to low-temperature stress in Drosophila melanogaster.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selection for life span in Drosophila melanogaster
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Successful selection for increased longevity in Drosophila: analysis of the survival data and presentation of a hypothesis on the genetic regulation of longevity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SELECTION FOR DELAYED SENESCENCE IN DROSOPHILA MELANOGASTER.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caloric restriction and aging: an update
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Locomotor activity as a function of age and life span in Drosophila melanogaster overexpressing hsp70
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of temperature on the life span, vitality and fine structure of Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative action of antioxidant defense systems in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of Mn-containing superoxide dismutase in transgenic Drosophila melanogaster
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Antioxidant status and stress resistance in long- and short-lived lines of Drosophila melanogaster
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Postponed aging and desiccation resistance in Drosophila melanogaster
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Detection in situ of genomic regulatory elements in Drosophila
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effects of catalase gene overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of Cu-Zn superoxide dismutase overexpression of life span and resistance to oxidative stress in transgenic Drosophila melanogaster.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relationship between catalase activity, life span and some parameters associated with antioxidant defenses in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A conditional tissue-specific transgene expression system using inducible GAL4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sexual activity reduces lifespan of male fruitflies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methuselah among nematodes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted neuronal gene expression and longevity in Drosophila.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila drop-dead mutations accelerate the time course of age-related markers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extended life-span conferred by cotransporter gene mutations in Drosophila.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P[Switch], a system for spatial and temporal control of gene expression in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A modular misexpression screen in Drosophila detecting tissue-specific phenotypes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Laboratory Evolution of Postponed Senescence in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A test of evolutionary theories of senescence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selection on stress resistance increases longevity in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relationship between physical activity and life span in the adult housefly, Musca domestica
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative stress, caloric restriction, and aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Simultaneous overexpression of copper- and zinc-containing superoxide dismutase and catalase retards age-related oxidative damage and increases metabolic potential in Drosophila melanogaster.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Slow aging during insect reproductive diapause: why butterflies, grasshoppers and flies are like worms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chaperoning extended life.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A relation between longevity, metabolic rate, and activity in shaker mutants of Drosophila melanogaster.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mosaic mapping of foci associated with longevity in the neurological mutants Hk1 and Sh5 of Drosophila melanogaster.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biodemographic trajectories of longevity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Muscle-specific expression of Drosophila hsp70 in response to aging and oxidative stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of gene expression during aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2660%2803%2901002-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0065-2660(03)01002-2
1 reference
stated in
Europe PubMed Central
PubMed ID
12779251
retrieved
6 August 2017
PubMed ID
12779251
1 reference
stated in
Europe PubMed Central
PubMed ID
12779251
retrieved
6 August 2017
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